Results 41 to 50 of about 13,240 (266)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Study on Kinematic Structure Performance and Machining Characteristics of 3-Axis Machining Center

open access: yesApplied Sciences, 2023
The rigidity and natural frequency of machine tools considerably influence cutting and generate great forces when the tool is in contact with the workpiece.
Tzu-Chi Chan   +3 more
doaj   +1 more source

Vibrations in the Machining System of the Vertical Machining Center

open access: yesProcedia Engineering, 2012
AbstractThe paper discusses the equipment and method for measuring vibrations in the tool-workpiece system during face milling. The experimental results show that the vibrations in the tool-workpiece system are dependent on the feed rate. The relationships between vibrations and time, as well as the standard deviation of the displacements and feed are ...
Miko, Edward, Nowakowski, Łukasz
openaire   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

TRANSIENT RESPONSE ANALYSIS OF MACHINING CENTER UNDER IMPACT OF HIGH ACCELERATION

open access: yesJixie qiangdu, 2018
The manufacturing processing of blade,which has complicated structure and irregular surface shape,become increasingly high-speed.Thus,high acceleration is required to ensure the rapid movement of each axis.At the same time,the machining accuracy should ...
MI Jie, ZHEN Zhen, ZHU YingPing
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Research of Spiral Bevel Gear Tooth Surface Modification Technique based on Machining Center

open access: yesJixie chuandong, 2016
On the consideration of the existing tooth surface modification technology of spiral bevel gear limited to special milling tooth machine,a kind of tooth surface modification method based on the machining center is put forward.
Wang Lei   +3 more
doaj  

High precision manufacturing method of multi-thread worm wheel using 5-axis machining center

open access: yesNihon Kikai Gakkai ronbunshu, 2019
In recent years, the speeding up of a rotary table using a worm gear pair has been required. In order to perform the speeding up of a rotary table, the multi-thread worm wheel is adopted in some cases. When a hob tool for cutting a worm wheel is likewise
Shigenori HAMADA   +2 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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