Results 131 to 140 of about 79,397 (170)

Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle

Science, 2018
How to make bioactive alkaloids Vinblastine and vincristine are important, expensive anticancer agents that are produced by dimerization of the plant-derived alkaloids catharanthine and vindoline. The enzymes that transform tabersonine into vindoline are known; however, the mechanism by which the scaffolds of catharanthine and ...
Richard Payne, Belinda Ameyaw, Scott Farrow   +2 more
exaly   +5 more sources

Green grabbing at the ‘pharm’ gate: rosy periwinkle production in southern Madagascar

Journal of Peasant Studies, 2012
The following article contrasts contemporary rosy periwinkle (Catharanthus roseus) extraction in southern Madagascar with original bioprospecting research conducted 50 years ago. My study shows how plant extraction firms have shifted their approaches by creating new labor forms, which devolve risk and increase exploitation in attempts to capture the ...
Benjamin Neimark
exaly   +2 more sources

A Systematic Review of the Pharmacological and Phytochemical Profiles of Madagascar periwinkle as Potential Dietary Supplement

Chinese Journal of Applied Physiology, 2023
Madagascar periwinkle (Catharanthus roseus) is a plant species known for its rich pharmacological and phytochemical properties. This systematic review aims to comprehensively evaluate the potential of Madagascar periwinkle as a dietary supplement. A thorough search of relevant databases yielded studies focusing on the pharmacological activities and ...
Roshan Kumar, Dubey, Satyam, Shukla, Zeashan, Hussain, Mohammad, Tasin   +3 more
openaire   +2 more sources

Transformation in Catharanthus Species (Madagascar Periwinkle)

1993
Secondary metabolite production by plant cell cultures has been the subject of many investigations. Indole alkaloids such as ajmalicine, an antihypertensive drug, or vinblastine and vincristin, two antitumor compounds produced by Catharanthus roseus, are very important in the pharmaceutical industry.
David, C., Tempe, J.
openaire   +2 more sources

Colonization of Madagascar periwinkle (Catharanthus roseus), by endophytes encoding gfp marker

Archives of Microbiology, 2013
This study reports the introduction of gfp marker in two endophytic bacterial strains (Pantoea agglomerans C33.1, isolated from cocoa, and Enterobacter cloacae PR2/7, isolated from citrus) to monitor the colonization in Madagascar perinwinkle (Catharanthus roseus).
Adalgisa Ribeiro, Torres, Welington Luiz, Araújo, Luciana, Cursino, Priscilla, de Barros Rossetto, Mateus, Mondin, Mariangela, Hungria, João Lúcio, Azevedo   +6 more
openaire   +2 more sources

Gene expression profiling of phytoplasma-infected Madagascar periwinkle leaves using differential display

Molecular Biology Reports, 2010
Phytoplasmas are small (0.2-0.8 μm), wall-less, pleiomorphic prokaryotes responsible of numerous economically important plant diseases. They are characterized by a very small genome and are obligate parasites of phloem tissues and some insects that act as vectors of infection.
De Luca V, Capasso C, Capasso A, Pastore M, Carginale V   +4 more
openaire   +4 more sources

Molecular cloning and characterisation of two calmodulin isoforms of the Madagascar periwinkle Catharanthus roseus

Plant Biology, 2010
AbstractInvolvement of Ca2+signalling in regulation of the biosynthesis of monoterpene indole alkaloids (MIA) in Catharanthus roseus has been extensively studied in recent years, albeit no protein of this signalling pathway has been isolated. Using a PCR strategy, two C.
P, Poutrain, G, Guirimand, S, Mahroug, V, Burlat, C, Melin, O, Ginis, A, Oudin, N, Giglioli-Guivarc'h, O, Pichon, V, Courdavault   +9 more
openaire   +2 more sources

Anthracnose of Madagascar periwinkle caused by species belonging to the Colletotrichum gloeosporioides species complex

Journal of General Plant Pathology, 2013
Severe blight of stems was found on Madagascar periwinkle (Catharanthus roseus) in Shizuoka and Okinawa prefectures, Japan, in July 2003 and September 2004, respectively. Similar fungi were isolated from the diseased plants. The isolated fungi caused the disease after inoculation and subsequently were reisolated from diseased tissues.
Keisuke Tomioka, Junji Nishikawa, Jouji Moriwaki, Toyozo Sato   +3 more
openaire   +1 more source

Multiple forms of NADPH-cytochrome P450 oxidoreductases in the madagascar periwinkle Catharanthus roseus

In Vitro Cellular & Developmental Biology - Plant, 2001
NADPH-cytochrome P450 oxidoreductase (CPR, EC 1.6.2.4) is the redox partner of classical P450-monooxygenases, which have crucial roles in the metabolism of terpenes, alkaloids, flavonoids, phytoalexins, etc. It becomes evident that, contrary to animals and yeast, various CPR isoforms occur in some plants, although their specific physiological functions
Blondy B. Canto-Canché, Víctor M. Loyola-Vargas   +1 more
openaire   +1 more source

Growth and alkaloids production in Madagascar periwinkle plants grown under red LED

IFAC Proceedings Volumes, 2013
Abstract Madagascar periwinkle plants containing physiologically active indole alkaloids were grown hydroponically under red light (R) from red Light-Emitting Diodes (LEDs; 660nm peak wavelength) or white light (FL) from fluorescent lamps in the enclosed artificial lighting plant factory. The effects of light quality on growth and vindoline (VIN) and
Keiko K. Ohashi, Taro Fukuyama, Akira Nakai, Hitohide Usami, Eiichi Ono, Hiroyuki Watanabe   +5 more
openaire   +1 more source