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Recent Advances in Exosome-Based Therapeutic Strategies for Acute Lung Injury: Mechanisms and Translational Advances. [PDF]
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Annual Review of Physiology, 2017
Macrophage polarization refers to how macrophages have been activated at a given point in space and time. Polarization is not fixed, as macrophages are sufficiently plastic to integrate multiple signals, such as those from microbes, damaged tissues, and the normal tissue environment.
Peter J Murray
exaly +3 more sources
Macrophage polarization refers to how macrophages have been activated at a given point in space and time. Polarization is not fixed, as macrophages are sufficiently plastic to integrate multiple signals, such as those from microbes, damaged tissues, and the normal tissue environment.
Peter J Murray
exaly +3 more sources
Macrophages in cholangiopathies
Current Opinion in Gastroenterology, 2021Purpose of review Cholangiopathies are a heterogeneous class of liver diseases where cholangiocytes are the main targets of liver injury. Although available and emerging therapies mainly target bile acids (ursodeoxycholic acid/UDCA, 24-Norursodeoxycholic acid/norUDCA) and related signaling pathways (obeticholic acid, fibrates ...
Alix, Bruneau +2 more
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Frontiers in Bioscience, 2008
Macrophages are ubiquitous cells physiologically involved in a variety of processes including pathogen destruction, inflammation, tissue repair and remodeling. They have a highly plastic phenotype and their functional polarization is determined by cytokines and factors found within local microenvironments.
Alessandra, Nardin +1 more
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Macrophages are ubiquitous cells physiologically involved in a variety of processes including pathogen destruction, inflammation, tissue repair and remodeling. They have a highly plastic phenotype and their functional polarization is determined by cytokines and factors found within local microenvironments.
Alessandra, Nardin +1 more
openaire +2 more sources
2011
Macrophages are a diverse phenotype of professional phagocytic cells derived from bone-marrow precursors and parent monocytes in the peripheral blood. They are essential for the maintenance and defence of host tissues, doing so by sensing and engulfing particulate matter and, when necessary, initiating a pro-inflammatory response.
Chris P, Verschoor +2 more
openaire +2 more sources
Macrophages are a diverse phenotype of professional phagocytic cells derived from bone-marrow precursors and parent monocytes in the peripheral blood. They are essential for the maintenance and defence of host tissues, doing so by sensing and engulfing particulate matter and, when necessary, initiating a pro-inflammatory response.
Chris P, Verschoor +2 more
openaire +2 more sources
Atherosclerosis and Macrophages
Acta Pathologica Japonica, 1989Atherosclerosis is undoubtedly a disease of many facets and in this review we have merely touched one angle of this issue. The best‐established cause of the disease is hyper‐cholesterolemia. Since the important role of macrophages in lipoprotein metabolism has been confirmed, current interest is focused on the role of macrophages in atherosclerosis ...
T, Watanabe +3 more
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