Results 231 to 240 of about 2,020,072 (390)

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

Macrophages expressing chimeric cytokine receptors have an inflammatory phenotype and antitumoral activity upon IL-10 or TGFβ stimulation. [PDF]

J Immunother Cancer
Traxel S, Schmidt F, Beerli C, Vuong DV, Speck RF, Bredl S.   +5 more
europepmc   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Cytochrome b5 reductase orchestrates IL-1β production in macrophages through FAD. [PDF]

Cell Death Dis
Fu J, Liu Z, Zhang H, Zhang X, Liu S, Mei X, Zeng X, Ren W.   +7 more
europepmc   +1 more source

Mediation of Delayed Hypersensitivity by Peripheral Blood Lymphocytes in Vitro and by Their Products in Vivo and in Vitro, Morphology of in Vitro Lymphocyte-Macrophage Interaction [PDF]

, 1968
Harry Bartfeld, Robert L. Kelly
openalex   +1 more source

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

Advanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram, Majd Machour, Janette Zavin, Roy Meretzki, Reut Lev‐Ari, Shulamit Levenberg   +5 more
wiley   +1 more source

Immunological characteristics and functions of macrophages in Mycobacterium leprae infection. [PDF]

BMC Immunol
Zhang X, Jiang H, Liu W, Wang H.
europepmc   +1 more source

Inhibition of Macrophage Migration by a Skin-Reactive Polysaccharide from BCG Culture Filtrates [PDF]

, 1969
Henry P. Godfrey, Harold Baer, S D Chaparas   +2 more
openalex   +1 more source

Mechanically Tunable Bone Scaffolds: In Vivo Hardening of 3D‐Printed Calcium Phosphate/Polycaprolactone Inks

Advanced Functional Materials, EarlyView.
A 3D bone scaffold with osteogenic properties and capable of hardening in vivo is developed. The scaffold is implanted in a ductile state, and a phase transformation of the ceramic induces the stiffening and strengthening of the scaffold in vivo. Abstract Calcium phosphate 3D printing has revolutionized customized bone grafting.
Miguel Mateu‐Sanz, Pablo Varela, Laura del‐Mazo‐Barbara, Irene Lodoso‐Torrecilla, Emilio Jiménez‐Piqué, Jordi Franch, Miguel Alaminos, Maria‐Pau Ginebra   +7 more
wiley   +1 more source

AXL activation governs the liver microenvironment to protect ischemia-reperfusion injury by suppressing NLRP3 inflammasome. [PDF]

Cell Mol Biol Lett
Liu D, Zhan M, Yao L, Liu X, Zhang R, Zha L, Zhang X, Xu Y, Fang Q, Cai H, Yan Q, Wang W, Du J, Chen L.   +13 more
europepmc   +1 more source