Antidiabetic and Antioxidant Properties of Alkaloids from Catharanthus roseus (L.) G. Don
Molecules, 2013 Catharanthus roseus (L.) G. Don is a herbal plant traditionally used by local populations in India, South Africa, China and Malaysia to treat diabetes. The present study reports the in vitro antioxidant and antidiabetic activities of the major alkaloids ...
Chung Yeng Looi +2 more
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Frontiers in Plant Science, 2019 Catharanthus roseus contains a variety of monoterpenoid indole alkaloids (MIAs), among which bisindole alkaloids vinblastine and vincristine are well-known to have antitumor effects and widely used in clinical treatment.
Qifang Pan, Hang Wang, Xueqing Fu
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Binary Stress Induces an Increase in Indole Alkaloid Biosynthesis in Catharanthus roseus [PDF]
Frontiers in Plant Science, 2015 Catharanthus roseus is an important medicinal plant, which produces a variety of indole alkaloids of significant pharmaceutical relevance. In the present study, we aimed to investigate the potential stress-induced increase of indole alkaloid biosynthesis
Wei eZhu +5 more
doaj +3 more sources
Enhanced accumulation of anticancer compounds in C. roseus hairy root cultures through elicitation and precursor feeding [PDF]
Scientific ReportsCatharanthus roseus is a medicinal plant known for producing numerous indole terpenoid alkaloids. This study investigated the effects of methyl jasmonate, yeast extract, tryptophan, and tryptamine on the accumulation of four key alkaloids—ajmalicine ...
Mohamed R. Rady +2 more
doaj +2 more sources
Journal of Radiation Research and Applied Sciences, 2015 Catharanthus roseus (L.) G. Don (Family Apocynaceae) is a medicinal plant that produces indole alkaloids used in cancer chemotherapy. The anticancerous alkaloids, viz. vinblastine and vincristine, are mainly present in the leaves of C. roseus.
M Naeem, Tariq Aftab, Mohd Idrees
exaly +3 more sources
Phenotypic Variability and Anticancer Alkaloid Profiles of Catharanthus roseus Cultivars Grown Under a Vertical Farming System [PDF]
PlantsPlants are promising biofactories for high-value compounds, and integrating vertical farming (VF) with plant molecular farming (PMF) enhances the efficiency and sustainability of these systems.
Marisa S. C. Lourenço +3 more
doaj +2 more sources
Pharmacological potential of bioactive compounds in Catharanthus roseus extract: A comprehensive review [PDF]
Toxicology ReportsThe pharmacological potential of bioactive compounds found in the plant, Catharanthus roseus, have diverse medicinal applications. Key constituents such as vinblastine and vincristine play an important role in cancer therapy due to their ability to ...
Keren Celestina Mendonce +5 more
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HPLC-ESI-HRMS/MS-Based Metabolite Profiling and Bioactivity Assessment of Catharanthus roseus [PDF]
PlantsA comprehensive metabolic profiling of Catharanthus roseus (L.) G. Don was performed using tandem mass spectrometry, along with an evaluation of the biological activities of its various solvent extracts. Among these, the methanolic leaf extract exhibited
Soniya Joshi +7 more
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Indole Alkaloids from Catharanthus roseus: Bioproduction and Their Effect on Human Health
Molecules, 2015 Catharanthus roseus is a medicinal plant belonging to the family Apocynaceae which produces terpenoid indole alkaloids (TIAs) of high medicinal importance.
Lorena Almagro +2 more
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Analysis and characteristics of coronaridine, an alkaloid found in <i>Catharanthus roseus</i>. [PDF]
Plant Biotechnol (Tokyo)Coronaridine, a monoterpenoid indole alkaloid, is present in Tabernanthe iboga and the related species Tabernaemontana divaricata. Recent exhaustive analysis revealed its presence in Catharanthus roseus, though specific details remain unknown. We conducted a detailed analysis of coronaridine in C.
Kisaka H +5 more
europepmc +3 more sources