Results 31 to 40 of about 3,551 (173)

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola, Marica Rubino, Antonella Riva, Pasquale Striano   +3 more
wiley   +1 more source

Microvascular and Morphologic Changes of the Macula over Lifetime

Life, 2022
In ocular, neurologic, and cardiovascular diseases, macular segmentation data from spectral-domain optical coherence tomography (SD-OCT) provide morphologic, and OCT-angiography (OCTA) results give microvascular information about the macula.
Mael Lever, Ying Chen, Moritz Glaser, Jan Darius Unterlauft, Claudia Lommatzsch, Nikolaos E. Bechrakis, Michael R. R. Böhm   +6 more
doaj   +1 more source

Outcomes of Recurrent Laryngeal Nerve Reinnervation for Pediatric Unilateral Vocal Fold Paralysis

The Laryngoscope, EarlyView.
The objective of this study was to describe voice outcomes from the largest single‐center, single‐surgeon experience with recurrent laryngeal nerve reinnervation for pediatric unilateral vocal fold paralysis. In 102 patients who underwent reinnervation, we demonstrate that reinnervation is an effective and durable intervention for treatment of ...
Theodore A. Gobillot, Linda M. Carroll, Karen B. Zur   +2 more
wiley   +1 more source

Slow‐Phase Nystagmus Velocity as a Risk Factor for Lateral Canal BPPV Recurrence

The Laryngoscope, EarlyView.
This study investigated slow‐phase nystagmus velocity (SPV) at initial diagnosis as an objective vestibular predictor for the recurrence of lateral semicircular canal benign paroxysmal positional vertigo (BPPV). Binomial logistic regression analysis demonstrated that an elevated initial SPV is a novel, independent risk factor for recurrence ...
Chung Yoh Kim, Woo Jin Kim
wiley   +1 more source

Functional Dissociation Between Cervical VEMP and Posterior Canal vHIT in 1770 Unselected Ears

The Laryngoscope, EarlyView.
Cervical VEMP and posterior canal vHIT are conventionally treated as measures of a single inferior vestibular unit. In 1770 unselected ears from a diagnosis‐agnostic registry, the two tests disagreed in 72.7% of ears abnormal on at least one test, with chance‐corrected agreement near zero (κ = 0.097) and unchanged across age strata.
Fumiyuki Goto, Yukiko Tsuda, Koichiro Wasano   +2 more
wiley   +1 more source

Congenital toxoplasmosis as one phenocopy of North Carolina Macular Dystrophy (NCMD/MCDR1)

American Journal of Ophthalmology Case Reports, 2019
Purpose: To highlight the striking similarities between the lesions of congenital toxoplasmosis (CT) and North Carolina Macular Dystrophy (NCMD) using multimodal imaging including spectral domain optical coherence tomography (SD-OCT).
Kent W. Small, MD, Andrea L. Vincent, MBChB, MD, Chelsey L. Knapper, DO, Fadi S. Shaya, BS   +3 more
doaj   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

Neuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji, Yuan Zhang, Jinyi Zhao, Yiping Lu, Chengkun Wang   +4 more
wiley   +1 more source

OCTA: Essential or Gimmick?

Ophthalmology and Therapy
This commentary article delves into the transformative role of optical coherence tomography angiography (OCTA) in diagnosing and managing a wide array of eye conditions, including diabetic retinopathy, age-related macular degeneration, retinal vein ...
Siddharth Gandhi, Niveditha Pattathil, Netan Choudhry   +2 more
doaj   +1 more source

Digital holographic microscopy: use of artificial intelligence to enable rapid blood culture Gram stain digitization and interpretation

Journal of Clinical Microbiology
Gram staining is one of the most commonly performed tests in the clinical microbiology laboratory. Results are used to both guide empiric antimicrobial therapy as well as downstream laboratory procedures, including culture workup.
Kenneth P. Smith, Erin Boulanger, Michael Elkan, Jeffrey Fink, Sofia Cagina, Alena Shamsheyeva, Kyle Spafford, Richard Stahl, Oleg Gusyatin   +8 more
doaj   +1 more source

Asphalt Concrete Overlay Optimization Based on Pavement Performance Models

Advances in Materials Science and Engineering, 2017
The life cycle length of pavement with asphalt concrete material (ACM) surfacing is significantly influenced, in addition to transport loading and climatic conditions, by design method and rehabilitation timing.
Jan Mikolaj, Lubos Remek, Marian Macula
doaj   +1 more source