Results 131 to 140 of about 53,648 (262)

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, Volume 16, Issue 6, Page 1150-1165, June 2026.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Optimized Deep Learning Framework for Diabetic Retinopathy Based on Systematic Multi‐Stage Transfer Learning and Predictive Risk Stratification

open access: yesApplied AI Letters, Volume 7, Issue 2, June 2026.
A multi‐stage transfer learning framework systematically optimizes CNN architectures for diabetic retinopathy detection and risk stratification from fundus images. EfficientNetB7 achieves 96% accuracy while a survival‐inspired model generates continuous risk scores aligned with DR severity for clinically meaningful patient risk assessment.
Mujidat Jibrin, Abdsamad Benkrid
wiley   +1 more source

The clinical utility of aflibercept for diabetic macular edema

open access: yes, 2015
Michael W StewartDepartment of Ophthalmology, Mayo School of Medicine, Jacksonville, FL, USAAbstract: The treatment of center-involving diabetic macular edema (DME) has improved because of the proven efficacy of drugs that inhibit the effects of vascular
Stewart MW
core  

Twelve‐Year Clinical Course of a Band‐Shaped Remnant in the Anterior Chamber Following Trabeculotomy With the Trabectome

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
Slit‐lamp and gonioscopic findings 4 months after Trabectome surgery. A band‐shaped remnant was observed in the inferonasal quadrant of the left eye, with continuity to the trabecular meshwork on gonioscopy. ABSTRACT Band‐shaped remnants in the anterior chamber after trabeculotomy with the Trabectome may not be associated with long‐term clinical ...
Kazunori Takeuchi   +2 more
wiley   +1 more source

Visual functioning and quality of life after pars plana vitrectomy for diabetic eye disease at Groote Schuur Hospital, Cape Town, South Africa

open access: yes, 2009
Includes abstract.Includes bibliographical references (leaves 38-43).The purpose of this study was to determine the visual function and quality of life of patients 6 months after undergoing pars plana vitrectomy for diabetic retinopathy complications at ...
Azwihangwisi, Bvumbi
core  

Optic Neuritis in the Puerperium Mimicking Severe Preeclampsia: A Neurological Differential Diagnosis in the Obstetric Emergency Setting

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Optic neuritis is an acute inflammatory disease that can cause acute visual loss. We present a case of a 22‐year‐old female in postpartum with acute headache, retroocular pain, and bilateral amaurosis. Orbit MRI revealed inflammatory changes in both neurovascular optical bundles.
Jose Luis Rojas‐Oviedo   +5 more
wiley   +1 more source

Crosstalk between endoplasmic reticulum stress and mitochondrial homeostasis: A new perspective on ophthalmic disease treatment

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
The graphical abstract follows a top‐to‐bottom flow: stressors → ER–mitochondria crosstalk → ophthalmic diseases. The central panel highlights three core mitochondria‐associated membrane function axes, color‐coded as follows: light yellow for Ca2+ homeostasis, light blue for mitochondrial dynamics, and light red for mitophagy.
Luyang Jiang   +5 more
wiley   +1 more source

Artificial Intelligence in Ophthalmology: Current Status, Challenges, and Future Perspectives

open access: yesHealth Care Science, Volume 5, Issue 3, Page 249-259, June 2026.
Current research of artificial intelligence (AI) in ophthalmology. ABSTRACT Artificial intelligence (AI) is revolutionizing ophthalmology by providing innovative solutions for disease screening, diagnosis, personalized treatment, and the delivery of global healthcare services.
She Chongyang, Tao Yong
wiley   +1 more source

Ranibizumab in the treatment of patients with visual impairment due to diabetic macular edema

open access: yesClinical Ophthalmology, 2011
Francesco Bandello1, Umberto De Benedetto1, Karl Anders Knutsson1, Maurizio Battaglia Parodi1, Maria Lucia Cascavilla1, Pierluigi Iacono21Department of Ophthalmology, University Vita-salute, Scientific Institute San Raffaele, Milan, Italy; 2Fondazione G ...
Bandello F   +5 more
doaj  

Aflibercept for clinically significant diabetic macular edema: 12-month results in daily clinical practice

open access: yes, 2018
Rafael Campos Polo, Consuelo Rubio Sánchez, Diego Manuel García Guisado, María José Díaz Luque Unit of Retina, Department of Ophthalmology, Hospital Virgen del Puerto, Plasencia, Cáceres, Spain Purpose: To ...
Rubio Sánchez C   +3 more
core  

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