Results 71 to 80 of about 2,713 (253)

Entropic stabilization of the folded states of RNA due to macromolecular crowding [PDF]

open access: yes, 2013
We review the effects of macromolecular crowding on the folding of RNA by considering the simplest scenario when excluded volume interactions between crowding particles and RNA dominate. Using human telomerase enzyme as an example, we discuss how crowding can alter the equilibrium between pseudoknot and hairpin states of the same RNA molecule - a key ...
arxiv   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

open access: yesMolecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang   +8 more
wiley   +1 more source

Atmospheric HULIS: How humic-like are they? A comprehensive and critical review [PDF]

open access: yesAtmospheric Chemistry and Physics, 2006
A class of organic molecules extracted from atmospheric aerosol particles and isolated from fog and cloud water has been termed HUmic-LIke Substances (HULIS) due to a certain resemblance to terrestrial and aquatic humic and fulvic acids.
E. R. Graber, Y. Rudich
doaj  

Discrete-time model for a substance motion in a channel of a network. Application to a human migration channel [PDF]

open access: yesarXiv, 2018
We discuss a discrete-time model for motion of substance in a channel of a network. For the case of stationary motion of the substance and for the case of time-independent values of the parameters of the model we obtain a new class of statistical distributions that describe the distribution of the substance along the nodes of the channel.
arxiv  

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

Probability distribution connected to stationary flow of substance in a channel of network containing finite number of arms [PDF]

open access: yesarXiv, 2020
We discuss a channel consisting of nodes of a network and lines which connect these nodes and form ways for motion of a substance through the channel. We study stationary flow of substance for channel which arms contain finite number of nodes each and obtain probability distribution for substance in arms of this channel.
arxiv  

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

open access: yesMolecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang   +10 more
wiley   +1 more source

Temperature dependency of VOCs release characteristics of asphalt materials under varying test conditions

open access: yesJournal of Traffic and Transportation Engineering (English ed. Online), 2022
Asphalt pavement is increasingly used in paving and roofing. However, the release of volatile organic compounds (VOCs) from asphalt harm both the environment and humans.
Xiwen Chang   +4 more
doaj  

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

open access: yesMolecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park   +6 more
wiley   +1 more source

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