Ornamental Exterior versus Therapeutic Interior of Madagascar Periwinkle (Catharanthus roseus): The Two Faces of a Versatile Herb [PDF]
Catharanthus roseus (L.) known as Madagascar periwinkle (MP) is a legendary medicinal plant mostly because of possessing two invaluable antitumor terpenoid indole alkaloids (TIAs), vincristine and vinblastine.
Naghmeh Nejat +2 more
exaly +3 more sources
An updated version of the Madagascar periwinkle genome [version 1; peer review: 2 approved] [PDF]
The Madagascar periwinkle, Catharanthus roseus, belongs to the Apocynaceae family. This medicinal plant, endemic to Madagascar, produces many important drugs including the monoterpene indole alkaloids (MIA) vincristine and vinblastine used to treat ...
Sarah Ellen O'Connor +13 more
doaj +2 more sources
Cellular and Subcellular Compartmentation of the 2C-Methyl-D-Erythritol 4-Phosphate Pathway in the Madagascar Periwinkle [PDF]
The Madagascar periwinkle (Catharanthus roseus) synthesizes the highly valuable monoterpene indole alkaloids (MIAs) through a long metabolic route initiated by the 2C-methyl-D-erythritol 4-phosphate (MEP) pathway. In leaves, a complex compartmentation of
Grégory Guirimand +14 more
doaj +2 more sources
BDFlower: Growth stage flower image dataset for precision agriculture and floricultureMendeley Data [PDF]
This study presents a comprehensive BDFlower growth stage dataset designed to support research in precision agriculture and floriculture. The dataset encompasses eight common flower species found in Bangladesh: Bush Allamanda, Red Hibiscus, Yellow Bell ...
Aritra Das +4 more
doaj +2 more sources
Double flower is associated with defects in a Phantastica-like gene in Catharanthus roseus [PDF]
Floral morphological traits, such as double-flowering, are important aspects of the commercial value of ornamental plants. Commercially available double-flower Madagascar periwinkle (Catharanthus roseus), cv.
Koichi Tomomatsu +7 more
doaj +2 more sources
The Complete Plastid Genome Sequence of Madagascar Periwinkle Catharanthus roseus (L.) G. Don: Plastid Genome Evolution, Molecular Marker Identification, and Phylogenetic Implications in Asterids. [PDF]
The Madagascar periwinkle (Catharanthusroseus in the family Apocynaceae) is an important medicinal plant and is the source of several widely marketed chemotherapeutic drugs.
Chuan Ku +3 more
doaj +2 more sources
Mechanistic and kinetic modeling of cadmium and lead phytoextraction by Madagascar Periwinkle [Catharanthus roseus (L.) G.Don] in battery waste contaminated soil [PDF]
Remediation of heavy metal-contaminated soils is critical due to their persistent toxicity and threat to food security and ecosystem health. Therefore, a study was conducted during September to November 2024 to assess the phytoextraction potential of ...
Arwa A. AL-Huqail +6 more
doaj +2 more sources
Kaposiform hemangioendothelioma: Diagnosis and treatment [PDF]
Vascular endothelial growth factor‐C (VEGF‐C)/vascular endothelial growth factor receptor‐3 (VEGFR‐3) and angiopoietin‐2 (Ang‐2)/tyrosine kinase with immunoglobulin‐like and EGF‐like domain 2 (TIE2) signaling pathways play an important role in lymphangiogenesis.
Tian Y, Tian Y, Wei L, Xu Z, Li L, Ma L.
europepmc +2 more sources
Tabernaemontana catharinensis: A Source of Indole Alkaloids With Potential Activity as Chemotherapeutic Agents. [PDF]
ABSTRACT This study aimed to evaluate the antitumor activity of fractions rich in indole alkaloids extracted from the leaves of the species Tabernaemontana catharinensis. The chemical composition was analyzed using high‐resolution mass spectrometry (HRMS), which identified nine known indole alkaloids, including voacangine, voacangine hydroxyindolenine,
Donada AJG +5 more
europepmc +2 more sources
Oxidation of four monoterpenoid indole alkaloid classes by three cytochrome P450 monooxygenases from Tabernaemontana litoralis. [PDF]
SUMMARY Cytochrome P450 monooxygenases (CYPs) are well known for their ability to catalyze diverse oxidation reactions, playing a significant role in the biosynthesis of various natural products. In the realm of monoterpenoid indole alkaloids (MIAs), one of the largest groups of alkaloids in nature, CYPs are integral to reactions such as hydroxylation,
Mai Z +10 more
europepmc +2 more sources

