Results 241 to 250 of about 170,520 (332)

Immunoglobulin G Fc engineering for localized therapy: Eliminating neonatal Fc receptor interactions and ensuring purification using protein A

Protein Science, Volume 34, Issue 11, November 2025.
Abstract Monoclonal antibodies (mAbs) and bispecific antibodies (bsAbs) have transformed therapeutic strategies for various diseases. However, administering them can lead to unwanted adverse effects and insufficient delivery to local disease sites.
Akifumi Kato, Asami Toshima, Gennosuke Takekawa, Hikaru Miyagi, Ai Kubota, Sayaka Hori, Yasunori Uemura, Rinpei Niwa   +7 more
wiley   +1 more source

Switching to faricimab from aflibercept during maintenance treatment period for age-related macular degeneration. [PDF]

Sci Rep
Masaoka M, Yamashiro K.
europepmc   +1 more source

Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?

Acta Ophthalmologica, Volume 103, Issue 7, Page e436-e455, November 2025.
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs, Berith M. Balfoort, Marion M. Brands, Anneloor L. M. A. ten Asbroek, Camiel J. F. Boon, Roselie M. H. Diederen, Corrie Timmer, Margreet A. E. M. Wagenmakers, Hans R. Waterham, Ronald J. A. Wanders, Riekelt H. Houtkooper, Clara D. van Karnebeek, Arthur A. Bergen   +12 more
wiley   +1 more source

Efficacy and Safety of Switching from Ranibizumab to Brolucizumab in Age-Related Macular Degeneration: Multicenter Real-World Outcomes. [PDF]

Clin Ophthalmol
Hejsek L, Hrevuš M, Burova M, Beran D, Cyžová Z, Penčák M, Pařilová T, Liláková D, Veith M.   +8 more
europepmc   +1 more source

Preservatives in artificial tears: Assessing impact on dry eye symptoms

Acta Ophthalmologica, Volume 103, Issue 7, Page 823-830, November 2025.
Abstract Purpose To examine the association between the presence of dry eye disease (DED) symptoms when using BAK‐preserved artificial tears (AT) compared to preservative‐free AT. Methods In this cross‐sectional study, we used data collected as part of Project ‘Finding Ophthalmic Risk and Evaluating the Value of Eye exams and their predictive ...
Astrid Dissing Sjö, Jens Rovelt, Simone Ahrenberg, Miriam Kolko   +3 more
wiley   +1 more source

Early-onset macular drusen, a monogenic form of age-related macular degeneration. [PDF]

Am J Ophthalmol Case Rep
George LM, Ranjana M, Quinodoz M, Tang RWC, Lim WK, Gilhar NG, Farooqui SZ, Rivolta C, Fenner BJ.   +8 more
europepmc   +1 more source

Molecular genetics of age-related macular degeneration

, 2001
Edwin M. Stone
openalex   +1 more source

Comparative efficacy of intravitreal anti‐VEGF therapy for neovascular age‐related macular degeneration: A systematic review with network meta‐analysis

Acta Ophthalmologica, Volume 103, Issue 7, Page 741-763, November 2025.
Abstract The aim of this review was to evaluate the comparative efficacy of intravitreal anti‐vascular endothelial growth factor (anti‐VEGF) therapy for neovascular AMD. We searched 12 literature databases for randomised clinical trials (RCT) on anti‐VEGF therapy for neovascular AMD and extracted data on: change from baseline to 12 months in best ...
Emilie T. S. Butler, Andreas Arnold‐Vangsted, Marianne G. Schou, Rodrigo Anguita, Jakob Bjerager, Enrico Borrelli, Lasse J. Cehofski, Lorenzo Ferro Desideri, Elon H. C. van Dijk, Carsten Faber, Jakob Grauslund, Javad N. Hajari, Josef Huemer, Oliver N. Klefter, Marie Krogh Nielsen, M. Cem Sabaner, Miklos Schneider, Yousif Subhi   +17 more
wiley   +1 more source

Association between atrial fibrillation and age-related macular degeneration: A nationwide cohort study. [PDF]

Eye (Lond)
Tsai HR, Chang WC, Lee YC.
europepmc   +1 more source