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Early management of hemophagocytic lymphohistiocytosis/macrophage activation syndrome: a systematic literature review. [PDF]

EULAR Rheumatol Open
Poddighe D, Shakoory B, Geerlinks AV, Wilejto M, Kernan KF, Hines M, Romano M, Piskin D, Cinar OK, Park J, Ravelli A, Goldbach-Mansky R, de Benedetti F, Marsh RA, Canna SW, Demirkaya E.   +15 more
europepmc   +1 more source

Efficacy and safety of ruxolitinib in adult patients with refractory rheumatic disease-associated macrophage activation syndrome. [PDF]

Front Immunol
Li J, Wang R, Chen J, Xu A, Fu Y, Lin Y, Wang X, Ye S, Yuan Y, Du F, Fu Q.   +10 more
europepmc   +1 more source

Ruxolitinib targets JAK-STAT signaling to modulate neutrophil activation in refractory macrophage activation syndrome.

Blood
Ma Y, Chen X, Wang M, Meng J, Zhu D, Chen L, Xiao Y, Yi D, Shi H, Liu H, Cheng X, Su Y, Ye J, Chi H, Zhou Z, Liu T, Yang C, Teng J, Sun Y, Jia J, Hu Q.   +20 more
europepmc   +1 more source

Macrophage activation syndrome in pediatrics [PDF]

Pediatric Allergy and Immunology, 2020
AbstractMacrophage activation syndrome (MAS) is a serious, potentially life‐threatening, hyperinflammatory condition, which belongs to the spectrum of hemophagocytic lymphohistiocytosis (HLH) and can complicate several immunologic and rheumatic disorders.
Alongi, Alessandra, Naddei, Roberta, De Miglio, Laura, Natoli, Valentina, Ravelli, Angelo   +4 more
openaire   +4 more sources

Macrophage activation syndrome

Current Opinion in Rheumatology, 2002
Macrophage activation syndrome (MAS) is a serious complication of childhood systemic inflammatory disorders that is thought to be caused by excessive activation and proliferation of T lymphocytes and macrophages. Recent findings in hemophagocytic lymphohistiocytosis, a disease that is clinically similar to MAS, highlight the possible pathogenetic role ...
RAVELLI, ANGELO
core   +5 more sources

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A rare trigger for macrophage activation syndrome

Rheumatology International, 2009
Macrophage activation syndrome (MAS) is a disorder characterized by increased activation of mononuclear cells leading to phagocytosis of blood cell precursors in the bone marrow. We describe a case of MAS triggered by disseminated histoplasmosis occurring in a patient with Still's disease on long-term treatment with adalimumab.
Syed Saad Mahmood, Shikhar Agarwal, Karl S Theil   +2 more
exaly   +3 more sources