Results 71 to 80 of about 8,305 (169)

Formation of macrocyclic lactones in the Paternò–Büchi dimerization reaction

Beilstein Journal of Organic Chemistry, 2011
Furan-2-ylmethyl 2-oxoacetates 1a,b, in which the furan ring and the carbonyl moiety were embedded intramolecularly, were synthesized from commercially available furan-2-ylmethanol and their photochemical reaction (hν > 290 nm) was investigated.
Junya Arimura, Tsutomu Mizuta, Yoshikazu Hiraga, Manabu Abe   +3 more
doaj   +1 more source

A review of moxidectin vs. other macrocyclic lactones for prevention of heartworm disease in dogs with an appraisal of two commercial formulations

Frontiers in Veterinary Science
Macrocyclic lactones (MLs) are the only drug class currently licensed for heartworm disease prophylaxis. Macrocyclic lactones kill third- and fourth-stage larvae of Dirofilaria immitis, thus preventing the development of adult worms in dogs, which are ...
Kennedy Mwacalimba, Jenifer Sheehy, Christopher Adolph, Molly Savadelis, Kristina Kryda, Barbara Poulsen Nautrup   +5 more
doaj   +1 more source

Genetic polymorphism, constitutive expression and tissue localization of Dirofilaria immitis P-glycoprotein 11: a putative marker of macrocyclic lactone resistance. [PDF]

Parasit Vectors, 2022
Curry E, Prichard R, Lespine A.
europepmc   +1 more source

Dirofilaria immitis: Genotyping Randomly Selected European Clinical Samples and USA Laboratory Isolates with Molecular Markers Associated with Macrocyclic Lactone Susceptibility and Resistance. [PDF]

Pathogens, 2022
Curry E, Traversa D, Carretón E, Kramer L, Sager H, Young L, Prichard R.   +6 more
europepmc   +1 more source

Enigmazole C: A Cytotoxic Macrocyclic Lactone and Its Ring-Opened Derivatives from a New Species of Homophymia Sponge. [PDF]

J Nat Prod, 2022
Tarazona G, Fernández R, Pérez M, Millán RE, Jiménez C, Rodríguez J, Cuevas C.   +6 more
europepmc   +1 more source

Concern for Dirofilaria immitis and Macrocyclic Lactone Loss of Efficacy: Current Situation in the USA and Europe, and Future Scenarios. [PDF]

Pathogens, 2021
Diakou A, Prichard RK.
europepmc   +1 more source

Tri-Model Therapy: Combining Macrocyclic Lactone, Piperazine Derivative and Herbal Preparation in Treating Humpsore in Cattle. [PDF]

Vet Sci, 2021
Ponraj P, De AK, Mondal S, Ravi SK, Sawhney S, Sarkar G, Bera AK, Malakar D, Kumar A, Singh LB, Ahmed SZ, Muniswamy K, Jerard BA, Bhattacharya D.   +13 more
europepmc   +1 more source

Macrocyclic lactones inhibit nasopharyngeal carcinoma cells proliferation through PAK1 inhibition and reduce in vivo tumor growth

Drug Design, Development and Therapy, 2018
Franck Gallardo,1 Bernard Mariamé,2 Remi Gence,3 Anne-Francoise Tilkin-Mariamé4 1NeoVirTech, SAS, Institut for Advanced Technology in Life Science (ITAV), Toulouse, France; 2ITAV USR3505 CNRS/LBME, UMR 5099 CNRS, Toulouse, France; 3INSERM ...
Gallardo F, Mariamé B, Gence R, Tilkin-Mariamé AF   +3 more
doaj  

Pharyngeal Pumping and Tissue-Specific Transgenic P-Glycoprotein Expression Influence Macrocyclic Lactone Susceptibility in Caenorhabditis elegans. [PDF]

Pharmaceuticals (Basel), 2021
Gerhard AP, Krücken J, Neveu C, Charvet CL, Harmache A, von Samson-Himmelstjerna G.   +5 more
europepmc   +1 more source

Secretory microRNA Profiles of Third- and Fourth-Stage Dirofilaria immitis Larvae with Different Macrocyclic Lactone Susceptibility: In Search of Biomarkers for Early Detection of Infection. [PDF]

Pathogens, 2021
Tritten L, Burkman EJ, Clark T, Verocai GG.   +3 more
europepmc   +1 more source