Results 21 to 30 of about 1,133,037 (342)

Treating Macrophages with Anti-inflammatory Nanoparticles as a Strategy to Improve Muscle Repair [PDF]

, 2019
The macrophage is an immune cell that is involved in host defense. More recent research, however, has revealed that they also play a central role in mediating the skeletal muscle regenerative process.
Yan, Derek
core   +1 more source

Cyclodextrins differentially mobilize free and esterified cholesterol from primary human foam cell macrophages

Journal of Lipid Research, 2003
Human monocyte-derived foam cell macrophages (HMFCs) are resistant to cholesterol efflux mediated by physiological acceptors. The role of the plasma membrane in regulating depletion of free cholesterol (FC) and of cholesteryl ester (CE) was investigated ...
Sue M. Liu, Anne Cogny, Maaike Kockx, Roger T. Dean, Katharina Gaus, Wendy Jessup, Leonard Kritharides   +6 more
doaj   +1 more source

Solanum nigrum induces macrophage activation through TLR4-mediated activation of JNK and macrophage autophagy through TLR4-mediated activation of p38 and JNK

Food and Agricultural Immunology, 2022
In this study, we investigated the effect of Solanum nigrum aerial parts (SNAP) on macrophage activation and macrophage autophagy in RAW264.7 cells. SNAP increased the production of immunostimulatory factors and phagocytosis in RAW264.7 cells.
Ju Hyung Yu, Min Yeong Choi, So Jung Park, Na Gyeong Geum, Jae Won Lee, Gwang Hun Park, Hyun Ji Eo, Jin Boo Jeong   +7 more
doaj   +1 more source

The significance of macrophage polarization subtypes for animal models of tissue fibrosis and human fibrotic diseases. [PDF]

, 2015
The systemic and organ-specific human fibrotic disorders collectively represent one of the most serious health problems world-wide causing a large proportion of the total world population mortality.
Ballater R, Beon M, Bryan N, Butterfield TA, Connolly MK, Desmoulière A, Fallowfield JA, Galván‐Peña S, Gordon S, Goumans M, Hu B, Ito T, Jimenez SA, Korns D, Krieg T, Lassen S, Lech M, Leibovich SJ, Lev B, Mantovani A, Mantovani A, Molumdar K, Nestle FO, O’Doherty U, Piera‐Velazquez S, Poland GA, Rafii R, Rigamonte E, Tacke F, Venbervliet B, Wang Y, Wick G, Wijesundera KK   +32 more
core   +2 more sources

Ironing Out the Details: How Iron Orchestrates Macrophage Polarization

Frontiers in Immunology, 2021
Iron fine-tunes innate immune responses, including macrophage inflammation. In this review, we summarize the current understanding about the iron in dictating macrophage polarization.
Yaoyao Xia, Yaoyao Xia, Yikun Li, Xiaoyan Wu, Qingzhuo Zhang, Siyuan Chen, Xianyong Ma, Xianyong Ma, Miao Yu, Miao Yu   +9 more
doaj   +1 more source

Macrophage autophagy in atherosclerosis [PDF]

, 2013
Macrophages play crucial roles in atherosclerotic immune responses. Recent investigation into macrophage autophagy (AP) in atherosclerosis has demonstrated a novel pathway through which these cells contribute to vascular inflammation.
Carnuccio, R., Grassia, G., Ialenti, A., Maffia, P., Maiuri, M.C., Platt, A.   +5 more
core   +2 more sources

Characterization of distinct subpopulations of hepatic macrophages in HFD/obese mice. [PDF]

, 2014
The current dogma is that obesity-associated hepatic inflammation is due to increased Kupffer cell (KC) activation. However, recruited hepatic macrophages (RHMs) were recently shown to represent a sizable liver macrophage population in the context of ...
Bandyopadhyay, Gautam, Bogner-Strauss, Juliane G, Chi, Tyler J, Chung, Heekyung, Evans, Ronald M, Franck, Niclas, Hah, Nasun, Heinrichsdorff, Jan, Mayoral, Rafael, Morinaga, Hidetaka, Oh, Da Young, Olefsky, Jerrold M, Osborn, Olivia, Pessentheiner, Ariane R, Walenta, Evelyn   +14 more
core   +2 more sources

Macrophage autophagy in macrophage polarization, chronic inflammation and organ fibrosis

Frontiers in Immunology, 2022
As the essential regulators of organ fibrosis, macrophages undergo marked phenotypic and functional changes after organ injury. These changes in macrophage phenotype and function can result in maladaptive repair, causing chronic inflammation and the ...
Jun-Hao Wen, Dong-Yi Li, Shan Liang, Chen Yang, Ji-Xin Tang, Hua-Feng Liu   +5 more
doaj   +1 more source

Antimycobacterial Effect of Selenium Nanoparticles on Mycobacterium tuberculosis

Frontiers in Microbiology, 2020
Tuberculosis (TB) remains the leading cause of death from a single infection agent worldwide. In recent years, the occurrence of TB cases caused by drug-resistant strains has spread, and is expected to continue to grow.
Hector Estevez, Ainhoa Palacios, David Gil, Juan Anguita, Juan Anguita, Maria Vallet-Regi, Maria Vallet-Regi, Blanca González, Blanca González, Rafael Prados-Rosales, Jose L. Luque-Garcia   +10 more
doaj   +1 more source

Macrophage migration inhibitory factor in acute kidneyinjury

Frontiers in Physiology, 2022
Acute kidney injury (AKI) is a complex clinical syndrome with multiple etiologies and pathogenesis, which lacks early biomarkers and targeted therapy.
Yiwei Du, Hao Hao, Heng Ma, Hongbao Liu
doaj   +1 more source