Results 21 to 30 of about 2,691 (173)

Twin effects of fungal elicitor produced from Alternaria alternata on induced systemic resistance and secondary metabolites production in Catharanthus roseus (L.) G. Don

Plant Stress, 2022
Catharanthus roseus L. (G.) Don is an ornamental plant with a source of medicinally important secondary metabolites i.e., bis-indole alkaloids. Whereas, Catharanthus provides itself as a single source of two anti-cancerous alkaloids (vinblastine and ...
Anamika Paul, Nehan Shamim, Krishnendu Acharya, Nilanjan Chakraborty   +3 more
doaj   +1 more source

Report on Vincristine-Producing Endophytic Fungus Nigrospora zimmermanii from Leaves of Catharanthus roseus

Metabolites, 2022
Vincristine is an anti-cancer compound and one of the most crucial vinca alkaloids produced by the medicinal plant Catharanthus roseus (L.) G. Don. (Apocynaceae). This plant is home to hundreds of endophytic microbes, which produce a variety of bioactive
Kanchan Birat, Reem Binsuwaidan, Tariq Omar Siddiqi, Showkat Rasool Mir, Nawaf Alshammari, Mohd Adnan, Rahila Nazir, Bushra Ejaz, Moien Qadir Malik, Rikeshwer Prasad Dewangan, Syed Amir Ashraf, Bibhu Prasad Panda   +11 more
doaj   +1 more source

Alkaloide aus Catharanthus roseus-Zellkulturen, III [1] / Alkaloids from Catharanthus roseus Tissue Cultures, III [1]

Zeitschrift für Naturforschung B, 1981
Abstract From the methanol extract of Catharanthus roseus tissue cultures sitsirikine (2), isositsirikine (3), dihydrositsirikine (4), yohimbine (5), 3-iso-19-epiajmalicine (6), pleio-carpamine (7), antirhin (8) and two up to now unknown alkaloids have been isolated in addition to the compounds previously found in the hexane extract ...
Werner Kohl, Barbara Witte, Gerhard Höfle   +2 more
openaire   +1 more source

Monoterpenoid Indole Alkaloids from Cultivated in Yunnan

Natural Product Communications, 2015
A new monoterpenoid indole alkaloid, 15,20-dehydro-3α-(2-oxopropyl) coronaridine (1) , along with sixteen analogues (2–17) were isolated from the leaves of Catharanthus roseus cultivated in Yunnan.
Bei Wang, Lu Liu, Ying-Ying Chen, Qiong Li, Dan Li, Ya-Ping Liu, Xiao-Dong Luo   +6 more
doaj   +1 more source

Mitotic Block of Human Blood Cells by Vinca herbacea, Catharanthus roseus and Colchicine Alkaloids [PDF]

Journal of Medicinal Plants and By-products, 2018
Catharanthus roseus (L.) G.Don is a plant which produces anticancer and anti-mitotic indole alkaloids. Colchicine is an anti-mitotic drug. Anti-mitotic effects of Vinca herbacea Waldst. & Kit. indole alkaloids is unknown.
Babak Delnavaz Hashemloian, Azra Ataei Azimi   +1 more
doaj  

Cloning and Overexpression of Strictosidine β-D-Glucosidase Gene Short Sequence from Catharanthus roseus in Escherichia coli [PDF]

Advanced Pharmaceutical Bulletin, 2019
Purpose: Strictosidine-β-D-glucosidase (SGD) is considered as a key enzyme in the production of bisindole alkaloids in Catharanthus roseus. The present study illustrated the production of a short sequence of this enzyme in Escherichia coli without codon ...
Ahmed Saeed Arafa, Amany Elsayed Ragab, Abdel-Rahim Sayed Ibrahim, Wael Saad Abdel-Mageed, Mahmoud Emam Nasr   +4 more
doaj   +1 more source

Biosynthesis and regulation of terpenoid indole alkaloids in Catharanthus roseus

Pharmacognosy Reviews, 2015
Catharanthus roseus produces a wide range of terpenoid indole alkaloids (TIA). Many of them, such as vinblastine and vincristine, have significant bioactivity. They are valuable chemotherapy drugs used in combination with other drugs to treat lymphoma and leukemia.
Zhu, Jianhua, Wang, Mingxuan, Wen, Wei, Yu, Rongmin   +3 more
openaire   +3 more sources

Artemisinic Acid Serves as a Novel Inducer to Enhance Biosynthesis of Terpenoid Indole Alkaloids in Cambial Meristematic Cells

Natural Product Communications, 2016
To investigate the effect of artemisinic acid (AA) on improving the production of terpenoid indole alkaloids (TIAs) of Catharanthus roseus cambial meristematic cells (CMCs), feeding AA to C.
Mingxuan Wang, Jiachen Zi, Jianhua Zhu, Shan Chen, Pu Wang, Liyan Song, Rongmin Yu   +6 more
doaj   +1 more source

The Cadin-2-en-1β-ol-1β-d-glucuronopyranoside Suppresses TPA-Mediated Matrix Metalloproteinase-9 Expression Through the ERK Signaling Pathway in MCF-7 Human Breast Adenocarcinoma Cells

Journal of Pharmacological Sciences, 2012
A sesquiterpene glycoside, cadin-2-en-1β-ol-1β-D-glucuronopyranoside (known as CR4-1), was isolated from Catharanthus roseus (Apocynaceae) hairy root cultures. C. roseus is widely used as an ornamental and medicinal plant and is cultivated mainly for its
Jung-Hee Kim, Man Sub Kim, Yesol Bak, Ill-Min Chung, Do-Young Yoon   +4 more
doaj   +1 more source

In Silico Evaluation of Pharmacokinetics and Toxicity Profile of AlkaloidsPresent in Leaves of Catharanthus roseus L.

RGUHS Journal of Pharmaceutical Sciences
Background Catharanthus roseus Madagascar periwinkle is a well-known medicinal plant that produces a variety of alkaloids with significant pharmacological activities particularly in cancer and diabetes treatment.Aim This study aimed ...
Ramgopal M Dhanwad, Usha R, Ganesh S
doaj   +1 more source