PLoS ONE, 2022 BackgroundMacrophage migration inhibitory factor (MIF) is a multifunctional cytokine that promotes neurogenesis and neuroprotection. MIF is predominantly expressed in astrocytes in the brain.
Satoshi Okazaki +10 more
doaj +1 more source
Macrophage migration inhibitory factor activates hypoxia-inducible factor in a p53-dependent manner. [PDF]
PLoS ONE, 2008 BACKGROUND: Macrophage migration inhibitory factor (MIF) is not only a cytokine which has a critical role in several inflammatory conditions but also has endocrine and enzymatic functions.
Seiko Oda +9 more
doaj +1 more source
Targeting Macrophage Migration Inhibitory Factor in Acute Pancreatitis and Pancreatic Cancer
Frontiers in Pharmacology, 2021 Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine implicated in the pathogenesis of inflammation and cancer. It is produced by various cells and circulating MIF has been identified as a biomarker for a range of diseases ...
Yongjian Wen +16 more
doaj +1 more source
Association of Macrophage Migration Inhibitory Factor Polymorphisms with Total Plasma IgE Levels in Patients with Atopic Dermatitis in Korea. [PDF]
PLoS ONE, 2016 The macrophage migration inhibitory factor (MIF) gene is located on human chromosome 22q11.2 and is linked to atopic phenotypes. Plasma MIF and log [total IgE] levels are significantly elevated in atopic dermatitis (AD) patients.
Jung Soo Kim +5 more
doaj +1 more source
Toll-Like Receptors Expression in Follicular Cells of Patients with Poor Ovarian Response [PDF]
International Journal of Fertility and Sterility, 2014 Background Poor ovarian response (POR) to gonadotropin stimulation has led to a significant decline in success rate of fertility treatment. The immune system may play an important role in pathophysiology of POR by dysfunctions of cytokines and the ...
Seyed Abdolvahab Taghavi +4 more
doaj
Expression and function of macrophage migration inhibitory factor (MIF) in melioidosis. [PDF]
PLoS Neglected Tropical Diseases, 2010 Macrophage migration inhibitory factor (MIF) has emerged as a pivotal mediator of innate immunity and has been shown to be an important effector molecule in severe sepsis.
W Joost Wiersinga +9 more
doaj +1 more source
A MIF‐Derived Cyclopeptide that Inhibits MIF Binding and Atherogenic Signaling via the Chemokine Receptor CXCR2 [PDF]
, 2020 Macrophage migration inhibitory factor (MIF) is an inflammatory cytokine and atypical chemokine with a key role in inflammatory diseases including atherosclerosis. Key atherogenic functions of MIF are mediated by noncognate interaction with the chemokine
Dewor, Manfred +27 more
core +1 more source
Genetic Variants of the MIF Gene and Susceptibility of Rectal Cancer
Pharmacogenomics and Personalized Medicine, 2021 Dongyu Chuo, Dapeng Lin, Mingdi Yin, Yuze Chen Colorectal Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Shenyang, Liaoning Province 110042, People’s Republic of ChinaCorrespondence: Yuze ...
Chuo D, Lin D, Yin M, Chen Y
doaj
AHNAK and inflammatory markers predict poor survival in laryngeal carcinoma. [PDF]
, 2012 AHNAK/Desmoyokin is a giant protein which has been recently linked to reorganization of the actin cytoskeleton, cellular migration and invasion. Here, we investigated the role of AHNAK in the pathophysiology of larynx carcinoma-one of the major subtypes ...
Reinhard Zeidler +13 more
core +2 more sources
Cell Death and Disease, 2021 Macrophage migration inhibitory factor (MIF) is an upstream regulator of innate immunity, but its expression is increased in some cancers via stabilization with HSP90-associated chaperones.
Luisa Klemke +7 more
doaj +1 more source