Results 21 to 30 of about 6,205,257 (290)

Macrophage migration inhibitory factor as an incriminating agent in vitiligo [PDF]

Anais Brasileiros de Dermatologia, 2018
: Background: Vitiligo is an autoimmune skin disorder in which the loss of melanocytes is mainly attributed to defective autoimmune mechanisms and, lately, there has been more emphasis on autoinflammatory mediators.
Azza Gaber Antar Farag, Mostafa Ahmed Hammam, Mona SalahEldeen Habib, Nada Farag Elnaidany, Mona Eaid Kamh   +4 more
doaj   +1 more source

Functional characterization of the Plasmodium falciparum and P-berghei homologues of macrophage migration inhibitory factor [PDF]

, 2007
Macrophage migration inhibitory factor (MIF) is a mammalian cytokine that participates in innate and adaptive immune responses. Homologues of mammalian MIF have been discovered in parasite species infecting mammalian hosts (nematodes and malaria ...
Sarah E. Reece, Pain, Arnab, Robert Kleemann, Kooistra, Teake, Augustijn, Kevin D., Reece, Sarah E., Thompson, Joanne, Siebum, Arjan H. G., Joanne Thompson, Kevin D. Augustijn, Waters, Andrew P., Arjan H. G. Siebum, Kleemann, Robert, Arnab Pain, Janse, Chris J., Chris J. Janse, Teake Kooistra, Carina E. Crawford, Crawford, Carina E., Andrew P Waters   +19 more
core   +1 more source

Involvement of the Macrophage Migration Inhibitory Factor (MIF) in Lipedema

Metabolites, 2023
Lipedema is a chronic disorder that mainly affects women. It is often misdiagnosed, and its etiology remains unknown. Recent research indicates an accumulation of macrophages and a shift in macrophage polarization in lipedema.
Mauro Vasella, Stefan Wolf, Eamon C. Francis, Gerrit Grieb, Pablo Pfister, Gregory Reid, Jürgen Bernhagen, Nicole Lindenblatt, Epameinondas Gousopoulos, Bong-Sung Kim   +9 more
doaj   +1 more source

Human circulating eosinophils secrete macrophage migration inhibitory factor (MIF). Potential role in asthma [PDF]

, 1998
Macrophage migration inhibitory factor (MIF) is a potent proinflammatory mediator that has been shown to potentiate lethal endotoxemia and to play a potentially important regulatory role in human acute respiratory distress syndrome (ARDS).
N Hirani, S C Donnelly, Bucala, R, Donnelly, Seamas C, A P Greening, A G Rossi, Rossi, Adriano G, Hirani, N, C Haslett, I Rahman, R Bucala, Metz, C N, C N Metz, Rahman, I, Haslett, Christopher, Greening, A. P.   +15 more
core   +1 more source

Expression of macrophage migration inhibitory factor in Aspergillus fumigatus keratitis [PDF]

International Journal of Ophthalmology, 2019
AIM: To investigate the expression of macrophage migration inhibitory factor (MIF) and detect its role in the innate immune response of fungal keratitis (FK).
Qiang Xu, Li-Ting Hu, Qian Wang, Jing Lin, Nan Jiang, Cui Li, Gui-Qiu Zhao   +6 more
doaj   +1 more source

Role for macrophage migration inhibitory factor in asthma [PDF]

Proceedings of the National Academy of Sciences, 2005
Macrophage migration inhibitory factor (MIF) is an immunologic regulator that is expressed in inflammatory and autoimmune disorders. We investigated MIF's role in asthma using genetic approaches in a mouse model and in a cohort of asthma patients.
Y, Mizue, S, Ghani, L, Leng, C, McDonald, P, Kong, J, Baugh, S J, Lane, J, Craft, J, Nishihira, S C, Donnelly, Z, Zhu, R, Bucala   +11 more
openaire   +2 more sources

Immunohistochemical detection of macrophage migration inhibitory factor in fetal and adult bovine epididymis: Release by the apocrine secretion mode? [PDF]

, 2006
Originally defined as a lymphokine inhibiting the random migration of macrophages, the macrophage migration inhibitory factor (MIF) is an important mediator of the host response to infection.
Hoffbauer, G., Jennemann, G., Gabius, Hans-Joachim, Sinowatz, Fred, Schuring, M. P., Seitz, J., Kaltner, H., Eickhoff, R.   +7 more
core   +1 more source

Receptor agonists of macrophage migration inhibitory factor [PDF]

Bioorganic & Medicinal Chemistry Letters, 2010
The cytokine MIF is involved in inflammation and cell proliferation via pathways initiated by its binding to the transmembrane receptor CD74. MIF also promotes AMPK activation with potential benefits for response to myocardial infarction and ischemia-reperfusion.
William L, Jorgensen, Sunilkumar, Gandavadi, Xin, Du, Alissa A, Hare, Alexander, Trofimov, Lin, Leng, Richard, Bucala   +6 more
openaire   +2 more sources

Efficacy of Sertraline Plus Placebo or Add-On Celecoxib in Major Depressive Disorder: Macrophage Migration Inhibitory Factor as a Promising Biomarker for Remission After Sertraline—Results From a Randomized Controlled Clinical Trial

Frontiers in Psychiatry, 2021
Introduction: Previous research delivers strong indications that inflammatory activation leads to treatment resistance in a subgroup of patients with Major Depressive Disorder (MDD). Thus, tailored interventions are needed.
Maria S. Simon, Bianka Burger, Elif Weidinger, Gara Arteaga-Henríquez, Gara Arteaga-Henríquez, Peter Zill, Richard Musil, Hemmo A. Drexhage, Norbert Müller   +8 more
doaj   +1 more source

Migration Inhibitory Factor and Macrophage Bactericidal Function [PDF]

Infection and Immunity, 1972
A homogeneous population of immunologically active lymphocytes was obtained from peritoneal exudates of guinea pigs with delayed hypersensitivity to bovine gamma globulin (BGG). The lymphocytes were cultured with and without BGG for 24 hr, and cell-free supernatant fluids were then assayed simultaneously for their ability to influence two ...
H B, Simon, J N, Sheagren
openaire   +2 more sources