Results 21 to 30 of about 3,525 (160)

Alteration of subgingival microbiome in patients with type 2 diabetes induced by diabetes treatment. [PDF]

J Diabetes Investig
ABSTRACT Aims/Introduction Diabetes and periodontal disease, a bacterial infection involving the oral microbiome, have a bidirectional relationship. However, the relationship between poor glycemic control and the oral microbiome remains unclear. The aim of this study was to assess the direct effect of intensive glycemic control on the oral microbiome ...
Inoue M, Sakanaka A, Katakami N, Nishizawa H, Omori K, Taya N, Ishikawa A, Mayumi S, Takeuchi H, Amano A, Takeshita T, Fukusaki E, Shimomura I, Kuboniwa M.   +13 more
europepmc   +2 more sources

EFFECTS OF METABOLIC AND HAEMOSTATIC PARAMETERS ON DIABETIC ANGIOPATHY PROGRESSION

Российский кардиологический журнал, 2011
The parameters of carbohydrate, protein, lipid metabolism and haemostasis were analysed in patients with Type 1 and 2 diabetes mellitus (DM-1, DM-2), who demonstrated the progression of micro- and macroangiopathy over the five-year follow-up period ...
G. G. Petrik, S. A. Pavlishchuk
doaj   +1 more source

Effects of esaxerenone add-on therapy versus angiotensin II receptor blocker dose escalation on albuminuria and blood pressure in hypertensive patients with type 2 diabetes: An exploratory randomized study. [PDF]

J Diabetes Investig
ABSTRACT Aims Residual albuminuria remains a major clinical challenge in patients with type 2 diabetes mellitus and hypertension despite renin–angiotensin system inhibitor therapy. Esaxerenone, a selective nonsteroidal mineralocorticoid receptor antagonist, reduces albuminuria; however, its effects on oxidative stress remain unclear.
Ohara M, Omachi T, Takehana N, Fujikawa T, Osaka N, Irie S, Terasaki M, Mori Y, Matsui T, Yamagishi SI.   +9 more
europepmc   +2 more sources

Results from Cardiovascular Examination Do Not Predict Cerebrovascular Macroangiopathy: Data from a Prospective, Bicentric Cohort Study. [PDF]

J Clin Med
Background: There is a large overlap in the risk profiles and pathophysiologies of coronary artery disease (CAD) and cerebrovascular macroangiopathy. Therefore, this study aimed to analyse whether findings in CAD examination by coronary angiography or ...
Lepek J, Linnebank M, Bansemir L, Kloppe A.   +3 more
europepmc   +2 more sources

Topical Reappraisal of Molecular Pharmacological Approaches to Endothelial Dysfunction in Diabetes Mellitus Angiopathy

Current Issues in Molecular Biology, 2022
Diabetes mellitus (DM) is a frequent medical problem, affecting more than 4% of the population in most countries. In the context of diabetes, the vascular endothelium can play a crucial pathophysiological role. If a healthy endothelium—which is a dynamic
Constantin Munteanu, Mariana Rotariu, Marius-Alexandru Turnea, Aurelian Anghelescu, Irina Albadi, Gabriela Dogaru, Sînziana Calina Silișteanu, Elena Valentina Ionescu, Florentina Carmen Firan, Anca Mirela Ionescu, Carmen Oprea, Gelu Onose   +11 more
doaj   +1 more source

Small Fibre Neuropathy Is Associated With Impaired Vascular Endothelial Function in Patients With Type 2 Diabetes

Frontiers in Endocrinology, 2021
Diabetic polyneuropathy (DPN) and endothelial dysfunction are prevalent complications of diabetes mellitus. Currently, there are two non-invasive markers for endothelial dysfunction: flow-mediated dilation and reactive hyperaemia peripheral arterial ...
Akihiko Ando, Akihiko Ando, Akihiko Ando, Michiaki Miyamoto, Michiaki Miyamoto, Michiaki Miyamoto, Naoko Saito, Kazuhiko Kotani, Hideki Kamiya, Shun Ishibashi, Mitra Tavakoli   +10 more
doaj   +1 more source

Heterogeneity of DKD pathogenesis and amount of proteinuria: Dominancy of macroangiopathy or microangiopathy.

, 2022
Patients with modest proteinuria are more likely to be male and elderly. They tend to have an atrophic kidney and a history of atherosclerotic CVD (macroangiopathy).
Tatsufumi Oka (3134892), Takayuki Hamano (672525), Akira Suzuki (178307), Yoshitaka Isaka (410352), Yohei Doi (188766), Satoshi Yamaguchi (749948), Sachio Kajimoto (12152536), Yusuke Sakaguchi (1849051)   +7 more
core   +1 more source

Negative Pressure Wound Therapy as a Key Strategy in the Management of Severe Diabetic Foot Ulcers in Septic Frail Patients: A Case Series. [PDF]

Int Wound J
ABSTRACT Diabetes mellitus represents a major global health challenge, with over 537 million adults currently affected worldwide. Among its complications, diabetic foot ulcers remain a leading cause of morbidity, hospitalization and amputation, imposing a significant socioeconomic burden.
Pirski MI, Malerba S, Marano L, Kur M, Skokowski J, Świerblewski M.   +5 more
europepmc   +2 more sources

Vasculogenesis and angiogenesis in diabetes mellitus: novel pathogenetic concepts for treatment of vascular complications

Сахарный диабет, 2012
Hyperglycemia along with other metabolic disorders may disrupt the balance of pro- and antiangiogenic regulators, thus leading to a maladaptive formation of new blood vessels in the state of diabetes mellitus (DM).
Vladimir Iosifovich Konenkov, Vadim Valer'evich Klimontov   +1 more
doaj   +1 more source

Beneficial Effect of Sulodexide in Peripheral Diabetic Macroangiopathy - Radionuclide Estimation by Parameters of Planar Foot Bone Scintigraphy

Endocrinology Research and Practice, 2022
The aim of the study was to evaluate by parameters of planar foot bone scintigraphy the clinical efficacy of Sulodexide in the treatment of peripheral diabetic macro angiopathy Object of investigation were 48 patients with type 2 diabetes and peripheral ...
Hripsime A. Bohchelian, Anelia D. Klisarova, Lidia A. Koeva   +2 more
doaj   +2 more sources