Results 81 to 90 of about 88,069 (311)

Bamboo Fiber Extraction Method Using a Machining Center

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2008
Recently, materials made of natural resources have been gaining attention. In particular, high expectations are placed on bamboo fiber. However, conventional bamboo fiber extraction techniques have problems, primarily involving quality, accuracy, and ...
Keiji OGAWA   +3 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Toolpaths Programming in an Intelligent Step-NC Manufacturing Context [PDF]

open access: yes, 2008
The current language for CNC programming is G-code which dates from the beginning of the eighties with the norm ISO 6983. With the new technologies, G-code becomes obsolete.
Hascoët, Jean-Yves   +2 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Elucidation of the polishing mechanism by the magnetic polishing brush

open access: yesNihon Kikai Gakkai ronbunshu, 2016
Nowadays, a free-form surface, such as molding die surface, is required to be finished by reducing the environmental burden. Therefore, a novel polishing technology is needed with a less abrasive slurry,for the reduction of which a magnetic abrasive ...
Lei MA   +4 more
doaj   +1 more source

Toward Practices for Human-Centered Machine Learning

open access: yesCommunications of the ACM, 2023
Designing for the social, cultural, and ethical implications of ML are just as important as its technical advances.
openaire   +2 more sources

Assessing carbon dioxide emission reduction potentials of improved manufacturing processes using multiregional input output frameworks [PDF]

open access: yes, 2016
Evaluating innovative process technologies has become highly important within the last decades. As standard tools different Life Cycle Assessment methods have been established, which are continuously improved.
Burger, Mia   +10 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Process simulation for 5-axis machining using generalized milling tool geometries [PDF]

open access: yes, 2010
Multi-axis machining (especially 5-axis machining) is widely used in precision machining for automotive, aerospace and die-mold manufacturing. The goal in precision machining is to increase production while meeting high part quality needs which can be ...
Budak, Erhan   +2 more
core  

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