Results 51 to 60 of about 3,551 (173)

Gastritis and age‐related macular degeneration: Potential roles of metabolomic dysregulation and photoreceptor alterations

VIEW, EarlyView.
Abstract Age‐related macular degeneration (AMD) is a degenerative retinal disorder and a leading cause of global visual impairment, yet effective treatments remain limited. While gastritis is a prevalent clinical condition among older populations and has been associated with adverse effects on the central nervous system, its potential association with ...
Jingxin Zhou, Jiawei Wang, Yingcheng He, Jing Cao, Jiayu Duan, Juan Ye   +5 more
wiley   +1 more source

Stem Cell Ophthalmology Treatment Study (SCOTS): Bone Marrow-Derived Stem Cells in the Treatment of Age-Related Macular Degeneration

Medicines, 2020
Background: Dry age-related macular degeneration (AMD) is one of the leading causes of vision loss in older patients. The macula accumulates drusen with loss of retinal pigment epithelial cells and photoreceptors.
Jeffrey N. Weiss, Steven Levy
doaj   +1 more source

Unveiling Otolith Mystery: Contemporary Testing Approaches and Their Clinical Significance

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Otolith is a critical component of the peripheral vestibular system responsible for detecting linear acceleration. Dysfunction of the otolith organs can lead to vertigo, balance disturbances, and gaze instability. By elucidating the physiological foundations and evaluating both current and emerging methods for assessing otolith ...
Shun Zhou, E Tian, Hua‐Jing Yang, Jun Wang, Zhao‐Qi Guo, Jing‐Yu Chen, Wan‐Di Xu, Jia‐Qi Guo, Zhang‐Hong Zhou, Shi‐Yu Shi, Xi‐Xi Yu, Xin‐Bo Gao, Ni Zhai, Xin Ma, Qing Zhang, Yi‐Sheng Lu, Su‐Lin Zhang   +16 more
wiley   +1 more source

Vortex Veins in the Macula [PDF]

Ophthalmologica, 2010
A 54-year-old man with diabetes mellitus had abnormal choroidal vessels in the right eye. Whirled tributaries, the choroidal part of the vortex vein, and the scleral canal beneath the central foveal area were visible. This is a rare case of vortex veins in the macula.
M, Sekimoto, S, Hayasaka, M, Watanabe, T, Setogawa   +3 more
openaire   +2 more sources

The ‘Great Frost’ of 1708–9 in Britain and the Condescensions of Posterity

History, EarlyView.
Abstract This article explores the ‘great frost’ of 1709 and its impact on economic life in Britain, challenging a popular view that, based on gross domestic product (GDP) estimates, it was catastrophic. It shows that the annual GDP figures for the period have such wide error margins that they cannot establish the scale of the disruption; that the ...
Julian Hoppit
wiley   +1 more source

MAFF Expression Reshapes Key Stress-Response Proteins During Light-Induced Injury

Antioxidants
MAFF is a small MAF family transcription factor involved in antioxidant signaling and cytoprotective gene regulation. MAFF is differentially expressed across retinal regions, with particularly low expression in macular Müller cells, which play a central ...
Jialing Zhang, Ting Zhang, Azhar Dzulhadj B. Arafah, Sora Lee, Michelle Yam, Jingwen Zeng, Chen-Chin Chang, Xiaosuo Wang, Mark C. Gillies, Ling Zhu   +9 more
doaj   +1 more source

Book Value Risk Management of Banks: Limited Hedging, HTM Accounting, and Rising Interest Rates

Journal of Accounting Research, EarlyView.
ABSTRACT We document that as interest rates rose in 2022, banks largely left long‐duration assets exposed to interest rate risk while shielding the accounting value of their balance sheets. Call report and Securities and Exchange Commission (SEC) data show that only about 6% of U.S.
João Granja, Erica Xuewei Jiang, Gregor Matvos, Tomasz Piskorski, Amit Seru   +4 more
wiley   +1 more source

The Functional Role and Molecular Characterization of the Therapeutic Target CLDN6 in Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick, Margaretha A. Skowron, Gereon Poschmann, Patrick Petzsch, Ann Kathrin Bergmann, Kai Stühler, Jochen Hecht, Daniel Nettersheim   +7 more
wiley   +1 more source

Expanding Genetic and Clinical Spectra of Inherited Retinal Dystrophies: Identification of Three Novel PRPH2 Variants

Biomedicines
Background/Objectives: Pathogenic variants in the PRPH2 gene are implicated in a wide spectrum of Inherited Retinal Dystrophies (IRDs), which show significant phenotypic heterogeneity.
Raffaella Cascella, Jacopo Sebastiani, Claudia Strafella, Giulia Calvino, Sarah Andreucci, Michele D’ambrosio, Stefania Zampatti, Jung Hee Levialdi Ghiron, Benedetto Falsini, Andrea Cusumano, Emiliano Giardina   +10 more
doaj   +1 more source

Interpreting the structure–function relationship in high myopia‐associated glaucoma: A review

Acta Ophthalmologica, EarlyView.
Abstract Visual field (VF) interpretation in high myopia‐associated glaucoma (HMG) is challenging due to frequent structure–function discordance and coexisting myopia‐related changes. These changes may reduce the reliability of conventional structure–function mapping and increase the risk of misclassifying non‐glaucomatous VF abnormalities as ...
Ruby S. Chan, Ya Xing Wang, Jin Wook Jeoung, Jost B. Jonas, Minxin Liu, Ching‐Yu Cheng, Rachel S. Chong   +6 more
wiley   +1 more source