Inhibition of Macrophage Migration by a Skin-Reactive Polysaccharide from BCG Culture Filtrates [PDF]
, 1969 Henry P. Godfrey +2 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche +16 more
wiley +1 more source
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
Advanced Healthcare Materials, EarlyView.The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq +4 more
wiley +1 more source
Macrophage Polarization in Myocardial Ischemia‒Reperfusion Injury: Pathophysiology and Therapeutic Targets. [PDF]
Drug Des Devel TherLiu G, Dai Y, Fu C, Lv X, Qin J, Xie J.
europepmc +1 more source
Delayed Hypersensitivity in Relation to Suppression of Growth ofListeria monocytogenesby Guinea Pig Macrophages [PDF]
, 1969 Mauricio Goihman‐Yahr +2 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.Reihs et al. present the development of a humanized, animal‐free synovial membrane model for osteoarthritis. Methods include 3D biochip cultures of human‐primary OA synoviocytes with matrix and serum surrogates. Results show replication of synovial architecture and increased Yap1 expression.
Eva I. Reihs +17 more
wiley +1 more source
Multiomics integration analysis identifies tumor cell-derived MIF as a therapeutic target and potentiates anti-PD-1 therapy in osteosarcoma. [PDF]
J Immunother CancerChen W +11 more
europepmc +1 more source
Further evidence concerning macrophages producing 19 S-antibody in mice [PDF]
, 1969 H Noltenius, Michael Chahin
openalex +1 more source
Colon‐Targeted Natural Polysaccharide‐Berberine Armored Hydrogel for the Treatment of Colitis
Advanced Healthcare Materials, EarlyView.In this research, a novel hydrogel system targeting the colon is developed, incorporating Rhubarb polysaccharides and berberine‐loaded dendrimer. This hydrogel, forms through intermolecular hydrogen bonding and electrostatic interactions, accumulates in colonic tissues, effectively alleviating pathological immune hyperactivation while modulating gut ...
Miao Guo +8 more
wiley +1 more source
Titanium implant can promote M2 polarization with macrophages activation which contribute to osteogenesis and angiogenesis via inactivates JAKS signaling pathway. [PDF]
BMC ImmunolLuo X, Xiao L.
europepmc +1 more source