Results 111 to 120 of about 86,656 (282)

Macrolide resistance determinants among isolates from carriers in Central Greece [PDF]

, 2012
Background: We sought to characterize the temporal trends in nasopharyngeal carriage of macrolide-resistant pneumococci during a period with increased heptavalent pneumococcal conjugate vaccine (PCV7) coverage in Central Greece.
Grivea, I. N., Tsantouli, A. G., Alexia Sourla, Denise C Chryssanthopoulou, Syrogiannopoulos, G. A., George A Syrogiannopoulos, Ntokou, E., Sourla, A., Eleni Ntokou, Alexandra G Tsantouli, Chryssanthopoulou, D. C., Ioanna N Grivea   +11 more
core   +2 more sources

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

Macrolide resistance due to erm(55)

Antimicrobial resistance (AMR) is a global threat. The identification and characterization of novel resistance genes is integral to AMR surveillance.
Andrew D. S. Cameron, Danae M. Suchan, Omar M. El-Halfawy, David C. Alexander, Joshua M. E. Adams, Richard J. Wallace Jr., Barbara A. Brown-Elliott, Sean D. Workman, Tayah Farquhar   +8 more
core   +1 more source

Infectious bacterial keratitis management in a Swedish region: Risk factors, treatment and time‐to‐resolution

Acta Ophthalmologica, EarlyView.
Abstract Purpose To report treatment patterns, time‐to‐resolution (TTR) and aetiologies of bacterial keratitis (BK) infections treated in a specialized hospital‐based cornea clinic in Sweden. Methods Retrospective study based on electronic health records screened during the period 2010–2019. The study included only culture‐confirmed cases of BK.
Jenny Roth, Antonio Filipe Macedo, Sofia Somajo, Lukas Tannerfeldt, Baris Toprak, Neil Lagali   +5 more
wiley   +1 more source

Efficacy and safety of topical macrolides versus systemic tetracyclines for meibomian gland dysfunction–a systematic review and meta‐analysis

Acta Ophthalmologica, EarlyView.
Abstract Purpose To review the efficacy and safety of oral doxycycline antibiotics versus topical macrolides in the treatment of meibomian gland dysfunction (MGD). Design Systematic review and meta‐analysis. Methods A comprehensive search of PubMed, Scopus, Embase, and ClinicalTrials.gov through December 2024 identified randomised controlled trials ...
Margarita Safir, Clara C. Chan, Joshua C. Teichman, Itamar Arbel, Ruth Lapid‐Gortzak, Camiel J. F. Boon, Michael Mimouni, Dror Ben Ephraim Noyman   +7 more
wiley   +1 more source

Nasopharyngeal carriage and macrolide resistance in Indigenous children with bronchiectasis randomized to long-term azithromycin or placebo

, 2015
Although long-term azithromycin decreases exacerbation frequency in bronchiectasis, increased macrolide resistance is concerning. We investigated macrolide resistance determinants in a secondary analysis of a multicenter randomized controlled trial ...
Smith-Vaughan, HC, Valery, PC, Morris, PS, Valery, Patricia C., Grimwood, K., Byrnes, CA, Leach, A J, Smith-Vaughan, H C, Smith-Vaughan, Heidi, Torzillo, P. J., Grimwood, Keith, Torzillo, Paul J., Chang, A B, Byrnes, C A, Leach, Amanda, Byrnes, Catherine Ann, Cheng, A C, Leach, A. J., Hare, K. M., Chatfield, M. D., Byrnes, C. A., Morris, Peter, Cheng, Allen C., Chatfield, Mark, Chatfield, MD, Morris, P. S., Hare, Kim, Chang, A. B., Cheng, A. C., Cheng, Allen, Chang, Anne B., Torzillo, PJ, Leach, AJ, Valery, Patricia, Valery, P C, Hare, Kim M., Hare, K M, Torzillo, Paul, Chatfield, M D, Chang, AB, Hare, KM, Cheng, AC, Smith-Vaughan, H. C., Byrnes, Catherine, Morris, P S, Torzillo, P J, Leach, Amanda Jane, Valery, P. C., Grimwood, K   +48 more
core   +1 more source

Antimicrobial Resistance in Children With Bloodstream Infections: A Population‐Based Study in Stockholm, Sweden

Acta Paediatrica, EarlyView.
ABSTRACT Aim We retrospectively evaluated trends in antimicrobial resistance (AMR) in paediatric bloodstream infections and assessed changes in antimicrobial prescription patterns over a 20‐year period. Methods We analysed positive blood cultures from children admitted with suspected serious infection between 1998 and 2018.
Joachim Luthander, Rutger Bennet, Per Nydert, Margareta Eriksson, Christian G. Giske, Anna Nilsson   +5 more
wiley   +1 more source

A Real‐World Controlled Multicentre Study Evaluating the Association Between Benralizumab Therapy and Major Outcomes in Severe Asthma

Clinical &Experimental Allergy, EarlyView.
Among patients with severe eosinophilic asthma, benralizumab was associated with greater improvements in asthma outcomes—such as improved asthma control, quality of life and remission rates—compared to biologic‐naïve patients. ABSTRACT Background Real‐world data on benralizumab in patients with severe eosinophilic asthma–while controlling for ...
Dennis Thomas, Vanessa M. McDonald, Gijo Thomas, Joy Lee, Li Ping Chung, Matthew Peters, Shakti D. Shukla, Yuto Hamada, Erin S. Harvey, Michael Fricker, Hayley See, Rejoy Sabin Thomas, Claude S. Farah, Andrew Gillman, Constance H. Katelaris, Gregory P. Katsoulotos, David Langton, Peter G. Middleton, Paul Reynolds, Janet Rimmer, Francis Thien, Stephen Vincent, John W. Upham, Peter G. Gibson   +23 more
wiley   +1 more source

Inactivation of a purine biosynthesis repressor promotes ribosome synthesis to overcome antibiotic stress

mBio
Macrolide, lincosamide, and streptogramin (MLS) antibiotics are structurally distinct molecules that inhibit protein synthesis by binding overlapping sites within the 23S rRNA of bacterial ribosomes. The clinical utility of MLS antibiotics has diminished
Alexandre Le Scornet, Yongjun Tan, Dapeng Zhang, Jue D. Wang, Mee-Ngan F. Yap   +4 more
doaj   +1 more source

Antimicrobial drug use and macrolide-resistant **Streptococcus pyogenes**, Belgium

, 2012
: In Belgium, decreasing macrolide, lincosamide, streptogramins B, and tetracycline use during 19972007 correlated significantly with decreasing macrolide-resistant Streptococcus pyogenes during 19992009.
Samuel Coenen, Surbhi Malhotra-Kumar, Hens, Niel, van Heirstraeten, Liesbet, Liesbet Van Heirstraeten, Christine Lammens, Herman Goossens, Malhotra-Kumar, Surbhi, Coenen, Samuel, Goossens, Herman, Lammens, Christine, Malhotra, Surbhi, Niel Hens   +12 more
core   +1 more source