Results 181 to 190 of about 56,953 (293)

Antibacterial consumption in four paediatric inpatient facilities in Sri Lanka in 2023: a cross-sectional descriptive study. [PDF]

BMJ Open
Sri Ranganathan S, Yasawardene PC, Senadheera S, Wijayawardena MAM, Jayasundara RJMKA, Perera TMR, Dissanayake R, Karunaratne KW.   +7 more
europepmc   +1 more source

Synthetic Strategies for the Construction of Cyclobutane‐Fused Heterocycles

European Journal of Organic Chemistry, Volume 29, Issue 40, 27 October 2026.
Cyclobutane‐fused heterocycles are important motifs commonly present in bioactive compounds, recognized for their rigid 3D structures that confer unique properties. However, synthesizing these compounds remains challenging. This review discusses current methods for their synthesis, such as photochemical, metal‐catalyzed, and Lewis acid‐mediated [2 + 2]
Michela Vargiu, Mauro Uras, Angelo Frongia   +2 more
wiley   +1 more source

Appropriateness of outpatient antibiotic prescriptions in acute-care hospitals in Japan: a cross-sectional study from 2016-22. [PDF]

JAC Antimicrob Resist
Kohei K, Hiroshi M, Shimon K, Yuka T, Naoki M, Nobuaki M, Tomoaki H, Kosaku U, Daisuke T, Satoshi I, Toshitaka W, Susumu I, Yoshikazu M, Shoko S, Ryoko F, Kenji A, Kimiyasu M, Hiroki K, Jun K, Hisanori H, Takashi A, Asami H, Maiko I, Tetsushi A, Naoka I, Hiroya M, Keisuke S, Hiroshi H, Takuya G, Masanobu T, Daiki F, Hideya S, Hiroaki T, Yukiko N, Tomonori N, Toshihiko O, Atsushi H, Tetsuya Y.   +37 more
europepmc   +1 more source

Regioselective Aldol Reactions Directed by Charge and Orbital Effects in Cyclic Germyl Dienolates: Synthesis of Three Distinct Regio‐ and Stereoisomers

Chemistry – A European Journal, Volume 32, Issue 38, 13 October 2026.
Charge and orbital control represent fundamental principles in organic chemistry. In this study, these principles are applied to the aldol reactions of a cyclic Ge‐dienolate. By systematically tuning the charge and orbital distributions of the Ge‐dienolates and their aldehyde reaction partners, regio‐ and stereoselective access to three distinct aldol ...
Taishi Nojima, Akihito Konishi, Makoto Yasuda   +2 more
wiley   +1 more source

Antiviral Activity of Polyene Macrolides Against Newcastle Disease Virus: Computational and Experimental Insights. [PDF]

Molecules
Mukhametkaliyev A, Bogoyavlenskiy A, Alexyuk P, Alexyuk M, Sokolova N, Moldakhanov Y, Akanova K, Temirbayeva A, Mussoyev A, Śmietanka K, Berezin V.   +10 more
europepmc   +1 more source

A Comprehensive Microbial Gene Catalog of the Human Airway Microbiome Across Anatomical Sites and Geographic Regions

Advanced Science, Volume 13, Issue 56, 9 October 2026.
An integrated Human Airway Microbiome Gene Catalog (iHAMGC) is constructed from 12,273 metagenomic airway samples, providing a high‐resolution reference of respiratory microbial genes. The catalog enables systematic exploration of taxonomic and functional variation across airway niches and geographic regions, revealing site‐specific and region ...
Qing Zhang, Dashu Li, Bo Liu, Yue Zhang, Min Li, Ruochun Guo, Yawen Ni, Shibin Chen, Biao Ni, Lijie Qiu, Guorui Xing, He Dong, Qiulong Yan, Shenghui Li, Xiaohui Zou, Bin Cao   +15 more
wiley   +1 more source

Mass Flux Analysis Reveals the Presence and Fate of Antimicrobials in Hospital Effluent, Wastewater Treatment Plant, and River Environments. [PDF]

Antibiotics (Basel)
Azuma T, Usui M, Hasei T, Hayashi T.
europepmc   +1 more source

The effect of mild and moderate hepatic impairment on the pharmacokinetics, safety and tolerability of balcinrenone

British Journal of Clinical Pharmacology, Volume 92, Issue 10, Page 3656-3665, October 2026.
Abstract Aim Balcinrenone (previously AZD9977) is a novel selective non‐steroidal mineralocorticoid receptor antagonist (MRA) with a differential mechanism of action relative to approved MRAs. The aim of this trial was to assess the pharmacokinetics, safety and tolerability of balcinrenone in participants with mild and moderate hepatic impairment ...
Anna L. Eriksson, Deeyen Karsanji, Bonifride Tuyishimire, Joanna Parkinson, Maria Heijer, Tadeusz Pawlik, Judith Hartleib‐Geschwindner, Maria Leonsson‐Zachrisson, Hans Ericsson   +8 more
wiley   +1 more source

Vancomycin-Resistant, Thermotolerant <i>Enterococcus faecalis</i> and <i>Enterococcus faecium</i> in Ready-to-Eat Beef Luncheon and Sausage. [PDF]

Foods
Sallam SA, Imre M, Abd-Elghany SM, Imre K, Sallam KI.   +4 more
europepmc   +1 more source

LC‐MS‐Based Annotation of Bioactive Metabolites From Streptomyces fimicarius‐ghR Against the Common Scab Pathogen Using Molecular Networking

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
EtOAc extract of Streptomyces fimicarius‐ghR exhibited inhibitory activity against Streptomyces sp. FG1(MIC: 0.3 mg/mL). The LC‐QTOF‐ESI‐MS/MS analysis of the extract, followed by data analysis through molecular networking (GNPS), led to the annotation of mycosubtilins, cyclic surfactins, and linear surfactins.
Maryam Ramezani‐Moghadam, Sareh Baghaee‐Ravari, Abolghasem Danesh, Mohsen Taghavi, Karel Nesměrák, Martin Štícha, Maryam Akaberi   +6 more
wiley   +1 more source