Effect of Aspergillus flavus Fungal Elicitor on the Production of Terpenoid Indole Alkaloids in Catharanthus roseus Cambial Meristematic Cells [PDF]
Molecules, 2018 This study reported the inducing effect of Aspergillus flavus fungal elicitor on biosynthesis of terpenoid indole alkaloids (TIAs) in Catharanthus roseus cambial meristematic cells (CMCs) and its inducing mechanism. According to the results determined by
Chuxin Liang +7 more
doaj +2 more sources
Enhanced accumulation of anticancer compounds in C. roseus hairy root cultures through elicitation and precursor feeding [PDF]
Scientific ReportsCatharanthus roseus is a medicinal plant known for producing numerous indole terpenoid alkaloids. This study investigated the effects of methyl jasmonate, yeast extract, tryptophan, and tryptamine on the accumulation of four key alkaloids—ajmalicine ...
Mohamed R. Rady +3 more
doaj +2 more sources
Evaluation of the expression pattern of TIAs pathway genes in response to tryptophan amino acid treatment and drought stress in Catharanthus roseus. [PDF]
PLoS ONEThe leaves of the medicinal-ornamental plant Catharanthus roseus serve as the exclusive source of the anticancer alkaloids vinblastine and vincristine.
Farshid Yousefi +5 more
doaj +2 more sources
Phenotypic Variability and Anticancer Alkaloid Profiles of Catharanthus roseus Cultivars Grown Under a Vertical Farming System [PDF]
PlantsPlants are promising biofactories for high-value compounds, and integrating vertical farming (VF) with plant molecular farming (PMF) enhances the efficiency and sustainability of these systems.
Marisa S. C. Lourenço +3 more
doaj +2 more sources
Explant origin and growth regulators as determinants of callus performance and terpenoid indole alkaloid accumulation in Catharanthus roseus [PDF]
BMC Plant BiologyCatharanthus roseus (L.) G. Don (Apocynaceae) is a highly important medicinal plant and a valuable source of diverse pharmacologically active compounds particularly anticancer terpenoid indole alkaloids (TIAs), such as catharanthine (CAT), vinblastine ...
Abeer F. Desouky +5 more
doaj +2 more sources
Synergistic effects of H2O2, melatonin, and L-cysteine on biochemical traits and alkaloid accumulation in Catharanthus roseus L. “Ocellatus” in vitro plants [PDF]
BMC Plant BiologyBackground Elicitation is a widely used strategy to enhance secondary metabolite production in medicinal plants. However, the comparative effectiveness of different redox-modulating elicitors and their interactions in regulating antioxidant systems and ...
Elham Jafarpour +3 more
doaj +2 more sources
Frontiers in Genetics, 2022 Catharanthus roseus produces terpenoid indole alkaloids (TIAs) of high medicinal importance. The current research focuses on finding an efficient production system such as cell suspension cultures for high TIA concentrations.
Pengfei Zhou, Mingxiang Chen
doaj +1 more source
Journal of Pure and Applied Microbiology, 2021 The medicinal plant C. roseus synthesizes biologically active alkaloids via the terpenoid indole alkaloid (TIAs) biosynthetic pathway. Most of these alkaloids have high therapeutic value, such as vinblastine and vincristine.
Mukesh Kumar Sharma, Mohan Kumar, Renu
doaj +1 more source
Plants, 2021 Cell and tissue cultures of Catharanthus roseus have been studied extensively as an alternative strategy to improve the production of valuable secondary metabolites. The purpose of this study was to produce C. roseus callus and suspension cell biomass of
Tran My Linh +6 more
doaj +1 more source
Frontiers in Plant Science, 2022 Dendrobium officinale is both a traditional herbal medicine and a plant of high ornamental and medicinal value. Alkaloids, especially terpenoid indole alkaloids (TIAs), with pharmacological activities are present in the tissues of D. officinale. A number
Chunyan Jiao +8 more
doaj +1 more source