Results 1 to 10 of about 25,087 (152)
Effect of Vinblastine Timing on Skin Graft Healing in a Rat Model [PDF]
MedicinaBackground and Objectives: Chemotherapeutic agents are known to disrupt wound healing; however, the influence of administration timing on skin graft repair remains insufficiently characterized.
Eren Tuncer +5 more
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Genome-wide association studies reveal genetic variants associated with antineoplastic monoterpenoid indole alkaloid accumulation in Catharanthus roseus [PDF]
Frontiers in Plant ScienceCatharanthus roseus produces pharmacologically important monoterpenoid indole alkaloids (MIAs), yet their natural accumulation is low, limiting therapeutic exploitation. To dissect the genetic basis of natural variation in MIA accumulation, we integrated
Vyoma Mistry +9 more
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Modifications on the Basic Skeletons of Vinblastine and Vincristine
Molecules, 2012 The synthetic investigation of biologically active natural compounds serves two main purposes: (<em>i</em>) the total synthesis of alkaloids and their analogues; (<em>ii</em>) modification of the structures for producing more ...
Csaba Szántay +3 more
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Investigation of Protective Effects of Quercetin on Oxidative Stress Induced by Vinblastine in Bone Marrow of Rats [PDF]
Pharmaceutical Sciences, 2021 Background: Chemotherapy drugs such as vinblastine cause oxidative stress in the bone marrow resulting changes in blood cell production and anemia. In this study, the antioxidant and therapeutic potential of quercetin was evaluated.
Hamed Aramjoo +2 more
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Molecular Therapy: Methods & Clinical Development, 2021 Human induced pluripotent stem cell-derived intestinal epithelial cells (hiPSC-IECs) are expected to be utilized in regenerative medicine. To perform a safe transplantation without the risk of tumor formation, residual undifferentiated hiPSCs must be ...
Moe Ichikawa +5 more
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Plants, 2023 Fungal elicitation could improve the secondary metabolite contents of in vitro cultures. Herein, we report the effect of Fusarium oxysporum on vinblastine and vincristine alkaloid yields in Catharanthus roseus embryos. The study revealed increased yields
Dipti Tonk +5 more
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Investigating the Genotoxic Effect of Gamma Irradiation on L929 Cells after Vinblastine Treatment Using Micronucleus Assay on Cytokinesis-blocked Binucleated Cells [PDF]
Journal of Cell and Molecular Research, 2019 There are several studies suggesting the role of aneuploidy in tumor formation. Aneuploid cells are different from normal ones in term of gene expression and proteome.
Zahra Jomehzadeh +3 more
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Molecules, 2023 Cancer therapies use different compounds of synthetic and natural origin. However, despite some positive results, relapses are common, as standard chemotherapy regimens are not fully capable of completely eradicating cancer stem cells.
Valentina Laghezza Masci +7 more
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Frontiers in Endocrinology, 2022 BackgroundProstate cancer (PCa) is a common malignancy occurring in men. As both an endocrine and gonadal organ, prostate is closely correlated with androgen. So, androgen deprivation therapy (ADT) is effective for treating PCa.
Xi Chen +6 more
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A comparison of paclitaxel and vinblastine induced giant cell formation in murine NK/Ly lymphoma
Біологічні студії, 2011 We compared giant cell formation in murine NK/Ly lymphoma under treatment with anticancer drugs – vinblastine or paclitaxel. It was found that vinblastine caused an appearance of bigger cells than paclitaxel did, whereas paclitaxel induced more rapid ...
R. O. Horbay +2 more
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