Results 61 to 70 of about 8,672,142 (286)

Assessing Strengths and Limitations of Magnetoencephalography Source Imaging With Intracerebral EEG

open access: yesAdvanced Science, EarlyView.
Simultaneous MEG and stereotactic EEG (SEEG) recordings provide a direct validation framework for MEG source imaging in focal epilepsy. Virtual SEEG signals derived from MEG reconstructions reveal significant agreement with intracranial measures of spike localization, resting‐state oscillations, and functional connectivity, while also identifying ...
Jawata Afnan   +10 more
wiley   +1 more source

Tom40 functions as a channel for protein retrotranslocation in the mitochondria-associated degradation (MAD) pathway

open access: yesCommunications Biology
The mitochondria-associated degradation pathway (MAD) mediates removal and elimination of damaged, unfolded mitochondrial proteins by the ubiquitin-proteasome system (UPS).
Pin-Chao Liao   +6 more
doaj   +1 more source

Optimism, ambivalence, and opportunities: staff perspectives signaling a critical turn in patient-oriented research in forensic mental health care settings

open access: yesFrontiers in Psychiatry
This qualitative descriptive study examines the views of 25 clinicians, clinical leaders, and senior hospital leaders about forensic patient-oriented research (POR) practices and the inclusion of patients as research partners in forensic mental health ...
Christopher Canning   +3 more
doaj   +1 more source

Herbicide Metabolic Resistance in Poaceae Plants via the GA‐GID1/DELLA‐DOF2‐P450s Module

open access: yesAdvanced Science, EarlyView.
Plant hormone signaling modulates herbicide resistance in Echinochloa crus‐galli. The GA–DELLA–DOF2 cascade directly activates P450 detoxification genes in two Poaceae species, uncovering a core mechanism of metabolic herbicide resistance. ABSTRACT Barnyard grass (Echinochloa crus‐galli) is one of the world's most important weeds, and the evolution of ...
Junzhi Wang   +6 more
wiley   +1 more source

Sanism: A Conceptual Analysis

open access: yesStudies in Social Justice
The concept of sanism offers a promising framework for examining the structural injustices encountered by individuals with mental health diagnoses. However, it remains inconsistently applied across the existing literature. This study aims to clarify and
Sandrine Renaud   +3 more
doaj   +1 more source

Deciphering Anti‐Cancer Drug Efficacy Through Nanomechanical Vibrations in Living Gastric Cancer Organoids

open access: yesAdvanced Science, EarlyView.
This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang   +10 more
wiley   +1 more source

A Drug‐Gated, Modular STAb‐T Immunotherapy With External Control

open access: yesAdvanced Science, EarlyView.
Engineered STAb‐TON cells act as programmable living factories that continuously secrete inactive antibody modules, which assemble extracellularly into a functional T cell engager only upon small‐molecule administration. This externally controlled platform enables reversible, on‐demand regulation of antitumor immunity, establishing a new paradigm for ...
Susana Luengo‐Arias   +23 more
wiley   +1 more source

Machine Learning Interatomic Potentials for Energy Materials: Architectures, Training Strategies, and Applications

open access: yesAdvanced Energy Materials, EarlyView.
Machine learning interatomic potentials bridge quantum accuracy and computational efficiency for materials discovery. Architectures from Gaussian process regression to equivariant graph neural networks, training strategies including active learning and foundation models, and applications in solid‐state electrolytes, batteries, electrocatalysts ...
In Kee Park   +19 more
wiley   +1 more source

Centromeric cohesion failure invokes a conserved choreography of chromosomal mis-segregations in pancreatic neuroendocrine tumor

open access: yesGenome Medicine, 2020
Background Pancreatic neuroendocrine tumors (PANETs) are rare, slow growing cancers that often present with local and distant metastasis upon detection.
Rene Quevedo   +17 more
doaj   +1 more source

Electrocatalytic Urea Waste Valorization via Water Electrolysis: Transition‐Metal Phosphides for Sustainable Hydrogen Production

open access: yesAdvanced Energy Materials, EarlyView.
This article provides a comprehensive analysis of transition metal phosphides (TMP) as electrocatalysts for urea‐assisted water electrolysis, highlighting the critical role of phosphorus engineering in modulating electronic structure, optimizing active sites, and enhancing catalytic durability.
Shivalingayya Gaddimath   +8 more
wiley   +1 more source

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