Results 141 to 150 of about 2,322 (298)
Mechanical properties and machining of aluminum-silicon alloys modified by bismuth or tin [PDF]
, 2013 The dry machining performance, microstructure and mechanical properties of hypoeutectic and hypereutectic Al-Si alloys modified with different amounts of Bi and Sn, and cast at different cooling rates, were studied. The measured cutting and thrust forces
Chen, Peisheng
core
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
FEBS Open Bio, EarlyView.Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
Stress and Strain Distributions during Machining of Ti-6Al-4V at Ambient and Cryogenic Temperatures [PDF]
, 2014 Dry and liquid nitrogen pre-cooled Ti-6Al-4V samples were machined at a cutting speed of 43.2 m/min and at low (0.1 mm/rev) to high (0.4 mm/rev) feed rates for understanding the effects of temperature and strain rate on chip microstructures.
Rahman, Md. Fahim
core
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Design of Subsea Vertical Tree for 500 m Depth Water
Shiyou jixie, 2018 Subsea tree is the key equipment for deepwater oil and gas development. To sort out and extract the latest research progress and achievements of the subsea tree and to guide the design and development of related domestic products, the technical status of
Sun Chuanxuan +5 more
doaj
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Workpiece localization : theory, algorithms and implementation [PDF]
, 1999 Workpiece localization refers to the following problem: assuming a rigid workpiece is arbitrarily fixtured to a work table, determine the position and orientation of the workpiece frame relative to some known world reference frame.
Chu, Yunxian
core
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source