Results 11 to 20 of about 44,246 (295)

Expression and Correlation of MIF and ERK1/2 in Liver Cirrhosis and Hepatocellular Carcinoma Induced by Hepatitis B

Pharmacogenomics and Personalized Medicine, 2023
Dong Jia,* Bin Li,* Jun-Ke Wang,* Pan Wang, Chu-Yi Li, Li-Xia Lu, Wen-Yan Tian, Xiao-Hui Yu, Jiu-Cong Zhang, Ying Zheng Department of Gastroenterology, The 940th Hospital of Joint Service Logistics Support Force of Chinese People’s Liberation
Jia D, Li B, Wang JK, Wang P, Li CY, Lu LX, Tian WY, Yu XH, Zhang JC, Zheng Y   +9 more
doaj   +1 more source

Differential regulation of macrophage activation by the MIF cytokine superfamily members MIF and MIF‐2 in adipose tissue during endotoxemia [PDF]

The FASEB Journal, 2020
Abstract Sepsis is a leading cause of death worldwide and recent studies have shown white adipose tissue (WAT) to be an important regulator in septic conditions. In the present study, the role of the inflammatory cytokine macrophage migration inhibitory factor (MIF) and its structural homolog D
Kim, Bong-Sung, Tilstam, Pathricia V, Arnke, Kevin, Leng, Lin, Ruhl, Tim, Piecychna, Marta, Schulte, Wibke, Sauler, Maor, Frueh, Florian S, Storti, Gabriele, Lindenblatt, Nicole, Giovanoli, Pietro, Pallua, Norbert, Bernhagen, Jürgen, Bucala, Richard   +14 more
openaire   +9 more sources

Macrophage Migration Inhibitory Factor Promotes Expression of Matrix Metalloproteinases 1 and 3 in Spinal Cord Astrocytes following Gecko Tail Amputation

Journal of Integrative Neuroscience, 2023
Background: The matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that play a variety of physiological and pathological roles in development, remodeling of tissues and diseases, mainly through degradation of various components of the ...
Haijun Zhang, Chunshuai Sun, Bingqiang He, Xingyuan Zhang, Huifei Hao, Yuxuan Hou, Aicheng Li, Yongjun Wang, Yingjie Wang   +8 more
doaj   +1 more source

Autophagy Inhibition Induces the Secretion of Macrophage Migration Inhibitory Factor (MIF) with Autocrine and Paracrine Effects on the Promotion of Malignancy in Breast Cancer

Biology, 2020
Breast cancer is the main cause of cancer-related death in women in the world. Because autophagy is a known survival pathway for cancer cells, its inhibition is currently being explored in clinical trials for treating several types of malignancies.
Israel Cotzomi-Ortega, Arely Rosas-Cruz, Dalia Ramírez-Ramírez, Julio Reyes-Leyva, Miriam Rodriguez-Sosa, Patricia Aguilar-Alonso, Paola Maycotte   +6 more
doaj   +1 more source

Human circulating eosinophils secrete macrophage migration inhibitory factor (MIF). Potential role in asthma [PDF]

, 1998
Macrophage migration inhibitory factor (MIF) is a potent proinflammatory mediator that has been shown to potentiate lethal endotoxemia and to play a potentially important regulatory role in human acute respiratory distress syndrome (ARDS).
N Hirani, S C Donnelly, Bucala, R, Donnelly, Seamas C, A P Greening, A G Rossi, Rossi, Adriano G, Hirani, N, C Haslett, I Rahman, R Bucala, Metz, C N, C N Metz, Rahman, I, Haslett, Christopher, Greening, A. P.   +15 more
core   +1 more source

The Role of Macrophage Migration Inhibitory Factor (MIF) and D-Dopachrome Tautomerase (D-DT/MIF-2) in Infections: A Clinical Perspective

Biomedicines, 2023
Macrophage migration inhibitory factor (MIF) and its homolog, D-dopachrome tautomerase (D-DT), are cytokines that play critical roles in the immune response to various infectious diseases.
David Breidung, Ioannis-Fivos Megas, David Lysander Freytag, Jürgen Bernhagen, Gerrit Grieb   +4 more
doaj   +1 more source

Functional characterization of the Plasmodium falciparum and P-berghei homologues of macrophage migration inhibitory factor [PDF]

, 2007
Macrophage migration inhibitory factor (MIF) is a mammalian cytokine that participates in innate and adaptive immune responses. Homologues of mammalian MIF have been discovered in parasite species infecting mammalian hosts (nematodes and malaria ...
Sarah E. Reece, Pain, Arnab, Robert Kleemann, Kooistra, Teake, Augustijn, Kevin D., Reece, Sarah E., Thompson, Joanne, Siebum, Arjan H. G., Joanne Thompson, Kevin D. Augustijn, Waters, Andrew P., Arjan H. G. Siebum, Kleemann, Robert, Arnab Pain, Janse, Chris J., Chris J. Janse, Teake Kooistra, Carina E. Crawford, Crawford, Carina E., Andrew P Waters   +19 more
core   +1 more source

Immunohistochemical detection of macrophage migration inhibitory factor in fetal and adult bovine epididymis: Release by the apocrine secretion mode? [PDF]

, 2006
Originally defined as a lymphokine inhibiting the random migration of macrophages, the macrophage migration inhibitory factor (MIF) is an important mediator of the host response to infection.
Hoffbauer, G., Jennemann, G., Gabius, Hans-Joachim, Sinowatz, Fred, Schuring, M. P., Seitz, J., Kaltner, H., Eickhoff, R.   +7 more
core   +1 more source

Human embryonic stem cells secrete macrophage migration inhibitory factor: A novel finding

PLoS ONE, 2023
Macrophage migration inhibitory factor (MIF) is expressed in a variety of cells and participates in important biological mechanisms. However, few studies have reported whether MIF is expressed in human Embryonic stem cells (ESCs) and its effect on human ...
Yanzhao Wei, Xiaohan Zheng, Ting Huang, Yuanji Zhong, Shengtong Sun, Xufang Wei, Qibing Liu, Tan Wang, Zhenqiang Zhao   +8 more
doaj   +2 more sources

The role of macrophage migration inhibitory factor in promoting benign prostatic hyperplasia epithelial cell growth by modulating COX-2 and P53 signaling

Biology Open, 2020
Inflammation and proinflammatory cytokines have been implicated in the progression of benign prostatic hyperplasia (BPH). Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine. Our previous study found that MIF is highly expressed in
Hualin Song, Qi Shen, Shuai Hu, Jie Jin
doaj   +1 more source