Effect of Vinblastine Timing on Skin Graft Healing in a Rat Model [PDF]
MedicinaBackground and Objectives: Chemotherapeutic agents are known to disrupt wound healing; however, the influence of administration timing on skin graft repair remains insufficiently characterized.
Eren Tuncer +5 more
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Modifications on the Basic Skeletons of Vinblastine and Vincristine
Molecules, 2012 The synthetic investigation of biologically active natural compounds serves two main purposes: (<em>i</em>) the total synthesis of alkaloids and their analogues; (<em>ii</em>) modification of the structures for producing more ...
Peter Keglevich +2 more
exaly +3 more sources
Cytotoxicity of Esculetin Compared with Vinblastine and Paclitaxel in PC-3 Prostate Cancer Cells [PDF]
Current OncologyBackground/Objectives: Metastatic prostate cancer is among the therapy-resistant human neoplasms. PC-3 is a commonly used experimental cell line that does not express androgen receptors.
Ana I. García-Pérez +4 more
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Influence of light type, cadmium, and glycine concentration on vinblastine and vincristine production in Catharanthus roseus cell suspension culture with response surface methodology-based optimization of elicitor condition [PDF]
BMC Plant BiologyThe Catharanthus roseus contains anticancer alkaloids such as vinblastine and vincristine and has potent medicinal properties. In this study, the effects of different concentrations of plant growth regulators on callus induction, various types of LED ...
Seyed Karim Tahami +3 more
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Investigation of Protective Effects of Quercetin on Oxidative Stress Induced by Vinblastine in Bone Marrow of Rats [PDF]
Pharmaceutical Sciences, 2021 Background: Chemotherapy drugs such as vinblastine cause oxidative stress in the bone marrow resulting changes in blood cell production and anemia. In this study, the antioxidant and therapeutic potential of quercetin was evaluated.
Hamed Aramjoo +2 more
doaj +1 more source
Molecular Therapy: Methods & Clinical Development, 2021 Human induced pluripotent stem cell-derived intestinal epithelial cells (hiPSC-IECs) are expected to be utilized in regenerative medicine. To perform a safe transplantation without the risk of tumor formation, residual undifferentiated hiPSCs must be ...
Moe Ichikawa +5 more
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Molecules, 2023 Cancer therapies use different compounds of synthetic and natural origin. However, despite some positive results, relapses are common, as standard chemotherapy regimens are not fully capable of completely eradicating cancer stem cells.
Valentina Laghezza Masci +7 more
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Plants, 2023 Fungal elicitation could improve the secondary metabolite contents of in vitro cultures. Herein, we report the effect of Fusarium oxysporum on vinblastine and vincristine alkaloid yields in Catharanthus roseus embryos. The study revealed increased yields
Dipti Tonk +5 more
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Investigating the Genotoxic Effect of Gamma Irradiation on L929 Cells after Vinblastine Treatment Using Micronucleus Assay on Cytokinesis-blocked Binucleated Cells [PDF]
Journal of Cell and Molecular Research, 2019 There are several studies suggesting the role of aneuploidy in tumor formation. Aneuploid cells are different from normal ones in term of gene expression and proteome.
Zahra Jomehzadeh +3 more
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Frontiers in Endocrinology, 2022 BackgroundProstate cancer (PCa) is a common malignancy occurring in men. As both an endocrine and gonadal organ, prostate is closely correlated with androgen. So, androgen deprivation therapy (ADT) is effective for treating PCa.
Xi Chen +6 more
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