Results 61 to 70 of about 3,525 (160)

Normothermic Regional Perfusion in Controlled Donation After Circulatory Death: Growing Evidence for Liver Transplantation

Clinical Transplantation, Volume 40, Issue 2, February 2026.
ABSTRACT Normothermic regional perfusion (NRP) has emerged as a pivotal strategy in controlled donation after circulatory death (cDCD) liver transplantation, mitigating ischemia‐reperfusion injury and improving graft outcomes. Compared to super rapid recovery (SRR), NRP significantly reduces rates of early allograft dysfunction, primary nonfunction ...
Daisuke Imai, Jacob Hallesy, Rohan Rathi, Christian Zbihley, Kush Savsani, Yuzuru Sambommatsu, Aamir A. Khan, Vinay Kumaran, David A. Bruno, Seung Duk Lee   +9 more
wiley   +1 more source

Renal Biomarkers as Predictors of Renal Damage in Patients With Type 2 Diabetes

BioMed Research International, Volume 2026, Issue 1, 2026.
Purpose Diabetes mellitus (DM) is a chronic metabolic disease of global health concern. Type 2 diabetes mellitus (T2DM) is characterized by varying degrees of insulin resistance and impaired insulin secretion and can lead to renal dysfunction. This study, therefore, evaluated the prognostic potential of renal biomarkers as predictors of kidney damage ...
Mohamed Osman Ali, DafaAllah Hassan Billal, GadAllah Modawe, Abdelhakam G. Tamomh, Ahmed Ibn Edriss, Yoel A. Klug   +5 more
wiley   +1 more source

Hyperhomocysteinemia and diabetic macroangiopathy: guilty or innocent bystander?. A literature review of the current dilemma

, 2007
Background: It is established from a large corpus of clinical studies that even moderately elevated plasma total homocysteine levels are associated with an increased risk for cardiovascular disease, in non-diabetic and in type 2 diabetic individuals ...
Hermans, Michel, Buysschaert, Martin, Preumont, Vanessa   +2 more
core   +1 more source

Spatial multiomics atlas reveals smooth muscle phenotypic transformation and metabolic reprogramming in diabetic macroangiopathy. [PDF]

Cardiovasc Diabetol
Background Diabetic macroangiopathy has been the main cause of death and disability in diabetic patients. The mechanisms underlying smooth muscle cell transformation and metabolic reprogramming other than abnormal glucose and lipid metabolism remain to ...
Qian Y, Xiong S, Li L, Sun Z, Zhang L, Yuan W, Cai H, Feng G, Wang X, Yao H, Gao Y, Guo L, Wang Z.   +12 more
europepmc   +2 more sources

Neonatal Outcomes Among Neonates of Women With and Without Type 1 Diabetes in Sweden From 2010 to 2022

Acta Paediatrica, Volume 114, Issue 12, Page 3191-3198, December 2025.
Neonatal outcomes among neonates of women with and without type 1 diabetes in Sweden from 2010 to 2022 by Goldberg A. et al. ABSTRACT Aim This register‐based study aimed to investigate differences in adverse neonatal outcomes between neonates born to mothers with and without type 1 diabetes in Sweden.
Alexandra Goldberg, Eva Wiberg‐Itzel, Joanna Tingström, Cecilia Ekéus   +3 more
wiley   +1 more source

Molecular mechanism for pancreatic β‐cell dysfunction and atherosclerosis and its therapeutic application: Importance of translational research bridging clinical practice and basic research

Journal of Diabetes Investigation, Volume 16, Issue 12, Page 2129-2136, December 2025.
ABSTRACT Introduction It is well‐known that when pancreatic β‐cells are chronically exposed to hyperglycemia under diabetic conditions, β‐cell function is gradually deteriorating. Although such phenomena were well‐known as β‐cell glucose toxicity in clinical practice, its molecular mechanism remained unknown.
Hideaki Kaneto, Tomohiko Kimura, Junpei Sanada, Yuichiro Iwamoto, Masashi Shimoda, Shuhei Nakanishi, Kohei Kaku   +6 more
wiley   +1 more source

Diabetic macroangiopathy: Pathogenetic insights and novel therapeutic approaches with focus on high glucose-mediated vascular damage

, 2018
Diabetic macroangiopathy - a specific form of accelerated atherosclerosis - is characterized by intra-plaque new vessel formation due to excessive/abnormal neovasculogenesis and angiogenesis, increased vascular permeability of the capillary vessels, and ...
De Caterina R., Piero Del Boccio, Madonna R., De Caterina, Raffaele, Geng, Yong-Jian, Madonna, Rosalinda, Rossi C., Geng Y. -J., Carmela Rita Balistreri, Balistreri, Carmela Rita, Yong-Jian Geng, Rosalinda Madonna, Pieragostino, Damiana, Raffaele De Caterina, Del Boccio P., Claudia Rossi, Damiana Pieragostino, Del Boccio, Piero, Rossi, Claudia, Pieragostino D., Balistreri C. R.   +20 more
core   +1 more source

sVCAM-1 levels in patients with type 2 diabetes mellitus with micro- and macrovascular complications.

Current Issues in Pharmacy and Medical Sciences, 2010
In the course of prolonged hyperglycemia changes similar to chronic inflammation occur in the organism, with increased phagocytic cell transition (neutrophils, monocytes) by the endothelium towards sites of inflammation.
Beata Wojtysiak-Duma, Agata Burska, Arleta Malecha-Jędraszek, Dariusz Duma, Helena Donica   +4 more
doaj  

Verification of Kumamoto Declaration 2013 and Glycemic Targets for Elderly Patients with Diabetes in Japan for prevention of diabetic complications: A retrospective longitudinal study using outpatient clinical data

Journal of Diabetes Investigation, 2019
Aims/Introduction The present study examined the association between the onset of micro‐ and macroangiopathy in type 2 diabetes mellitus patients and levels of glycated hemoglobin (HbA1c) described in the Evidence‐based Practice Guideline for the ...
Shuhei Nakanishi, Hidenori Hirukawa, Masashi Shimoda, Fuminori Tatsumi, Kenji Kohara, Atsushi Obata, Tomohiko Kimura, Seizo Okauchi, Tomoe Kinoshita, Junpei Sanada, Yoshiro Fushimi, Momoyo Nishioka, Akiko Mizoguchi, Tomoatsu Mune, Kohei Kaku, Hideaki Kaneto   +15 more
doaj   +1 more source

Аn overview of cardiovascular risks in patients with type 2 diabetes receiving glibenclamide

Медицинский совет, 2013
Diabetes mellitus type 2 is a chronic progressive disease which leads to specific vascular complications - microangiopathy and macroangiopathy. These complications are the reason of increased cardiovascular mortality, which is 4-5 times higher in ...
N. A. Chernikova, E. A. Ermakova
doaj   +1 more source