Results 81 to 90 of about 113,437 (249)
PLoS ONE, 2016 Nematode parasites may be controlled with drugs, but their regular application has given rise to concerns about the development of resistance. Drug combinations may be more effective than single drugs and delay the onset of resistance.
M. Abongwa +3 more
semanticscholar +1 more source
Equine Veterinary Education, EarlyView.Summary Background The association between tapeworm infection and equine colic is established, but gaps remain regarding specific colic types. Objectives To assess the relationship between tapeworm test results and equine colic types: The study aimed to determine if ileocaecal disorders (IC) are more frequently associated with Anoplocephala spp ...
K. L. Adamasky +9 more
wiley +1 more source
Jurnal Ternak Tropika, 2019 Cacing nematoda gastrointestinal merupakan parasit yang memiliki peran penting pada ruminansia di negara tropis maupun subtropis. Nematoda tersebut memicu berbagai masalah kesehatan dan dapat mengakibatkan penurunan produksi karena menghambat pertumbuan,
Yanuartono Yanuartono +4 more
doaj +1 more source
Frontiers in Veterinary Science, 2020 Canine heartworm disease is a life-threatening disease caused by Dirofilaria immitis and is prevalent in Brazil. The standard drug for its treatment, melarsomine dihydrochloride, is a fast-killing organic arsenical chemotherapeutic agent not approved in ...
Bruno Alberigi +4 more
doaj +1 more source
Proteasome inhibitors: recent advances and new perspectives in medicinal chemistry [PDF]
, 2010 International audienceThe search for proteasome inhibitors began fifteen years ago. These inhibitors proved to be powerful tools for investigating many important cellular processes regulated by the ubiquitinproteasome pathway.
Génin, Emilie +2 more
core +3 more sources
Treatment of MDR1 Mutant Dogs with Macrocyclic Lactones [PDF]
Current Pharmaceutical Biotechnology, 2012 P-glycoprotein, encoded by the multidrug resistance gene MDR1, is an ATP-driven drug efflux pump which is highly expressed at the blood-brain barrier of vertebrates. Drug efflux of macrocyclic lactones by P-glycoprotein is highly relevant for the therapeutic safety of macrocyclic lactones, as thereby GABA-gated chloride channels, which are confined to ...
Geyer, Joachim, Janko, Christina
openaire +2 more sources
Journal of Veterinary Pharmacology and Therapeutics, EarlyView.ABSTRACT The ATP‐binding cassette transporter MDR1 P‐glycoprotein (syn. ABCB1) is an efflux carrier at the cell membrane that regulates drug absorption, distribution, and elimination. At the blood–brain barrier, MDR1 restricts brain entry of potentially neurotoxic drugs, such as ivermectin. In dogs and cats, MDR1 (syn.
Lisa Siegl +6 more
wiley +1 more source
Anthelmintic resistance of gastrointestinal cattle nematodes [PDF]
, 2013 Anthelmintic resistance of parasites in small ruminants, cattle and horses is increasing worldwide as a consequence of the over usage of the currently available products.
Claerebout, Edwin +2 more
core
First report of anthelmintic resistance in Haemonchus contortus in alpacas in Australia [PDF]
, 2013 BACKGROUND: Parasitic nematodes can cause substantial clinical and subclinical problems in alpacas and anthelmintics are regularly used to control parasitic nematodes in alpacas.
Abdul Jabbar +3 more
core +1 more source
Efficacy of imidacloprid 10%/moxidectin 1% spot-on formulation (Advocate®) in the prevention and treatment of feline aelurostrongylosis [PDF]
, 2020 Background: In three randomized, controlled laboratory efficacy studies, the efficacy in the prevention of patent infections of a topical combination of imidacloprid 10%/moxidectin 1% (Advocate® spot-on formulation for cats, Bayer Animal Health GmbH ...
Blazejak, Katrin +9 more
core +1 more source