Results 11 to 20 of about 24,081 (149)

A comparison of paclitaxel and vinblastine induced giant cell formation in murine NK/Ly lymphoma

open access: yesБіологічні студії, 2011
We compared giant cell formation in murine NK/Ly lymphoma under treatment with anticancer drugs – vinblastine or paclitaxel. It was found that vinblastine caused an appearance of bigger cells than paclitaxel did, whereas paclitaxel induced more rapid ...
R. O. Horbay   +2 more
doaj   +1 more source

Tyrosine kinase inhibitors as an alternative treatment in canine mast cell tumor

open access: yesFrontiers in Veterinary Science, 2023
The current gold standard treatment for canine mast cell tumors (MCT) uses vinblastine sulfate (VBL) as chemotherapy, although tyrosine kinase inhibitors (TKI) have recently been shown to be worthy candidates for treatment.
Yasmin Nascimento Bernardes Coelho   +6 more
doaj   +1 more source

Study of Desorbtion and Exemption of Terpeno-indole Alkaloids of Vinkristin and Vinblastin from Erythrocitary Cell Carriers

open access: yesРазработка и регистрация лекарственных средств, 2019
Introduction. Employees of the Department of Pharmaceutical Chemistry and Pharmaceutical Technology have obtained modified forms of terpino-indole alkaloids (ТIA) and vinbristine (VCR) and vinblastine (VBL) known in the treatment of cancer diseases by ...
O. V. Trineeva, A. D. Khalahakun
doaj   +1 more source

Genome-wide identification of NAC transcription factors and regulation of monoterpenoid indole alkaloid biosynthesis in Catharanthus roseus

open access: yesFrontiers in Plant Science, 2023
NAC transcription factors (TFs) are crucial to growth and defense responses in plants. Though NACs have been characterized for their role in several plants, comprehensive information regarding their role in Catharanthus roseus, a perennial ornamental ...
Jawad Ahmed   +9 more
doaj   +1 more source

A Nonselective Cyclooxygenase Inhibitor Enhances the Activity of Vinblastine in a Naturally-Occurring Canine Model of Invasive Urothelial Carcinoma

open access: yesBladder Cancer, 2016
Background: Chemotherapy is expected to remain an important part of invasive urothelial carcinoma (UC) treatment. Strategies to enhance chemotherapy efficacy are needed.
Deborah W. Knapp   +5 more
doaj   +1 more source

Catharanthus roseus (L.) G. Don - plant regeneration and alkaloids content

open access: yesActa Societatis Botanicorum Poloniae, 2014
We describe here a regeneration of plantlets of Catharanthus roseus (L.) G. Don from shoot tips and axillary buds. Shoot tips were excised from 7-day-old seedlings and were incubated in solid Nitsch and Nitsch (NN) medium supplemented with kinetin ...
Mirosława Furmanowa   +3 more
doaj   +1 more source

Imatinib Mesylate for the Treatment of Canine Mast Cell Tumors: Assessment of the Response and Adverse Events in Comparison with the Conventional Therapy with Vinblastine and Prednisone

open access: yesCells, 2022
Mast cell tumors (MCTs) are common neoplasms in dogs, and treatments for these diseases include surgery, polychemotherapy and targeted therapy with tyrosine kinase inhibitors.
Thais Rodrigues Macedo   +9 more
doaj   +1 more source

Development of a Cell Suspension Culture System for Promoting Alkaloid and Vinca Alkaloid Biosynthesis Using Endophytic Fungi Isolated from Local Catharanthus roseus

open access: yesPlants, 2021
Cell and tissue cultures of Catharanthus roseus have been studied extensively as an alternative strategy to improve the production of valuable secondary metabolites. The purpose of this study was to produce C. roseus callus and suspension cell biomass of
Tran My Linh   +6 more
doaj   +1 more source

Discovery of active site of vinblastine as application of nanotechnology in medicine [PDF]

open access: yesNanomedicine Journal, 2014
Objective(s): Vinblastine is antimitotic, anticancer medicine that disturbs normal microtubule formation and favours depolymerisation. Structural study and finding the active site of vinblastine are the targets of this research.
Zahra varmaghani   +2 more
doaj  

Clinical and immunohistochemical findings of splenic mast cell tumour in a cat: A case report

open access: yesVeterinární Medicína, 2021
A 6-year-old, spayed, female, domestic shorthair cat presented with a 4-month history of chronic intermittent vomiting and anorexia. The haematologic results indicated moderate anaemia and a circulating mast cell population.
S Lee   +10 more
doaj   +1 more source

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