Results 41 to 50 of about 450,506 (276)
New Benchmark Set of Transition-Metal Coordination Reactions for the Assessment of Density Functionals [PDF]
, 2014 We present the WCCR10 data set of ten ligand dissociation energies of large cationic transition metal complexes for the assessment of approximate exchange--correlation functionals.
Chen, Peter +3 more
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background Idiopathic ventricular fibrillation (IVF) is diagnosed in patients with ventricular fibrillation of which the origin is not identified after extensive evaluations. Recent studies suggest an association between mitral annulus disjunction (MAD),
Sanne A. Groeneveld +11 more
doaj +1 more source
Bedlam in mind: seeing and reading historical images of madness [PDF]
, 2012 In this article I explore mythical Bedlam of popular imaginings. London's Bethlem Hospital was for centuries a unique institution caring for the insane and its alter ego 'Bedlam' influenced popular stereotypes of insanity. For instance, while the type
Cross, S
core +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu +10 more
wiley +1 more source
On Being Transminded: Disabling Achievement, Enabling Exchange
Disability Studies Quarterly, 2014 We write collaboratively, as a recent graduate and long-time faculty member of a small women’s liberal arts college, about the mental health costs of adhering to a feminist narrative of achievement that insists upon independence and resiliency.
Anne Dalke, Clare Mullaney
doaj +1 more source
Inhibition of Drosophila Wg signaling involves competition between Mad and Armadillo/beta-catenin for dTcf binding. [PDF]
PLoS ONE, 2008 Precisely regulated signal transduction pathways are crucial for the regulation of developmental events and prevention of tumorigenesis. Both the Transforming Growth Factor beta (TGFbeta)/Bone morphogenetic protein (BMP) and Wnt/Wingless (Wg) pathways ...
Yi Arial Zeng +4 more
doaj +1 more source
Implementation of new closed orbit correction procedures in the MAD-X program [PDF]
, 2002 The possibility to correct a closed orbit is a basic functionality in the MAD program. During the rewrite leading to the MAD-X version, the closed orbit correction procedures have been completely re-written and substantially extended.
Herr, Werner
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown +6 more
wiley +1 more source