Results 261 to 270 of about 1,598,228 (339)

Extracellular vesicle-derived miRNA-182-5p educates macrophages towards an immunosuppressive phenotype in pancreatic cancer. [PDF]

Signal Transduct Target Ther
Singh B, Gaur P, Bose P, Zhang Y, Li Y, Zhang Z, Kandhavelu J, Klotzbier W, Jayatilake M, Bansal S, Farhan M, Deol S, Banerjee PP, Unger K, Gupta S, Verma V, Cheema AK.   +16 more
europepmc   +1 more source

Precise Control of Drug Release in Machine Learning‐Designed Antibody‐Eluting Implants for Postoperative Scarring Inhibition in Glaucoma

Advanced Healthcare Materials, EarlyView.
We developed a micro‐sized, biocompatible implant for postoperative sustained delivery of anti‐fibrotic antibodies in glaucoma surgery. Machine learning‐guided optimization of polymer composition, implant geometry, and porosity enabled precise control of drug release.
Mengqi Qin, Wenbing Jiang, Kai Xin Thong, Zeynep Ulker, Brihitejas Patel, Cynthia Yu‐Wai‐Man   +5 more
wiley   +1 more source

Tumor derived adiponectin induces immunosuppressive macrophages in upper tract urothelial carcinoma. [PDF]

Transl Oncol
Shen CH, Chen P, Chang CB, Chang CC, Wang M, Chou LP, Lai YY, Lee MY, Wu SF.   +8 more
europepmc   +1 more source

Reviewer #1 (Public review): S100a4+ alveolar macrophages accelerate the progression of precancerous atypical adenomatous hyperplasia by promoting fatty acid metabolism [PDF]

Hong Huang, Ying Yang, Qiuju Zhang, Yongfeng Yang, Zhenqi Xiong, Shengqiang Mao, Tingting Song, Yilong Wang, Zhiqiang Liu, Hong Bu, Li Zhang, Le Zhang   +11 more
openalex   +1 more source

A Microphysiological Interface of Skeletal Myobundles and Inflamed Adipose Tissue for Recapitulating Muscle Dysfunction in an Obese Microenvironment

Advanced Healthcare Materials, EarlyView.
A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim, Tianxin Cao, Zhengpeng Wan, Jaesang Kim, Zhuxuan Li, Legairre A. Radden II, Rakesh Santhanam, Eunkyung Clare Ko, Tatsuya Osaki, Sarah Spitz, Hyunmin Moon, Maria Proestaki, Seokbeom Roh, Gyudo Lee, Jessie S. Jeon, Curtis R. Warren, Roger D. Kamm   +16 more
wiley   +1 more source

Extracellular CIRP augments inflammation in acute kidney injury via NKG2D-positive macrophages. [PDF]

Front Immunol
Zhang F, Jin H, Tan C, Wang P, Brenner M.   +4 more
europepmc   +1 more source

Production of granulocyte-macrophage colony-stimulating factor by cultured human tracheal epithelial cells.

, 1992
Laurie Churchill, B Friedman, Schleimer Rp, David Proud   +3 more
openalex   +1 more source

P0130 Assessment of macrophage types in the intestinal tissue of treatment naïve Inflammatory Bowel Disease patients in relation to their disease and activation of the CCL2/CCR2 pathway [PDF]

Jasmina Begüm, Arooj Fatima, Peter J. Rimmer, Tariq Iqbal, Victor Stoica, Maame Amma Owusu, Iva Lelios, HM McGettrick, Richard W.D. Welford, A Iqbal   +9 more
openalex   +1 more source

Bioengineered Pancreatic Cancer Immunosuppressive Microenvironment Models for Screening Immunotherapies

Advanced Healthcare Materials, EarlyView.
Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro, Margarida Henriques‐Pereira, Bruno M. Neves, Vítor M. Gaspar, João F. Mano   +4 more
wiley   +1 more source

Hepatic Macrophages in Chronic Hepatitis B: Balancing Immunity and Pathology. [PDF]

Biology (Basel)
Pathania AS, Bhat SA, Adepoju LA, Kharbanda KK, Osna NA.   +4 more
europepmc   +1 more source