Results 101 to 110 of about 1,228,727 (302)
Lipin-1 contributes to IL-4 mediated macrophage polarization [PDF]
, 2020 Macrophage responses contribute to a diverse array of pathologies ranging from infectious disease to sterile inflammation. Polarization of macrophages determines their cellular function within biological processes.
Blackburn, Cassidy M R +7 more
core +1 more source
Macrophage polarization in kidney diseases [PDF]
Macrophage, 2015 Macrophage accumulation associates closely with the degree of renal structural injury and renal dysfunction in human kidney diseases. Depletion of macrophages reduces while adoptive transfer of macrophages worsens inflammation in animal models of the renal injury.
Shi-You Chen, Shaojiang Tian
openaire +3 more sources
Cell Death Discovery, 2022 Crush syndrome (CS) is a life-threatening illness in traffic accidents and earthquakes. Crush syndrome-induced acute kidney injury (CS-AKI) is considered to be mainly due to myoglobin (Mb) circulation and deposition after skeletal muscle ruptures and ...
Ning Li +11 more
semanticscholar +1 more source
Autophagic reprogramming of bone marrow–derived macrophages [PDF]
, 2023 Macro-autophagy is a highly conserved catabolic process among eukaryotes affecting macrophages. This work studies the genetic regulatory network involving the interplay between autophagy and macrophage polarization (activation).
Abdellatif, Ahmed +3 more
core +1 more source
Journal of Experimental & Clinical Cancer Research, 2021 Background Hepatocellular carcinoma (HCC) cells-secreted exosomes (exo) could stimulate M2 macrophage polarization and promote HCC progression, but the related mechanism of long non-coding RNA distal-less homeobox 6 antisense 1 (DLX6-AS1) with HCC-exo ...
Lin-pei Wang +6 more
doaj +1 more source
Epigenetic control of macrophage polarization [PDF]
European Journal of Immunology, 2011 AbstractEpigenetic control of gene expression is critical for cellular differentiation and development. Macrophage development, polarization and activation are also controlled by DNA and histone modifications. This Viewpoint summarizes the recent findings on the role of histone modifications regulating macrophage polarization toward M1 and M2 subtypes.
Shizuo Akira, Osamu Takeuch
openaire +3 more sources
Regulatory Effects of Quercetin on M1/M2 Macrophage Polarization and Oxidative/Antioxidative Balance
Nutrients, 2021 Macrophage polarization plays essential and diverse roles in most diseases, such as atherosclerosis, adipose tissue inflammation, and insulin resistance.
Cheng‐Fang Tsai +7 more
semanticscholar +1 more source
Alternatively activated macrophages promote pancreatic fibrosis in chronic pancreatitis. [PDF]
, 2015 Chronic pancreatitis (CP) is a progressive and irreversible inflammatory and fibrotic disease with no cure. Unlike acute pancreatitis (AP), we find that alternatively activated macrophages (AAMs) are dominant in mouse and human CP.
Chawla, Ajay +6 more
core +2 more sources
The Prognostic Role of Macrophage Polarization in the Colorectal Cancer Microenvironment [PDF]
, 2021 Macrophages are among the most common cells in the colorectal cancer microenvironment, but their prognostic significance is incompletely understood.
Akimoto, Naohiko +28 more
core +1 more source
Macrophage polarization and allergic asthma [PDF]
Translational Research, 2018 Allergic asthma is associated with airway inflammation and airway hyperresponsiveness. Macrophage polarization has been shown to have a profound impact on asthma pathogenesis. On exposure to local microenvironments, recruited macrophages can be polarized into either classically activated (or M1) or alternatively activated (or M2) phenotypes. Macrophage
Arjun Saradna +4 more
openaire +3 more sources