Results 31 to 40 of about 925,934 (312)

Chain entanglement enhanced strong and tough wool keratin/albumin fibers for bioabsorbable and immunocompatible surgical sutures

Nature Communications
High-performance fibers derived from non-silk proteins have garnered significant interest in biomedical applications because of their high accessibility and biocompatibility.
Haonan He, Xianchi Zhou, Yuxian Lai, Rouye Wang, Hongye Hao, Xintian Shen, Peng Zhang, Jian Ji   +7 more
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Comparison of immunomodulatory activity of polysaccharides and soluble dietary fibers and adsorption capacities of insoluble dietary fibers extracted from Lentinus edodes stipes

Food Production, Processing and Nutrition
Stipes are the major waste from the processing of Lentinus edodes. To make full use of L. edodes stipes (LES), different fractions of LES polysaccharides (LESPs) were first obtained by water extraction and gradient ethanol precipitation.
Yujiao Sun, Baobao Li, Yuanye Xue, Jiankang Wang, Bingbing Miao, Yang Liu, Yanjun Li, Yungang Cao, Dawei Chang   +8 more
doaj   +1 more source

Synthesis, Herbicidal Activity, and Molecular Mode of Action Evaluation of Novel Quinazolinone—Phenoxypropionate Hybrids Containing a Diester Moiety

Agronomy
To develop aryloxyphenoxypropionate herbicides with novel structure and improved activity, a total of twenty-eight novel quinazolinone–phenoxypropionate derivatives containing a diester moiety were designed and synthesized.
Shumin Wang, Na Li, Shibo Han, Shuyue Fu, Ke Chen, Wenjing Cheng, Kang Lei   +6 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Macromolecule Orientation in Nanofibers

Nanomaterials, 2018
Electrospinning is now commercially used for the fabrication of nano/micro fibers. Compared with spider dragline silk, artificial fibers have poor mechanical properties.
Dan Tian, Chun-Hui He, Ji-Huan He
doaj   +1 more source

Macromolecular organic acids in the Murchison meteorite [PDF]

, 2005
This study has detected bound organic acids within the Murchison meteorite organic macromolecule. Benzoic acid was the most abundant compound; other abundant compounds include C1 and C2 benzoic acids.
Gilmour, I., Sephton, M. A., Watson, J. S.   +2 more
core  

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Differential scanning calorimetry: An invaluable tool for a detailed thermodynamic characterization of macromolecules and their interactions

Journal of Pharmacy and Bioallied Sciences, 2011
Differential Scanning Calorimetry (DSC) is a highly sensitive technique to study the thermotropic properties of many different biological macromolecules and extracts.
Michael H Chiu, Elmar J Prenner
doaj   +1 more source

Detachment of semiflexible polymer chains from a substrate - a Molecular Dynamics investigation

, 2014
Using Molecular Dynamics simulations, we study the force-induced detachment of a coarse-grained model polymer chain from an adhesive substrate. One of the chain ends is thereby pulled at constant speed off the attractive substrate and the resulting saw ...
Erbas, A., Milchev, A., Paturej, J., Rostiashvili, V. G.   +3 more
core   +1 more source