Results 31 to 40 of about 44,246 (295)
MIF but not MIF-2 recruits inflammatory macrophages in an experimental polymicrobial sepsis model
, 2021 Excessive inflammation drives the progression from sepsis to septic shock. Macrophage migration inhibitory factor (MIF) is of interest because MIF promoter polymorphisms predict mortality in different infections, and anti-MIF antibody improves survival ...
Bernhagen, Jürgen +12 more
core +1 more source
Brain Sciences, 2019 Neuroblastoma (NB) represents one of the most frequent pediatric solid tumors. Macrophage migration inhibitory factor (MIF) is a cytokine exerting multiple biological functions.
Eugenio Cavalli +9 more
doaj +1 more source
, 2018 A-C, WT or MIF KD 4T1 cells were grown in 10% serum-containing media overnight, and then media was replaced with fresh 10% serum or serum-free media. After 24 hours, media was sampled and tested for extracellular ATP. After 48 hours, cells were harvested
Janet V. Cross (180616) +2 more
core +1 more source
Clinical, Cosmetic and Investigational Dermatology, 2022 Danfeng Wang,1,2 Shuhui Min,1,2 Xiao Lin,1,2 Guan Jiang1,2 1Department of Dermatology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, People’s Republic of China; 2First Clinical Medical College, Xuzhou Medical University, Xuzhou, People’s ...
Wang D, Min S, Lin X, Jiang G
doaj
Macrophage Migration Inhibitory Factor in Acute Adipose Tissue Inflammation. [PDF]
PLoS ONE, 2015 Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine and has been implicated in inflammatory diseases. However, little is known about the regulation of MIF in adipose tissue and its impact on wound healing.
Bong-Sung Kim +9 more
doaj +1 more source
The MIF-CD74 Inflammatory Axis in Alphaviral Infection
, 2017 The expansion of mosquito-borne viral (arboviral) arthritis poses a significant threat to human health worldwide. Clinical reports show that arboviral arthritis can be persistent and debilitating, with evidence of bone pathology.
Mutso, Margit +7 more
core +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Biomolecules, 2019 Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine known to play a major role in inflammatory diseases such as myocardial infarction (MI), where its expression increases.
Svenja Voss +10 more
doaj +1 more source
Aging-associated Alteration in the Cardiac MIF-AMPK Cascade in Response to Ischemic Stress [PDF]
, 2008 An important role for a macrophage migration inhibitory factor (MIF)-AMP-activated protein kinase (AMPK) signaling pathway in ameliorating myocardial damage following ischemia/reperfusion has been described. An aging-associated reduction in AMPK activity
Lin Leng +7 more
core
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source