Results 61 to 70 of about 551,256 (383)

Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome: Reanalysis of a Prior Phase III Trial*

open access: yesCritical Care Medicine, 2016
Objective:To determine the efficacy of anakinra (recombinant interleukin-1 receptor antagonist) in improving 28-day survival in sepsis patients with features of macrophage activation syndrome.
B. Shakoory   +7 more
semanticscholar   +1 more source

The spleen: a hub connecting nervous and immune systems in cardiovascular and metabolic diseases [PDF]

open access: yes, 2017
Metabolic disorders have been identified as major health problems affecting a large portion of the world population. In addition, obesity and insulin resistance are principal risk factors for the development of cardiovascular diseases.
Carnevale, Daniela   +3 more
core   +5 more sources

Quantum Data-Syndrome Codes [PDF]

open access: yesIEEE Journal on Selected Areas in Communications, vol. 38, no. 3, pp. 449-462, March 2020, 2019
Performing active quantum error correction to protect fragile quantum states highly depends on the correctness of error information--error syndromes. To obtain reliable error syndromes using imperfect physical circuits, we propose the idea of quantum data-syndrome (DS) codes that are capable of correcting both data qubits and syndrome bits errors.
arxiv   +1 more source

MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases. [PDF]

open access: yes, 2014
Low-grade systemic inflammation is often associated with metabolic syndrome, which plays a critical role in the development of the obesity-associated inflammatory diseases, including insulin resistance and atherosclerosis.
DeFranco, Anthony L   +19 more
core   +2 more sources

Macrophage activation syndrome

open access: yesIndian Journal of Rheumatology, 2012
Abstract Macrophage activation syndrome (MAS) is a serious, potentially life-threatening complication of rheumatic disorders, which is seen most commonly in systemic juvenile idiopathic arthritis (sJIA). It is characterised clinically by unremitting high fever, pancytopaenia, hepatosplenomegaly, hepatic dysfunction, encephalopathy, coagulation ...
Angelo Ravelli   +7 more
openaire   +2 more sources

A chemotaxis reaction-diffusion model for Multiple Sclerosis with Allee effect [PDF]

open access: yesarXiv, 2023
In this paper, we study a modification of the mathematical model describing inflammation and demyelination patterns in the brain caused by Multiple Sclerosis proposed in [Lombardo et al. (2017), Journal of Mathematical Biology, 75, 373--417]. In particular, we hypothesize a minimal amount of macrophages to be able to start and sustain the inflammatory ...
arxiv  

Vaccination with Leishmania mexicana LPG induces PD-1 in CD8+ and PD-L2 in macrophages thereby suppressing the immune response: A model to assess vaccine efficacy [PDF]

open access: yesVaccine Volume 32, Issue 11, 5 March 2014, Pages 1259-1265, 2019
Leishmania lipophosphoglycan is a molecule that has been used as a vaccine candidate, with contradictory results. Since unsuccessful protection could be related to suppressed T cell responses, we analyzed the expression of inhibitory receptor PD-1 in CD8+ and CD4+ lymphocytes and it is ligand PD-L2 in macrophages of BALB/c mice immunized with various ...
arxiv   +1 more source

Síndrome de ativação macrofágica associada com artrite idiopática juvenil sistêmica Macrophage activation syndrome associated with systemic juvenile idiopathic arthritis

open access: yesJornal de Pediatria, 2004
OBJETIVO: Descrever as características da síndrome de ativação macrofágica associada a artrite idiopática juvenil. DESCRIÇÃO DOS CASOS: Foram analisados retrospectivamente os prontuários de 462 pacientes com artrite idiopática juvenil. Destes, sete (1,5%)
Clovis Artur A. Silva   +6 more
doaj   +1 more source

Update in Hyperferritinemic Syndromes: Recognition and Management - A Scoping Review

open access: yesBrown Journal of Hospital Medicine, 2022
Elevated serum ferritin is a marker of macrophage activation and is associated with increased mortality. The hyperferritinemic syndromes which include hemophagocytic lymphohistiocytosis (HLH) and macrophage activation syndrome (MAS), catastrophic ...
Athanasios Vassilopoulos   +2 more
doaj   +1 more source

Macrophage Activation Syndrome and COVID 19: Impact of MAPK Driven Immune-Epigenetic Programming by SARS-Cov-2

open access: yesFrontiers in Immunology, 2021
The current coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has the worst affected the entire population on the earth (1, 2).
R. Roy   +5 more
semanticscholar   +1 more source

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