Results 31 to 40 of about 2,246,897 (273)
An Overview of Macrolide Resistance in Streptococci: Prevalence, Mobile Elements and Dynamics
, 2022 Streptococcal infections are usually treated with beta-lactam antibiotics, but, in case of allergic patients or reduced antibiotic susceptibility, macrolides and fluoroquinolones are the main alternatives.
Berbel, Dàmaris +9 more
core +1 more source
International Journal of Infectious Diseases, 2019 Bystander selection has been shown to result in strong population-level correlations between the level of antimicrobial consumption in the general population and resistance to that antimicrobial or similar antimicrobials in a range of bacteria.
Chris Kenyon
doaj +1 more source
Noncanonical Peloruside A Biosynthesis by an Uncultivated Verrucomicrobiota Symbiont
Angewandte Chemie, EarlyView.Noncanonical biochemistry of the peloruside PKS characterized in this work, comprising double bond generation by a noncanonical tridomain (blue), acetyl‐CoA recycling (orange), and proofreading systems (purple and yellow). The Z‐double bond is installed by TEB1 through O‐acetylation and acetate elimination. The acyl ligase PelB (AL, orange) selectively
Amy E. Fraley +11 more
wiley +2 more sources
BMC Infectious Diseases, 2017 Background With the emergence of macrolide resistance, concerns about the efficacy of macrolides for the treatment of Mycoplasma pneumoniae (MP) pneumonia in children have been raised.
In Ae Yoon +12 more
doaj +1 more source
Effects of macrolides on pneumolysin of macrolide-resistantStreptococcus pneumoniae [PDF]
European Respiratory Journal, 2006 To clarify the discrepancy between increasing resistance and conservative clinical effects of macrolides on macrolide-resistantStreptococcus pneumoniae, the authors evaluated the effects of sub-minimum inhibitory concentrations of macrolides on pneumolysin.In vitro,S.
Y, Fukuda +9 more
openaire +2 more sources
, 2021 Staphylococcus aureus (S.aureus) is a prevalent organism causing infections in the community and hospital. A variety of antibiotics are used, including the Macrolide-Lincosamide-StreptograminB (MLSB) family of antibiotics in which clindamycin is the ...
Pradeep Madala Sobhana Surya +3 more
core +1 more source
Phenotypes and genotypes of macrolide-resistant Streptococcus pneumoniae in Serbia [PDF]
Archives of Biological Sciences, 2014 Although macrolides are widely used for treating pneumococcal infections, an increase in macrolide resistance might compromise their use. The objective of this study was to determine the prevalence of macrolide-resistant phenotypes and genotypes
Hadnađev Mirjana +6 more
doaj +1 more source
Nomenclature for Macrolide and Macrolide-Lincosamide-Streptogramin B Resistance Determinants [PDF]
Antimicrobial Agents and Chemotherapy, 1999 Macrolides are composed of 14 (erythromycin and clarithromycin)-, 15 (azithromycin)-, or 16 (josamycin, spiramycin, and tylosin)-membered lactones to which are attached amino and/or neutral sugars via glycosidic bonds. Erythromycin was introduced in 1952 as the first macrolide antibiotic.
M C, Roberts +5 more
openaire +2 more sources
CAQ Corner: Basic concepts of transplant immunology
, 2022 Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
High-Level Macrolide Resistance Due to the Mega Element [mef(E)/mel] in Streptococcus pneumoniae
Frontiers in Microbiology, 2019 Transferable genetic elements conferring macrolide resistance in Streptococcus pneumoniae can encode the efflux pump and ribosomal protection protein, mef(E)/mel, in an operon of the macrolide efflux genetic assembly (Mega) element- or induce ribosomal ...
Max R. Schroeder +6 more
doaj +1 more source