Results 331 to 336 of about 166,541 (336)

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

Trends in Immunology, 2002
Mononuclear phagocytes are versatile cells that can express different functional programs in response to microenvironmental signals. Fully polarized M1 and M2 (or alternatively activated) macrophages are the extremes of a continuum of functional states.
MANTOVANI A, SOZZANI, Silvano, LOCATI M, ALLAVENA P, SICA A.   +4 more
openaire   +4 more sources

Organelle Specific Macrophage Engineered Vesicles Differentially Reprogram Macrophage Polarization

Advanced Healthcare Materials
AbstractTumor‐associated macrophages (TAMs) represent the majority of the immune cells present in the tumor microenvironment. These macrophages exhibit an anti‐inflammatory (M2)‐like physiological state and execute immune‐suppressive and tumor‐supporting properties. With TAMs being plastic, there is a growing interest in reprogramming them toward a pro‐
Khaga R. Neupane, Surya P. Aryal, Brock T. Harvey, Geraldine San Ramon, Byeong Chun, J. Robert McCorkle, Jill M. Kolesar, Peter M. Kekenes‐Huskey, Christopher I. Richards   +8 more
openaire   +2 more sources

Macrophage Polarization and Osteoclast Differentiation

Macrophages are a key player to regulate rheumatoid arthritis pathogenesis from onset to remission. They can alter innate functions under microenvironmental conditions. To understand heterogeneous functions of macrophages in rheumatoid arthritis, several activated statuses of macrophages should be mimicked in vitro.
Noritaka, Saeki, Akihiro, Nakata
openaire   +2 more sources

P311 Influences Macrophage Polarization

Physiology
Obesity is a pandemic disease that has become a serious concern worldwide. In United States, recently self-reported obesity rates of adults were escalated to 40%. In the early phase of obesity, excessive macrophage infiltration and disequilibrium of macrophage phenotypes (M1 vs. M2 or vice versa) play a critical role in the microenvironment of adipose
Sreenu Boddupally, Pavana Jyotsna Kasaram, Kameswara Badri   +2 more
openaire   +1 more source

Macrophage Plasticity and Polarization

2015
Maria Rosaria Galdiero, Alberto Mantovani   +1 more
openaire   +1 more source

Macrophage Activation and Polarization

2016
openaire   +1 more source