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Macrophage polarity in cancer: A review
Journal of Cellular Biochemistry, 2018AbstractMacrophages are the most abundant cells within the tumor stroma displaying noticeable plasticity, which allows them to perform several functions within the tumor microenvironment. Tumor‐associated macrophages commonly refer to an alternative M2 phenotype, exhibiting anti‐inflammatory and pro‐tumoral effects.
Masoud Najafi +11 more
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Macrophage polarization in placenta accreta and macrophage‐trophoblast interactions
American Journal of Reproductive Immunology, 2022AbstractProblemPlacenta accreta (PA) is defined by an abnormal invasion of placental trophoblasts into the myometrium, which can lead to serious postpartum complications. Macrophages play an important role in the regulation of trophoblast function.
Jia‐hui Che +3 more
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European Journal of Pharmacology, 2020
Macrophages can be affected by a variety of factors to change their phenotype and thus affect their function. Activated macrophages are usually divided into two categories, M1-like macrophages and M2-like macrophages. Both M1 macrophages and M2 macrophages are closely related to inflammatory responses, among which M1 macrophages are mainly involved in ...
Chen, Yunna +3 more
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Macrophages can be affected by a variety of factors to change their phenotype and thus affect their function. Activated macrophages are usually divided into two categories, M1-like macrophages and M2-like macrophages. Both M1 macrophages and M2 macrophages are closely related to inflammatory responses, among which M1 macrophages are mainly involved in ...
Chen, Yunna +3 more
exaly +3 more sources
Trends in Immunology, 2002
Mononuclear phagocytes are versatile cells that can express different functional programs in response to microenvironmental signals. Fully polarized M1 and M2 (or alternatively activated) macrophages are the extremes of a continuum of functional states.
Alberto Mantovani +2 more
exaly +6 more sources
Mononuclear phagocytes are versatile cells that can express different functional programs in response to microenvironmental signals. Fully polarized M1 and M2 (or alternatively activated) macrophages are the extremes of a continuum of functional states.
Alberto Mantovani +2 more
exaly +6 more sources
Macrophage polarization in tumour progression
Seminars in Cancer Biology, 2008Macrophages are a fundamental part of the innate defense mechanisms, which can promote specific immunity by inducing T cell recruitment and activation. Despite this, their presence within the tumour microenvironment has been associated with enhanced tumour progression and shown to promote cancer cell growth and spread, angiogenesis and ...
SICA, Antonio +9 more
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Modulating macrophage polarization by photobiomodulation
Lasers in Medical SciencePhotobiomodulation (PBM), employing low-power lasers and light-emitting diodes (LEDs), has emerged as an innovative therapeutic modality for modulating macrophage polarization. In this review, we summarized the involvement of PBM in macrophage polarization and described the light physical parameters involved with polarization, focusing on its ability ...
Victoria Batista, Ferreira +2 more
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Macrophage polarization in adenomyosis: A review
American Journal of Reproductive ImmunologyAbstractAdenomyosis (AM) is a common gynecological disorder characterized by the presence of endometrial glands and stroma within the uterine myometrium. It is associated with abnormal uterine bleeding (AUB), dysmenorrhea, and infertility. Although several mechanisms have been proposed to elucidate AM, the exact cause and development of the condition ...
Yingying Qiu +5 more
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Macrophage Polarization and Osteoclast Differentiation
Macrophages are a key player to regulate rheumatoid arthritis pathogenesis from onset to remission. They can alter innate functions under microenvironmental conditions. To understand heterogeneous functions of macrophages in rheumatoid arthritis, several activated statuses of macrophages should be mimicked in vitro.Noritaka, Saeki, Akihiro, Nakata
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