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Macrophage activation syndrome in pediatrics

Pediatric Allergy and Immunology, 2020
AbstractMacrophage activation syndrome (MAS) is a serious, potentially life‐threatening, hyperinflammatory condition, which belongs to the spectrum of hemophagocytic lymphohistiocytosis (HLH) and can complicate several immunologic and rheumatic disorders.
Alongi, Alessandra   +4 more
openaire   +3 more sources

Macrophage activation syndrome in malaria

Rheumatology International, 2009
Macrophage activation syndrome (MAS) is a clinical syndrome caused by an excessive proliferation of T lymphocytes and well-differentiated macrophages; an entity distinct from malignant histiocytosis. Although rheumatologic conditions are the common cause of MAS, a wide range of infections are also seen to cause MAS.
Rashna, Dass   +6 more
openaire   +2 more sources

Macrophage activation syndrome

Current Opinion in Rheumatology, 2002
Macrophage activation syndrome (MAS) is a serious complication of childhood systemic inflammatory disorders that is thought to be caused by excessive activation and proliferation of T lymphocytes and macrophages. Recent findings in hemophagocytic lymphohistiocytosis, a disease that is clinically similar to MAS, highlight the possible pathogenetic role ...
openaire   +3 more sources

A rare trigger for macrophage activation syndrome

Rheumatology International, 2009
Macrophage activation syndrome (MAS) is a disorder characterized by increased activation of mononuclear cells leading to phagocytosis of blood cell precursors in the bone marrow. We describe a case of MAS triggered by disseminated histoplasmosis occurring in a patient with Still's disease on long-term treatment with adalimumab.
Shikhar, Agarwal   +5 more
openaire   +2 more sources

Kawasaki disease shock syndrome and macrophage activation syndrome

Paediatrics and International Child Health, 2018
We thank Han and Lee [1] for their comments and interest in our case report [2]. They report a patient similar to ours in terms of clinical presentations but who had a final diagnosis of Kawasaki d...
Hui-Fang Yang, Hueng-Chuen Fan
openaire   +2 more sources

Rowell syndrome complicated with macrophage activation syndrome in a child

Lupus, 2019
Rowell syndrome (RS) is a rare disease characterized by the association of systemic lupus erythematosus (SLE) or cutaneous lupus with lesions similar to erythema multiforme and the presence of autoantibodies including ANA, SSA, SSB, or rheumatoid factor. Due to the low incidence of this disease, the epidemiology of RS is not clear.
I Aguirre-Martinez   +6 more
openaire   +2 more sources

[Macrophage activation syndrome].

La Revue du praticien, 2005
Macrophage activation syndrome is due to macrophage stimulation secondary to excessive cytokine secretion. Infectious (mainly viral) and neoplastic (lymphomas primarily) diseases are the mainly triggering circumstances of this syndrome associated with immunodepression.
Olivier, Fain, Jérôme, Stirnemann
openaire   +1 more source

Etanercept for therapy‐resistant macrophage activation syndrome

Pediatric Blood & Cancer, 2006
AbstractMacrophage activation syndrome (MAS) is a severe, potentially fatal complication of childhood rheumatic diseases, especially systemic onset juvenile idiopathic arthritis (SoJIA). We report a 4‐year‐old girl with probable SoJIA who presented with MAS. She did not respond to pulse methyl prednisolone and Cyclosporine A (CsA).
Yilmaz, S.   +5 more
openaire   +4 more sources

Macrophage activation syndromes.

Nouvelle revue francaise d'hematologie, 1993
The clinical and laboratory features of 47 cases of macrophage activation syndrome (MAS) were reviewed in a workshop within the Groupe Français d'Hématologie cellulaire. There was no predilection for a particular age group, while common symptoms at presentation included fever, hepatic and splenic enlargement and profound depression of blood count ...
A, Albert   +9 more
openaire   +1 more source

Macrophage activation syndrome.

The Journal of the Association of Physicians of India, 2006
Macrophage Activation Syndrome is a rare and potentially fatal disease, to be considered in patients with a SIRS like clinical presentation. Falling ESR and hyperferritinemia in the appropriate clinical setting can be the greatest clues. We report a case in which a female admitted with fever and rash, initially had systemic inflammatory response ...
M K, Kumar, M K, Suresh, D, Dalus
openaire   +1 more source

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