Cytotoxicity of Esculetin Compared with Vinblastine and Paclitaxel in PC-3 Prostate Cancer Cells [PDF]
Current OncologyBackground/Objectives: Metastatic prostate cancer is among the therapy-resistant human neoplasms. PC-3 is a commonly used experimental cell line that does not express androgen receptors.
Ana I. García-Pérez +4 more
doaj +2 more sources
Influence of light type, cadmium, and glycine concentration on vinblastine and vincristine production in Catharanthus roseus cell suspension culture with response surface methodology-based optimization of elicitor condition [PDF]
BMC Plant BiologyThe Catharanthus roseus contains anticancer alkaloids such as vinblastine and vincristine and has potent medicinal properties. In this study, the effects of different concentrations of plant growth regulators on callus induction, various types of LED ...
Seyed Karim Tahami +3 more
doaj +2 more sources
Investigation of Protective Effects of Quercetin on Oxidative Stress Induced by Vinblastine in Bone Marrow of Rats [PDF]
Pharmaceutical Sciences, 2021 Background: Chemotherapy drugs such as vinblastine cause oxidative stress in the bone marrow resulting changes in blood cell production and anemia. In this study, the antioxidant and therapeutic potential of quercetin was evaluated.
Hamed Aramjoo +2 more
doaj +1 more source
Molecular Therapy: Methods & Clinical Development, 2021 Human induced pluripotent stem cell-derived intestinal epithelial cells (hiPSC-IECs) are expected to be utilized in regenerative medicine. To perform a safe transplantation without the risk of tumor formation, residual undifferentiated hiPSCs must be ...
Moe Ichikawa +5 more
doaj +1 more source
Molecules, 2023 Cancer therapies use different compounds of synthetic and natural origin. However, despite some positive results, relapses are common, as standard chemotherapy regimens are not fully capable of completely eradicating cancer stem cells.
Valentina Laghezza Masci +7 more
doaj +1 more source
Plants, 2023 Fungal elicitation could improve the secondary metabolite contents of in vitro cultures. Herein, we report the effect of Fusarium oxysporum on vinblastine and vincristine alkaloid yields in Catharanthus roseus embryos. The study revealed increased yields
Dipti Tonk +5 more
doaj +1 more source
Investigating the Genotoxic Effect of Gamma Irradiation on L929 Cells after Vinblastine Treatment Using Micronucleus Assay on Cytokinesis-blocked Binucleated Cells [PDF]
Journal of Cell and Molecular Research, 2019 There are several studies suggesting the role of aneuploidy in tumor formation. Aneuploid cells are different from normal ones in term of gene expression and proteome.
Zahra Jomehzadeh +3 more
doaj +1 more source
Frontiers in Endocrinology, 2022 BackgroundProstate cancer (PCa) is a common malignancy occurring in men. As both an endocrine and gonadal organ, prostate is closely correlated with androgen. So, androgen deprivation therapy (ADT) is effective for treating PCa.
Xi Chen +6 more
doaj +1 more source
A comparison of paclitaxel and vinblastine induced giant cell formation in murine NK/Ly lymphoma
Біологічні студії, 2011 We compared giant cell formation in murine NK/Ly lymphoma under treatment with anticancer drugs – vinblastine or paclitaxel. It was found that vinblastine caused an appearance of bigger cells than paclitaxel did, whereas paclitaxel induced more rapid ...
R. O. Horbay +2 more
doaj +1 more source
Tyrosine kinase inhibitors as an alternative treatment in canine mast cell tumor
Frontiers in Veterinary Science, 2023 The current gold standard treatment for canine mast cell tumors (MCT) uses vinblastine sulfate (VBL) as chemotherapy, although tyrosine kinase inhibitors (TKI) have recently been shown to be worthy candidates for treatment.
Yasmin Nascimento Bernardes Coelho +6 more
doaj +1 more source