Results 1 to 10 of about 4,886 (206)

Chemical constituents from Tabernaemontana catharinensis root bark: a brief NMR review of indole alkaloids and in vitro cytotoxicity [PDF]

Química Nova, 2008
This work describes the isolation and structural determination of pharmacological compounds present in the bark of roots of Tabernaemontana catharinensis (Apocynaceae).
Paulo Sérgio Pereira, Suzelei de Castro França, Paulo Vinicius Anderson de Oliveira, Camila Moniz de Souza Breves, Sarazete Izidia Vaz Pereira, Suely Vilela Sampaio, Auro Nomizo, Diones Aparecida Dias   +7 more
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Effect of Aspergillus flavus Fungal Elicitor on the Production of Terpenoid Indole Alkaloids in Catharanthus roseus Cambial Meristematic Cells [PDF]

Molecules, 2018
This study reported the inducing effect of Aspergillus flavus fungal elicitor on biosynthesis of terpenoid indole alkaloids (TIAs) in Catharanthus roseus cambial meristematic cells (CMCs) and its inducing mechanism. According to the results determined by
Chuxin Liang, Chang Chen, Pengfei Zhou, Lv Xu, Jianhua Zhu, Jincai Liang, Jiachen Zi, Rongmin Yu   +7 more
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Enhanced accumulation of anticancer compounds in C. roseus hairy root cultures through elicitation and precursor feeding [PDF]

Scientific Reports
Catharanthus roseus is a medicinal plant known for producing numerous indole terpenoid alkaloids. This study investigated the effects of methyl jasmonate, yeast extract, tryptophan, and tryptamine on the accumulation of four key alkaloids—ajmalicine ...
Mohamed R. Rady, Dalia M. Mabrouk, Mona M. Ibrahim   +2 more
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Evaluation of the expression pattern of TIAs pathway genes in response to tryptophan amino acid treatment and drought stress in Catharanthus roseus. [PDF]

PLoS ONE
The leaves of the medicinal-ornamental plant Catharanthus roseus serve as the exclusive source of the anticancer alkaloids vinblastine and vincristine.
Farshid Yousefi, Alireza Abdali Mashhadi, Amin Lotfi Jalal Abadi, Alireza Shafeinia, Saied Jalily, Narges Soltani   +5 more
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Phenotypic Variability and Anticancer Alkaloid Profiles of Catharanthus roseus Cultivars Grown Under a Vertical Farming System [PDF]

Plants
Plants are promising biofactories for high-value compounds, and integrating vertical farming (VF) with plant molecular farming (PMF) enhances the efficiency and sustainability of these systems.
Marisa S. C. Lourenço, Victor Freitas, Ep Heuvelink, Susana M. P. Carvalho   +3 more
doaj   +2 more sources

Explant origin and growth regulators as determinants of callus performance and terpenoid indole alkaloid accumulation in Catharanthus roseus [PDF]

BMC Plant Biology
Catharanthus roseus (L.) G. Don (Apocynaceae) is a highly important medicinal plant and a valuable source of diverse pharmacologically active compounds particularly anticancer terpenoid indole alkaloids (TIAs), such as catharanthine (CAT), vinblastine ...
Abeer F. Desouky, Salah El-Din El-Assal, Ahmed Abdelsamad, Abdel-Salam Reda, Nancy Danial, Moemen S. Hanafy   +5 more
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Comprehensive analysis of SPL gene family and miR156a/SPLs in the regulation of terpenoid indole alkaloid biosynthesis in Catharanthus roseus L [PDF]

BMC Plant Biology
Background Catharanthus roseus (C. roseus), belongs to the dogbane family Apocynaceae, is the source of various terpenoid indole alkaloids (TIAs) with excellent antitumor properties, including vinblastine, vincristine, ajmalicine, serpentine, vindoline ...
Yaojie Zhang, Xiaofan Ni, Xueqing Fu, Ayat Taheri, Wei Zhang, Pin Liu, Hang Liu, Ling Li, Yuliang Wang, Kexuan Tang   +9 more
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Synergistic effects of H2O2, melatonin, and L-cysteine on biochemical traits and alkaloid accumulation in Catharanthus roseus L. “Ocellatus” in vitro plants [PDF]

BMC Plant Biology
Background Elicitation is a widely used strategy to enhance secondary metabolite production in medicinal plants. However, the comparative effectiveness of different redox-modulating elicitors and their interactions in regulating antioxidant systems and ...
Elham Jafarpour, Mohsen Sanikhani, Azizollah Kheiry, Farhang Razavi   +3 more
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Identification and Functional Characterization of a Geraniol Synthase UrGES from Uncaria rhynchophylla [PDF]

Plants
Uncaria rhynchophylla, a medicinal plant extensively used in traditional Chinese medicine, is an important plant source of terpenoid indole alkaloids (TIAs), but the mechanism of TIA biosynthesis at molecular level remains unclear. Geraniol synthase (GES)
Xinghui Liu, Wenqiang Chen, Linxuan Li, Detian Mu, Iain W. Wilson, Xueshuang Huang, Yahui Xiang, Lina Zhu, Limei Pan, Deyou Qiu, Qi Tang   +10 more
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Exploration of the Mechanisms of Differential Indole Alkaloid Biosynthesis in Dedifferentiated and Cambial Meristematic Cells of Catharanthus roseus Using Transcriptome Sequencing

Frontiers in Genetics, 2022
Catharanthus roseus produces terpenoid indole alkaloids (TIAs) of high medicinal importance. The current research focuses on finding an efficient production system such as cell suspension cultures for high TIA concentrations.
Pengfei Zhou, Mingxiang Chen
doaj   +1 more source