Results 71 to 80 of about 43,039 (317)

Residual Stresses in Machining of AISI 52100 Steel under Dry and Cryogenic Conditions: A Brief Summary [PDF]

, 2014
17th Conference on Material Forming (ESAFORM) - FinlandResidual stress is one of the most important surface integrity parameter that can significantly affect the service performance of a mechanical component, such as: contact fatigue, corrosion ...
OUTEIRO, José, BATISTA, A.C., BATISTA, Antonio, UMBRELLO, Domenico, CARUSO, SERAFINO, MARTINS DO OUTEIRO, Jose Carlos   +5 more
core  

Evalaution and optimization of laser cutting parameters for plywood materials [PDF]

, 2013
Laser process parameters influence greatly the width of kerfs and quality of the cut edges. This article reports experiments on the laser plywood-cutting performance of a CW 1.5 kW CO2¬ Rofin laser, based on design of experiments (DOE).
Alrashed, K., Olabi, Abdul-Ghani, Rossini, Nicola, Eltawahni, Hayat, Dassisti, Michele, Aldaham, T., Benyounis, Khaled   +6 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

A review of wood machining literature with a special focus on sawing [PDF]

, 2013
In this review, fundamental wood machining research is evaluated to determine the general cutting mechanics of simple, orthogonal, and oblique cutting tools. Simple tool force trends and chip formation characteristics are indentified here, along with the
Phil Hackney, Naylor, Andrew, Hackney, P, Hackney, Philip, Andrew Naylor, Naylor, A   +5 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Process Mechanics and Surface Integrity Induced by Dry and Cryogenic Machining of AZ31B-O Magnesium Alloy [PDF]

, 2013
The corrosion resistance of magnesium alloys depends mainly on its surface integrity. Previous experimental studies have shown that machining can induces small (nano-scale) grain size, compressive residual stresses and basal plane crystallographic ...
Fromentin, G., GERMAIN, Guénaël, Germain, G., Batista, A.C., POULACHON, Gerard, G. Germain, BATISTA, Antonio, G. Poulachon, ROSSI, FREDERIC, Outeiro, J.C., OUTEIRO, José, G. Fromentin, FROMENTIN, Guillaume, A.C. Batista, F. Rossi, Poulachon, G., Rossi, F., MARTINS DO OUTEIRO, Jose Carlos, J.C. Outeiro   +18 more
core   +1 more source

Optimasi Parameter Permesinan Terhadap Tingkat Kekasaran Permukaan Aluminium Proses Pembubutan Dengan Metode Taguchi

Metal: Jurnal Sistem Mekanik dan Termal, 2019
This study is to determine the most suitable machining parameters to produce optimum surface roughness on turning operations using the Hurco TM20 CNC machine, ISCAR DNMG IC907 insert tool with aluminum 6061 as an object test material.
Diki Ismail Permana, Yayat Yayat
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Advanced Techniques for Monitoring, Simulation and Optimization of Machining Processes [PDF]

, 2011
In today’s manufacturing industry, pressure for productivity, higher quality and cost saving is heavier than ever. Surviving in today’s highly competitive world is not an easy task, contemporary technology updates and heavy investments are needed in ...
Keshari, Anupam
core  

Optimization of machining parameters in the manufacture of iron

Revista Produção Online, 2013
The surface roughness is one most important requirement in the machining process. The determination of machining parameters is an important stage in the manufacturing process and tool life.
Anderson Melo, Carla Schwengber ten Caten, Angelo M. O. Sant'Anna   +2 more
doaj   +1 more source