Results 131 to 140 of about 261,254 (319)

Multiorgan dysfunction syndrome in sepsis: Is macrophage activation syndrome secondary to infection?

open access: yesEuropean Journal of Rheumatology, 2021
Arnab Nandy   +7 more
doaj   +1 more source

Natural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome [PDF]

open access: gold, 2004
Joyce Villanueva   +6 more
openalex   +1 more source

Lipid‐Driven OLR1/FOXM1/FGF19 Axis Orchestrates Crosstalk in an Epithelial‐Fibroblast Positive Feedback Promoting Progesterone Resistance in Endometrial Cancer

open access: yesAdvanced Science, EarlyView.
It is revealed that a metabolic–stromal loop driven by oxLDL–OLR1–FOXM1–FGF19 signaling promotes progesterone resistance in endometrial cancer. OxLDL activates epithelial–fibroblast crosstalk, enhancing proliferation and hormonal insensitivity. Disruption of this circuit, especially with resveratrol, restores MPA sensitivity, highlighting a potential ...
Xingchen Li   +9 more
wiley   +1 more source

Macrophage activation syndrome: early diagnosis is key

open access: yesOpen Access Rheumatology: Research and Reviews, 2018
Butsabong Lerkvaleekul, Soamarat Vilaiyuk Division of Rheumatology, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand Abstract: Macrophage activation syndrome (MAS) is a life-threatening condition ...
Lerkvaleekul B, Vilaiyuk S
doaj  

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

open access: yesAdvanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng   +9 more
wiley   +1 more source

Uma rara causa de dispnéia com apresentação singular na tomografia computadorizada de tórax: síndrome de ativação macrofágica A very rare cause of dyspnea with a unique presentation on a computed tomography scan of the chest: macrophage activation syndrome

open access: yesJornal Brasileiro de Pneumologia, 2008
A síndrome de ativação macrofágica é uma doença rara e potencialmente fatal. Ela ocorre devido a uma alteração no sistema imunológico, com excessiva proliferação de macrófagos, geralmente causando hepatoesplenomegalia, pancitopenia e disfunção hepática ...
Rodrigo Antônio Brandão-Neto   +5 more
doaj  

Case Report: Macrophage activation syndrome due to multifocal tuberculosis in an immunocompromised patient [version 2; peer review: 2 approved]

open access: yesF1000Research
Macrophage Activation Syndrome (MAS) is a serious and life-threatening complication defined by excessive immune activation. While it’s commonly associated with rheumatic diseases, infections can also trigger MAS, with tuberculosis being a rare but ...
Amina Bouatay   +7 more
doaj   +1 more source

Spectrum of Macrophage Activation Syndrome in Rheumatic Diseases: A Kaleidoscope

open access: diamond, 2023
Rashi Maheshwari   +4 more
openalex   +1 more source

Macrophage Activation Syndrome in Pediatric Systemic Lupus Erythematosus: A Systematic Review of the Diagnostic Aspects [PDF]

open access: gold, 2021
Altynay Abdirakhmanova   +5 more
openalex   +1 more source

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