Results 71 to 80 of about 88,069 (311)

Scheduling of a machining center

Mathematical and Computer Modelling, 1996
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Wang, J., Luh, P. B.
openaire   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Research of Spiral Bevel Gear Tooth Surface Modification Technique based on Machining Center

Jixie chuandong, 2016
On the consideration of the existing tooth surface modification technology of spiral bevel gear limited to special milling tooth machine,a kind of tooth surface modification method based on the machining center is put forward.
Wang Lei, Cao Xuemei, Deng Xiaozhong, Lei Baozhen   +3 more
doaj  

Fabrication of magic-mirror with magnetic polishing and end-milling on machining center

Nihon Kikai Gakkai ronbunshu, 2014
Recently, with the fabrication of the magic-mirror having the micro C2-continuous surface, it is difficult to hand down magic-mirror fabrication technology, due to downsizing of veteran engineers or even their successors.
Tatsuya FURUKI, Lei MA, Toshiki HIROGAKI, Eiichi AOYAMA, Keiji OGAWA   +4 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tool Path Generation for the Formation of a Geometric Surface Pattern on a Curved Surface by Patch Division Milling

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2008
A textural surface pattern is used to add a physical or decorative function to an object's surface. We have proposed a milling technique involving patch division that can quickly generate a geometric surface pattern using a common profile-forming ...
Hiroshi MATSUDA, Hiroyuki SASAHARA, Masaaki FUKUDA, Masaomi TSUTSUMI   +3 more
doaj   +1 more source

Using Ensembles for Accurate Modelling of Manufacturing Processes in an IoT Data-Acquisition Solution

Applied Sciences, 2020
The development of complex real-time platforms for the Internet of Things (IoT) opens up a promising future for the diagnosis and the optimization of machining processes.
José Luis Garrido-Labrador, Daniel Puente-Gabarri, José Miguel Ramírez-Sanz, David Ayala-Dulanto, Jesus Maudes   +4 more
doaj   +1 more source

High-speed Fabrication of Micro-channels using Line-based Laser Induced Plasma Micromachining (L-LIPMM) [PDF]

, 2013
Micro-texturing of surfaces has various applications that often involve texturing over large (macro-scale) areas with high precision and resolution. This demands scalability and speed of texturing while retaining feature sizes on the order of a few ?m.
Cao, Jian, Ehmann, Kornel, Malhotra, Rajiv, Saxena, Ishan   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Motion error estimation of circular arc interpolation cutter path of machining center produced by NC linear acceleration/deceleration processing

Nihon Kikai Gakkai ronbunshu
From the machining center (MC) user’s point of view, this paper, as the second report of a systematic study, proposes a practical approach to estimate the trajectory error of a circular arc interpolation cutter path produced by the NC linear acceleration/
Hua QIU, Tetsurou YAMAGUCHI
doaj   +1 more source