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Journal of Clinical Medicine, 2021 We have found that early corticosteroid therapy was effective for reducing morbidity during five Korea-wide epidemics. We evaluated the clinical and laboratory parameters of 56 children who received early corticosteroid treatment for pneumonia that was ...
Kyung-Yil Lee +2 more
exaly +2 more sources
Evaluation of Lightmix Mycoplasma macrolide assay for detection of macrolide-resistant Mycoplasma pneumoniae in pneumonia patients [PDF]
Clinical Microbiology and Infection, 2019 OBJECTIVES Rapid detection of macrolide resistance-associated mutations in Mycoplasma pneumoniae is crucial for effective antimicrobial treatment. We evaluated the Lightmix Mycoplasma macrolide assay for the detection of point mutations at nucleotide ...
P M Keller
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Expert Opinion on Investigational Drugs, 2002
Erythromycin, which was introduced over 50 years ago, was the first macrolide to be used clinically. "New" macrolides, for the treatment of patients with various infectious diseases, were not clinically introduced until 40 years later. The pharmacokinetic and adverse events profile of erythromycin initially limited its use to an alternative agent for ...
Joseph M, Blondeau +3 more
openaire +2 more sources
Erythromycin, which was introduced over 50 years ago, was the first macrolide to be used clinically. "New" macrolides, for the treatment of patients with various infectious diseases, were not clinically introduced until 40 years later. The pharmacokinetic and adverse events profile of erythromycin initially limited its use to an alternative agent for ...
Joseph M, Blondeau +3 more
openaire +2 more sources
Clinics in Dermatology, 2003
I n 1952, erythromycin was isolated from the metabolic products of a strain of Streptomyces erythreus obtained from Philippine soil. Originally, erythromycin (Fig 1) was used as an alternative to penicillin because of its activity against Gram-positive organisms, such as staphylococci, pneumococci, streptococci, mycoplasma, legionella, campylobacter ...
Noah S, Scheinfeld +3 more
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I n 1952, erythromycin was isolated from the metabolic products of a strain of Streptomyces erythreus obtained from Philippine soil. Originally, erythromycin (Fig 1) was used as an alternative to penicillin because of its activity against Gram-positive organisms, such as staphylococci, pneumococci, streptococci, mycoplasma, legionella, campylobacter ...
Noah S, Scheinfeld +3 more
openaire +3 more sources
Veterinary Dermatology, 1999
Macrolides and lincosamides are first choice bacteriostatic antibiotics used in veterinary dermatology. The main antibiotics in these classes are erythromycin, lincomycin, clindamycin and tylosin. They are well absorbed if given orally and are able to penetrate well into infected skin.
C, Noli, D, Boothe
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Macrolides and lincosamides are first choice bacteriostatic antibiotics used in veterinary dermatology. The main antibiotics in these classes are erythromycin, lincomycin, clindamycin and tylosin. They are well absorbed if given orally and are able to penetrate well into infected skin.
C, Noli, D, Boothe
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Current Pharmaceutical Design, 2008
Macrolides are characterised by their basic structure which is made up of a lactonic cycle with 2 osidic chains. They are classified according to the number of carbon atoms in the cycle : 14 membered macrolides (erythromicin, roxithromycin, dirithromycin, clarithromycin), 15 membered (azithromycin) and 16 membered (spiramycin, josamycin, midecamycin ...
Luis, Araújo, Pascal, Demoly
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Macrolides are characterised by their basic structure which is made up of a lactonic cycle with 2 osidic chains. They are classified according to the number of carbon atoms in the cycle : 14 membered macrolides (erythromicin, roxithromycin, dirithromycin, clarithromycin), 15 membered (azithromycin) and 16 membered (spiramycin, josamycin, midecamycin ...
Luis, Araújo, Pascal, Demoly
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Drug Resistance Updates, 1998
The macrolides have evolved through four chemical generations since erythromycin became available for clinical use in 1952. The first generation, the 14-membered ring macrolide erythromycin, induced resistance and was replaced by the second generation 16-membered ring macrolides which did not.
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The macrolides have evolved through four chemical generations since erythromycin became available for clinical use in 1952. The first generation, the 14-membered ring macrolide erythromycin, induced resistance and was replaced by the second generation 16-membered ring macrolides which did not.
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The Indian Journal of Pediatrics, 1998
This article is an extensive review of current information available on the macrolide antibiotics. This includes antimicrobial spectrum, pharmacology, complications and side effects, and pediatric use of these drugs. These are important antibiotics, but careful selection of patients must be made and the physician must be alert for evidence of drug-drug
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This article is an extensive review of current information available on the macrolide antibiotics. This includes antimicrobial spectrum, pharmacology, complications and side effects, and pediatric use of these drugs. These are important antibiotics, but careful selection of patients must be made and the physician must be alert for evidence of drug-drug
openaire +2 more sources