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MACROPHAGE ACTIVATION SYNDROME
Journal of Clinical Gastroenterology, 2011We recently treated a patient with adult-onset Still's disease who developed macrophage activation syndrome (MAS) secondary to disseminated histoplasmosis while being treated with adalimumab. The gastroenterology service was consulted early, before diagnosis, as the patient presented with elevated liver enzymes and disseminated intravascular ...
Bijal A, Jayakar, Philip J, Hashkes
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Macrophage Activation Syndrome
Arthritis & RheumatologyMacrophage activation syndrome (MAS) is a state of immune hyperactivation that can result in life‐threatening multisystem end‐organ dysfunction. Often termed a “cytokine storm,” MAS occurs among the rheumatic diseases most typically in Still's disease but also in systemic lupus erythematosus and Kawasaki disease.
Sean Deane, M. Eric Gershwin
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The genetics of macrophage activation syndrome
Genes & Immunity, 2020Macrophage activation syndrome (MAS), or secondary hemophagocytic lymphohistiocytosis (HLH), is a cytokine storm syndrome associated with multi-organ system dysfunction and high mortality rates. Laboratory and clinical features resemble primary HLH, which arises in infancy (1 in 50,000 live births) from homozygous mutations in various genes critical to
Grant S, Schulert, Randy Q, Cron
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Macrophage activation syndrome in malaria
Rheumatology International, 2009Macrophage activation syndrome (MAS) is a clinical syndrome caused by an excessive proliferation of T lymphocytes and well-differentiated macrophages; an entity distinct from malignant histiocytosis. Although rheumatologic conditions are the common cause of MAS, a wide range of infections are also seen to cause MAS.
Rashna, Dass +6 more
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Kawasaki disease shock syndrome and macrophage activation syndrome
Paediatrics and International Child Health, 2018We thank Han and Lee [1] for their comments and interest in our case report [2]. They report a patient similar to ours in terms of clinical presentations but who had a final diagnosis of Kawasaki d...
Hui-Fang Yang, Hueng-Chuen Fan
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[Macrophage activation syndrome].
La Revue du praticien, 2005Macrophage activation syndrome is due to macrophage stimulation secondary to excessive cytokine secretion. Infectious (mainly viral) and neoplastic (lymphomas primarily) diseases are the mainly triggering circumstances of this syndrome associated with immunodepression.
Olivier, Fain, Jérôme, Stirnemann
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Rowell syndrome complicated with macrophage activation syndrome in a child
Lupus, 2019Rowell syndrome (RS) is a rare disease characterized by the association of systemic lupus erythematosus (SLE) or cutaneous lupus with lesions similar to erythema multiforme and the presence of autoantibodies including ANA, SSA, SSB, or rheumatoid factor. Due to the low incidence of this disease, the epidemiology of RS is not clear.
I Aguirre-Martinez +6 more
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Etanercept for therapy‐resistant macrophage activation syndrome
Pediatric Blood & Cancer, 2006AbstractMacrophage activation syndrome (MAS) is a severe, potentially fatal complication of childhood rheumatic diseases, especially systemic onset juvenile idiopathic arthritis (SoJIA). We report a 4‐year‐old girl with probable SoJIA who presented with MAS. She did not respond to pulse methyl prednisolone and Cyclosporine A (CsA).
Yilmaz, S. +5 more
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Macrophage activation syndromes.
Nouvelle revue francaise d'hematologie, 1993The clinical and laboratory features of 47 cases of macrophage activation syndrome (MAS) were reviewed in a workshop within the Groupe Français d'Hématologie cellulaire. There was no predilection for a particular age group, while common symptoms at presentation included fever, hepatic and splenic enlargement and profound depression of blood count ...
A, Albert +9 more
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Macrophage activation syndrome.
The Journal of the Association of Physicians of India, 2006Macrophage Activation Syndrome is a rare and potentially fatal disease, to be considered in patients with a SIRS like clinical presentation. Falling ESR and hyperferritinemia in the appropriate clinical setting can be the greatest clues. We report a case in which a female admitted with fever and rash, initially had systemic inflammatory response ...
M K, Kumar, M K, Suresh, D, Dalus
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