Results 151 to 160 of about 261,254 (319)

Fanconi Mutation in Macrophage Activation Syndrome [PDF]

Indian Journal of Pediatrics, 2021
Sidharth Yadav, Anu Maheshwari, Shreshtha Kaushik, Deonath Mahto   +3 more
openaire   +2 more sources

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

Advanced Science, EarlyView.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen, Junjun Xu, Jian Chen, Jue Hu, Xiaobo Xuan, Haifang Cai, Mingdong Yang, Zhuxian Zhou, Guowei Wang   +8 more
wiley   +1 more source

Inflammatory biomarkers in COVID-19-associated multisystem inflammatory syndrome in children, Kawasaki disease, and macrophage activation syndrome: a cohort study [PDF]

, 2021
Jackeline J Rodriguez-Smith, Emely Verweyen, Gwendolyn Clay, Ysabella Esteban, Sarah de Loizaga, Elizabeth Joy Baker, Thuy Do, Sanjeev Dhakal, Sean M. Lang, Alexei A. Grom, David D. Grier, Grant S. Schulert   +11 more
openalex   +1 more source

Magnetically‐Induced Suppression of Oxidative Stress Prevents Venous Thrombosis

Advanced Science, EarlyView.
Venous thromboembolism (VTE) remains a leading cause of cardiovascular mortality. This study demonstrates that static magnetic fields (SMF) offer a novel non‐pharmacological intervention against VTE by mitigating endothelial oxidative stress. Mechanistically, SMF elevates intracellular Ca2+, boosts ATP production, and suppresses NOX4‐mediated ROS ...
Nana Zhang, Yirong An, Shiran Tao, Shenao Qu, Minge Wu, Guantong Fang, Ziqing Chen, Weilun Song, Haoze Leng, Rongqian Wu, Yi Lyu, Xiaoli Liu, Dinghui Dong   +12 more
wiley   +1 more source

P89 | Macrophage activation syndrome secondary to salmonellosis

Italian Journal of Medicine
Premises: Macrophage activation syndrome (MAS) is a potentially life-threatening condition belonging to the histiocytoses, characterized by abnormal activation of the macrophage system and T lymphocytes, resulting in a cytokine and inflammatory storm ...
doaj   +1 more source

Macrophage activation syndrome: A cause of unresponsive malaria

Mediterranean Journal of Hematology and Infectious Diseases, 2014
Macrophage activation syndrome (MAS) results from inappropriate proliferation and activation of cells of the macrophage-histiocytic lineage. Severe infections, autoimmune diseases and malignancies are known to trigger MAS in otherwise healthy individuals.
Manish Bhagat, Sujata Kanhere, Purvi Kadakia, Varsha Phadke, Riya George, Kushagra Chaudhari   +5 more
doaj  

Inflammatory osteolysis: A conspiracy against bone [PDF]

, 2017
Abu-Amer, Abu-Amer, Anton, Bardin, Beranger, Chen, Christo, Claro, Cobelli, Coll, Dapunt, Deborah V. Novack, Dewhirst, Gabriel Mbalaviele, Georg Schett, Gravallese, Harre, Josse, Jovanovic, Kollias, Lukens, Maitra, McCall, Mukai, Negishi-Koga, Osta, Ozen, Pasco, Robaszkiewicz, Rubbert-Roth, Sanchez, Scianaro, Sharma, Steven L. Teitelbaum, Van Hauwermeiren, Wang, Zaki   +36 more
core   +2 more sources

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

Case study of tocilizumab in the treatment of macrophage activation syndrome secondary to systemic lupus erythematosus [PDF]

Zhimin Wang
openalex   +1 more source

YIM-P58. Macrophage activation syndrome: the role of infectious triggers [PDF]

, 2014
Maria Maddalena D’Errico, Federica Cuoco, Carlo M. Biancardi, Marta Torcoletti, Giovanni Filocamo, Fabrizia Corona   +5 more
openalex   +1 more source