The transcription factor RBPJ is required for inflammatory macrophage activation in thoracic aortic dissection by mediating mechanotransduction-induced glycolysis. [PDF]
Yin ZQ +10 more
europepmc +1 more source
A synthetic 4‐arm maleimide‐terminated poly(ethylene glycol) (PEG‐4MAL) hydrogel system that combines hydrolytic ester‐linked macromer (PEG‐4eMAL) with nondegradable amide‐linked macromer (PEG‐4aMAL) in various stoichiometric ratios to tune the degradability rate. The macromers are crosslinked with dithiothreitol via thiol‐maleimide click reaction. The
Michael D. Hunckler +7 more
wiley +1 more source
Engineered immune-driven theranostics for clinical cardiology. [PDF]
Zheng JB +12 more
europepmc +1 more source
This study develops cyclic peptidepolymer conjugate nanotubes with hydrophobic, drug‐rich cores to enhance drug loading and stability, and demonstrates their responsive disassembly, pharmacokinetics, and anti‐tumour efficacy in colorectal cancer models using the anticancer drug SN‐38.
Sophie K. Hill +4 more
wiley +1 more source
Anti PD-L1 immunotherapy alters macrophage phenotypes via EGR1 and HSP90AB1 supported by integrated methodologies. [PDF]
Shou X +6 more
europepmc +1 more source
Borate‐Ion‐Stimulated Macrophages Promote Osteogenic Differentiation of Mesenchymal Stem Cells
The immune responses of mouse macrophages stimulated by borate ions promote the osteogenic differentiation and mineralization of mouse bone marrow–derived mesenchymal stem cells in an ion‐dose‐dependent manner by providing cytokines, including BMP‐2.
Kazumasa Ikedo +4 more
wiley +1 more source
The Dual Role of Macrophages in MIRI and MI by Immunity and Inflammation: Damage, Repair, Crosstalk, and Therapy. [PDF]
Miao Z +9 more
europepmc +1 more source
Beyond Bioactive Glass Composition: Using Morphology to Improve in Vitro and in Vivo Performance
Bioactive glasses can easily be shaped into granules, spheres, discs, fibers, or three‐dimensional scaffolds. The resulting morphology not only affects handling properties; it has a direct influence on various glass properties, including results of acellular immersion experiments or in vitro studies with cells or bacteria, but also on in vivo ...
Meixin Su +5 more
wiley +1 more source
Emerging macrophage-based therapies for cancer: a review of preclinical and clinical advances. [PDF]
Brancewicz J, Kucharzewska P.
europepmc +1 more source

