“What Lies Beneath” – Macrophage Activation Syndrome Unveiled Systemic Lupus Erythematosus
JP Prathibha +2 more
openalex +1 more source
ABSTRACT RASopathies are clinically overlapping neurodevelopmental syndromes resulting from germline mutations in genes involved in the rat sarcoma/mitogen‐activated protein kinases (RAS/MAPK) pathway. Historically, RASopathies have been described by clinical phenotypes, such as Noonan syndrome and Neurofibromatosis type I.
Anastasia‐Vasiliki Madenidou +6 more
wiley +1 more source
Griscelli Syndrome Type 2 Revealed by Macrophage Activation Syndrome: Two Cases From the Same Family. [PDF]
Halimy B +4 more
europepmc +1 more source
New approaches to treating chronic obstructive pulmonary disease with Colla corii asini
Colla corii asini improves chronic obstructive pulmonary disease (COPD) treatment through anti‐inflammatory, antioxidant, immune‐modulatory, and lung‐nourishing effects, addressing current therapeutic challenges via multitarget mechanisms. Abstract Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death and disability ...
Wenchao Zhang +5 more
wiley +1 more source
Emapalumab as a Life-Saving Therapy for Macrophage Activation Syndrome in Refractory Systemic Juvenile Idiopathic Arthritis with Trisomy 21. [PDF]
Akay N +5 more
europepmc +1 more source
Optimized dengue fever animal model: IFNAR−/− BALB/c mice with intraperitoneal injection. Background screening: Between IFNAR−/− (BALB/c, C57BL/6) and AG129 mice, IFNAR−/−BALB/c exhibited the most severe symptoms: (1) highest weight loss and clinical scores; (2) peak viremia (5.44 log10 RNA copies/mL, day 4); (3) significant organ damage (liver/brain ...
Dan Liao +9 more
wiley +1 more source
Hemophagocytic Lymphohistiocytosis (HLH) or Macrophage Activation Syndrome (MAS)? A Lethal Case of Malignancy-Associated Hemophagocytic Lymphohistiocytosis in a Patient With Concurrent Autoimmune Disease. [PDF]
Cargill M +6 more
europepmc +1 more source
Multimorbidity and animal models
Multimorbidity, defined as the coexistence of ≥2 chronic conditions, is associated with aging, genetics, and environmental factors. Animal models in multimorbidity research span three tiers: simple organisms for initial screening → rodents for mechanistic analysis → large mammals for clinical prediction.
Xinpei Wang +7 more
wiley +1 more source
Macrophage activation syndrome complicating adult-onset Still's disease: the case for standardized guidelines. [PDF]
Vaseer S.
europepmc +1 more source
Macrophage Activation Syndrome after Hematopoietic Cell Transplantation [PDF]
A Sreedharan
openalex +1 more source

