Results 21 to 30 of about 1,540,630 (392)
Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis [PDF]
, 2017 Macrophages specialize in removing lipids and debris present in the atherosclerotic plaque. However, plaque progression renders macrophages unable to degrade exogenous atherogenic material and endogenous cargo including dysfunctional proteins and ...
Ali, Sahl +19 more
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Science immunology, 2022 Description High-dimensional analysis reveals three macrophage subsets with common transcriptional and biological properties across organs. Mapping macrophage heterogeneity Tissue resident macrophages have specific roles in homeostasis, inflammation, and
Sarah A. Dick +22 more
semanticscholar +1 more source
Mesoporous Silica Nanoparticles as a Potential Platform for Vaccine Development against Tuberculosis
Pharmaceutics, 2020 The increasing emergence of new strains of Mycobacterium tuberculosis (Mtb) highly resistant to antibiotics constitute a public health issue, since tuberculosis still constitutes the primary cause of death in the world due to bacterial infection. Mtb has
Sandra Montalvo-Quirós +6 more
doaj +1 more source
Ratio of CD68/CD163 in Breast Carcinoma with and without Axillary Lymph Node Metastatic
Folia Medica Indonesiana, 2021 Tumor and its microenvironment can interact each other. Macrophage is part of tumor microenvironment. New drugs targeting specific superficial receptor of macrophage or cytokine of macrophage polarization have been found.
Priangga Adi Wiratama, Willy Sandhika
doaj +1 more source
The significance of macrophage polarization subtypes for animal models of tissue fibrosis and human fibrotic diseases. [PDF]
, 2015 The systemic and organ-specific human fibrotic disorders collectively represent one of the most serious health problems world-wide causing a large proportion of the total world population mortality.
Ballater R +32 more
core +2 more sources
The elegance of a macrophage [PDF]
Cellular & Molecular Immunology, 2017 In the latest issue of Nature Immunology, Piccolo et al.1 elegantly explored the effect of coexisting interferon-γ (IFN-γ) and interleukin 4 (IL-4) antagonistic signals on macrophage transcriptional and epigenetic profiles and, interestingly, identified a plastic cross-talk as opposed to mutually exclusive programs between M1 and M2 polarized ...
M. De Santis, M. Locati, C. Selmi
openaire +2 more sources
Food and Agricultural Immunology, 2022 In this study, we investigated the effect of Solanum nigrum aerial parts (SNAP) on macrophage activation and macrophage autophagy in RAW264.7 cells. SNAP increased the production of immunostimulatory factors and phagocytosis in RAW264.7 cells.
Ju Hyung Yu +7 more
doaj +1 more source
Macrophage autophagy in atherosclerosis [PDF]
, 2013 Macrophages play crucial roles in atherosclerotic immune responses. Recent investigation into macrophage autophagy (AP) in atherosclerosis has demonstrated a novel pathway through which these cells contribute to vascular inflammation.
Carnuccio, R. +5 more
core +2 more sources
The alveolar macrophage. [PDF]
Environmental Health Perspectives, 1971 The pulmonary macrophagic system is critical to the defense of the lung, keeping the alveoli clean and sterile and responding on demand with an adaptive outpouring of new cells into the air sacs. Under basal conditions alveolar macrophages, in common with other mononuclear phagocytes, are derived from the bone marrow.
openaire +5 more sources
Diversity, Mechanisms, and Significance of Macrophage Plasticity.
Annual Review of Pathology, 2020 Macrophages are a diverse set of cells present in all body compartments. This diversity is imprinted by their ontogenetic origin (embryonal versus adult bone marrow-derived cells); the organ context; the activation or deactivation of various signals in ...
M. Locati, G. Curtale, A. Mantovani
semanticscholar +1 more source