Results 161 to 170 of about 261,254 (319)

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

Forsythoside E Alleviates Liver Injury by Targeting PKM2 Tetramerization to Promote Macrophage M2 Polarization

Advanced Science, EarlyView.
Here, the study shows for the first time that Forsythoside E (FE) can promote PKM2 tetramerization by binding to its K311 site. Furthermore, it induces metabolic reprogramming of macrophages and inhibits NLRP3 expression. Finally, it can alleviate sepsis‐induced liver injury by promoting M2 anti‐inflammatory polarization.
Bingxin Wu, Xuechun Yu, Yanling Li, Lin An, Rongrong Zhang, Rong Zhang, Fan Zhang, Zhongqiu Liu, Caiyan Wang   +8 more
wiley   +1 more source

Macrophage activation syndrome II/II

Indian Journal of Rheumatology, 2009
K Shanmuganandan, J Kotwal
doaj   +1 more source

Macrophage activation in obese type 2 diabetes: an enhanced risk for COVID-19 and Acute Respiratory Distress Syndrome? [PDF]

, 2020
Abu Saleh Md Moin, Thozhukat Sathyapalan, Ilhame Diboun, Stephen L. Atkin, Alexandra E. Butler   +4 more
openalex   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Subphenotypic Classification of Immune Response in Sepsis: Predicting Mortality and Guiding Future Personalized Immunotherapy

Acta Medica Indonesiana
The most recent definition of sepsis highlights the dysregulation of the host’s immune response to infection, which varies between individual hosts, with patients predominantly presenting with either hyperinflammation, immunoparalysis, or a combination ...
Velma Herwanto, Khie Chen Lie, Robert Sinto, Leonard Nainggolan   +3 more
doaj  

Proteinases [PDF]

, 1993
Fritz, Hans, Jochum, Marianne, Machleidt, W., Neuhof, H., Redl, H., Schlag, Günther   +5 more
core   +1 more source

Soft‐Drug‐Inspired MnSTF Nano‐Adjuvant for Safe and Synergistic cGAS–STING Activation in Tumor Immunotherapy

Advanced Science, EarlyView.
This study introduces MnSTF, a soft‐drug‐inspired nanoadjuvant that overcomes the systemic toxicity of STING agonists. Through Mn2+ coordination with an ENPP1 inhibitor, it enables safe cGAS‐STING activation, remodels the tumor immune microenvironment, and synergizes with radiotherapy or vaccines to elicit robust antitumor immunity.
Guangfei Sun, Jiancheng Pan, Rui Li, Ruoxi Li, Ziyan Liu, Jinhui Wu, Tingsheng Lin, Yiqiao Hu, Ahu Yuan   +8 more
wiley   +1 more source

Refractory Macrophage Activation Syndrome in a Patient with Systemic Lupus Erythematosus Treated with Tocilizumab

, 2015
Jin Sun Oh, Jinoh Park, Nah Kyum Lee, Seung‐Hyeon Bae, Yong‐Gil Kim, Chang‐Keun Lee, Bin Yoo   +6 more
openalex   +1 more source

Protein Tyrosine Phosphatase 1B (PTP1B) in the immune system [PDF]

, 2015
Journal not available online when checked 02/04/19.
Delibegovic, Mirela, Le Sommer, Samantha, Martin-Granados, Christina, Martina, Pesaresi   +3 more
core