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Atypical Presentation of VEXAS Syndrome Amid Coexisting Comorbidities: Diagnosis by High Depth Targeted Sequencing. [PDF]
Int J Rheum DisChidambaram M +4 more
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Red Cell Indices-Based Morphological Patterns of Anemia and Associated Factors Among Adults With Diabetes Mellitus: A Cross-Sectional Study at Mubende Regional Referral Hospital, Uganda. [PDF]
AnemiaKahie FD +11 more
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Macrocytic anemia induced via oral administration of toxic dose of acetaminophen
GSC Biological and Pharmaceutical Sciences, 2022 The abuse of Acetaminophen (over-the-counter drug) is rapidly increasing globally, thus inducing physiological alterations and toxicity. In this study, it was hypothesized that overdose of acetaminophen may induce certain type of anemia; hence the type ...
Osah Martins Onwuka
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Evaluation of Macrocytic Anemias
Seminars in Hematology, 2015Macrocytic anemia, defined as a mean cell volume (MCV) ≥100 fL in adults, has a narrow differential diagnosis that requires evaluation of the peripheral blood smear as well as additional laboratory testing taken in conjunction with clinical information that includes patient history and physical examination findings.
Ralph, Green, Denis M, Dwyre
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Laboratory Medicine, 1990
Megaloblastic anemias result from processes that disrupt DNA synthesis. The condition is usually acquired, with medications, cobalamin, or folate deficiency being common precipitating factors. Many patients with cobalamin or folate deficiency will present with hematologic abnormalities, such as anemia or pancytopenia, along with macroovalocytes and ...
Steven Scates, John Glaspy
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Megaloblastic anemias result from processes that disrupt DNA synthesis. The condition is usually acquired, with medications, cobalamin, or folate deficiency being common precipitating factors. Many patients with cobalamin or folate deficiency will present with hematologic abnormalities, such as anemia or pancytopenia, along with macroovalocytes and ...
Steven Scates, John Glaspy
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Postgraduate Medicine, 1977
Macrocytic anemias are not uncommon in clinical practice, and precise etiologic diagnosis is mandatory for proper management. Measurement of serum levels of vitamin B12 and folic acid may obviate the need for extensive diagnostic studies.
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Macrocytic anemias are not uncommon in clinical practice, and precise etiologic diagnosis is mandatory for proper management. Measurement of serum levels of vitamin B12 and folic acid may obviate the need for extensive diagnostic studies.
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Current Opinion in Hematology
Purpose of review Over the last century, the diseases associated with macrocytic anemia have been changing with more patients currently having hematological diseases including malignancies and myelodysplastic syndrome. The intracellular mechanisms underlying the development of anemia with macrocytosis can help in understanding ...
Mark J, Koury, Daniel J, Hausrath
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Purpose of review Over the last century, the diseases associated with macrocytic anemia have been changing with more patients currently having hematological diseases including malignancies and myelodysplastic syndrome. The intracellular mechanisms underlying the development of anemia with macrocytosis can help in understanding ...
Mark J, Koury, Daniel J, Hausrath
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TREATMENT OF MACROCYTIC ANEMIAS
Archives of Internal Medicine, 1955ANEMIAS characterized by large erythrocytes (MCV > 95) are usually caused by lack of one of the erythrocyte maturation factors, vitamin B12or folinic acid. Under these circumstances the young erythrocytes in the bone marrow are megaloblastic and maturation of myeloid elements and megakaryocytes is bizarre.
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