Results 1 to 10 of about 44,246 (295)

MIF, MIF Alleles, and Prospects for Therapeutic Intervention in Autoimmunity [PDF]

Journal of Clinical Immunology, 2012
Macrophage migration inhibitory factor (MIF) is an innate cytokine whose main actions include counter-regulating the immunosuppressive action of glucocorticoids and inhibiting activation-induced apoptosis. MIF is encoded in a functionally polymorphic locus and human genetic studies have shown significant relationships between high-expression MIF ...
Richard Bucala
exaly   +3 more sources

Inhibition of macrophage migration inhibitory factor attenuates bleomycin-induced murine pulmonary fibrosis via the MAPK pathway [PDF]

Respiratory Research
Background Idiopathic Pulmonary Fibrosis (IPF) is a chronic progressive disease marked by excessive extracellular matrix deposition and deteriorating lung function.
Jingwei Wang, Wei Zhao, Nafeisa Dilixiati, Yuanying Wang, Yawen Song, Qiao Ye   +5 more
doaj   +2 more sources

Expression levels of MIF, NLRP1 and FOXP3 genes along with biomarker levels in patients with active form of non-segmental generalized vitiligo: A study in South Indian population [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2022
Vitiligo, the most widespread hypopigmentary syndrome, is considered to be a multifactorial disease in which the active melanocytes are lost. Vitiligo has been studied in a variety of ways, and several genes have been implicated.
Alokananda Chakraborty, Seelamneni Thulasamma, Shravan Kumar Ghali, Priyanka Pallapolu, Kuna Lahari, Towseef Amin Rafeeqi, Gulam Mohammed Husain, Farhath Jabeen, Ghazala Javed, Mohammed Abdul Waheed, Munawwar Husain Kazmi   +10 more
doaj   +1 more source

Sejarah Konversi Khalifah Al-Rasul Menjadi Khalifatullah

Jurnal El Tarikh, 2021
Abstrak Artikel ini membahas sejarah konversi khalifah al-rasul menjadi khalifatullah, yang mana, dalam perjalanan sejarah Islam pasca wafatnya rasulullah, kepemimpinan dalam Islam mengalami beberapa kali pergantian.
Mif tahul Khoiri
doaj   +1 more source

Perubahan Resapan Airtanah Pasca Gunungapi Semeru 4 Desember 2021

Jurnal Ilmu Lingkungan, 2023
Letusan gunung berapi dapat menyebabkan kerusakan ekosistem, dimana banyak vegetasi yang hilang sehingga mengurangi resapan airtanah, yang menyebabkan ketersediaan air bagi masyarakat semakin berkurang di masa yang akan datang.
Faizatul Amalia, Alfi Nur Rusydi, Ferryati Masitoh   +2 more
doaj   +1 more source

3D-QSAR study of adenosine 5’-phosphosulfate (APS) analouges as ligands for APS reductase [PDF]

Journal of the Serbian Chemical Society, 2021
Metabolism of sulfur (sulfur assimilation pathway, SAP) is one of the key pathways for the pathogenesis and survival of persistant bacteria, such as Mycobacterium tuberculosis (Mtb), in the latent period.
Erić Slavica, Cvijetić Ilija, Zloh Mire   +2 more
doaj   +1 more source

Investigation of macrophage migration inhibitory factors and gene polymorphisms in patients with psoriasis

Turkderm Turkish Archives of Dermatology and Venereology, 2021
Background and Design: Psoriasis is a multifactorial disease whose causal origin is unclear. Macrophage migration inhibitory factors (MIF) seem pivotal in inflammation and immune response in psoriasis pathogenesis.
Vildan Manav, Seval Doğruk Kaçar, Pınar Özuğuz, Saliha Handan Yıldız, Müjgan Özdemir Erdoğan, Tülay Köken   +5 more
doaj   +1 more source

Investigation of the Possible Role of Macrophage Migration Inhibitory Factor Gene -173G/C Polymorphism ın Patients with Atherosclerosis

Ahi Evran Medical Journal, 2023
Purpose: Atherosclerosis is defined as an inflammatory disease that results in the formation of atherosclerotic plaques caused by the deposition of cholesterol in the arterial intima.
Rojda TANRIVERDİ , Şenay BALCI, Merve TÜRKEGÜN ŞENGÜL, Ahmet ÇELİK, Lülüfer TAMER   +4 more
doaj   +1 more source

Role of Host and Parasite MIF Cytokines during Leishmania Infection

Tropical Medicine and Infectious Disease, 2020
Macrophage migration inhibitory factor (MIF) is an immunoregulatory cytokine that has been extensively characterized in human disease and in mouse models. Its pro-inflammatory functions in mammals includes the retention of tissue macrophages and a unique
Thomas Holowka, Richard Bucala
doaj   +1 more source

Tetralone derivatives are MIF tautomerase inhibitors and attenuate macrophage activation and amplify the hypothermic response in endotoxemic mice

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine playing crucial role in immunity. MIF exerts a unique tautomerase enzymatic activity that has relevance concerning its multiple functions and its small molecule inhibitors have ...
János Garai, Marcell Krekó, László Őrfi, Péter Balázs Jakus, Zoltán Rumbus, Patrik Kéringer, András Garami, Eszter Vámos, Dominika Kovács, Viola Bagóné Vántus, Balázs Radnai, Tamás Lóránd   +11 more
doaj   +1 more source